Differences in Inflammatory Pathways Between Dutch South Asians vs Dutch Europids With Type 2 Diabetes

Abstract Context South Asian individuals are more prone to develop type 2 diabetes (T2D) coinciding with earlier complications than Europids. While inflammation plays a central role in the development and progression of T2D, this factor is still underexplored in South Asians. Objective This work aim...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2023-04, Vol.108 (4), p.931-940
Hauptverfasser:	Straat, Maaike E, Martinez-Tellez, Borja, van Eyk, Huub J, Bizino, Maurice B, van Veen, Suzanne, Vianello, Eleonora, Stienstra, Rinke, Ottenhoff, Tom H M, Lamb, Hildo J, Smit, Johannes W A, Jazet, Ingrid M, Rensen, Patrick C N, Boon, Mariëtte R
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Asian people Asians B cells Beta cells Biological response modifiers Body Mass Index CD19 antigen Clinical Clinical trials CXCR5 protein Development and progression Diabetes Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - ethnology Diabetes Mellitus, Type 2 - genetics Ethnicity Ethylenediaminetetraacetic acid European People Fc receptors Female Gene expression Genes Humans Inflammation Interferon Liraglutide Male Messenger RNA Microfluidics Middle Aged Pax5 protein Signal transduction South Asian People Type 2 diabetes γ-Interferon
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