Binding sites in the epidermal growth factor receptor are responsible for bisphenol S effects on trophoblast cell invasion

Bisphenol S (BPS) is an endocrine disrupting chemical and the second most abundant bisphenol detected in humans. We have recently demonstrated that in utero exposure to BPS reduces human placenta cell fusion by interfering with epidermal growth factor (EGF)-dependent EGF receptor (EGFR) activation....

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Veröffentlicht in:	Chemosphere (Oxford) 2023-03, Vol.318, p.137960-137960, Article 137960
Hauptverfasser:	Ticiani, Elvis, Villegas, José A., Murga-Zamalloa, Carlos, Veiga-Lopez, Almudena
Format:	Artikel
Sprache:	eng
Schlagworte:	Benzhydryl Compounds - metabolism Binding Sites Bisphenols Epidermal Growth Factor - pharmacology ErbB Receptors - metabolism Female Humans Membrane receptor Molecular docking Mutagenesis Pregnancy Trophoblasts
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