Recycling of modified H2A-H2B provides short-term memory of chromatin states

Chromatin landscapes are disrupted during DNA replication and must be restored faithfully to maintain genome regulation and cell identity. The histone H3-H4 modification landscape is restored by parental histone recycling and modification of new histones. How DNA replication impacts on histone H2A-H...

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Veröffentlicht in:	Cell 2023-03, Vol.186 (5), p.1050-1065.e19
Hauptverfasser:	Flury, Valentin, Reverón-Gómez, Nazaret, Alcaraz, Nicolas, Stewart-Morgan, Kathleen R., Wenger, Alice, Klose, Robert J., Groth, Anja
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Cycle Chromatin DNA Replication H2A H2A.Z H2B histone PTM cross talk histone recycling Histones - metabolism Memory, Short-Term Mice Nucleosomes polycomb post-translational modifications Rabbits ubiquitination
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