Pediatric Gastric Adenocarcinoma Presenting As Hip Pain
The third most lethal cancer in the world is gastric adenocarcinoma, which is uncommon in children. Patients with gastric adenocarcinoma typically experience vomiting, abdominal pain, anemia, and weight loss. We present a case of a 14.5-year-old male with gastric adenocarcinoma that manifested as le...
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| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2023-02, Vol.15 (2), p.e34651 |
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| creator | Sobh, Mohammed J Al Jayyousi, Obada A Mahasna, Ahmad Sobh, Rawan J |
| description | The third most lethal cancer in the world is gastric adenocarcinoma, which is uncommon in children. Patients with gastric adenocarcinoma typically experience vomiting, abdominal pain, anemia, and weight loss. We present a case of a 14.5-year-old male with gastric adenocarcinoma that manifested as left hip pain, epigastric pain, dysphagia, weight loss, and melena. Physical exam revealed cachexia, jaundice, a palpable epigastric mass, palpable liver edge, and left hip tenderness. Laboratory tests showed microcytic anemia, increase in carcinoembryonic antigen (CEA), and abnormal liver function test. Endoscopy revealed a cardial mass extending to the esophagus involving the gastroesophageal junction (GEJ). The gastric mass biopsy was consistent with invasive, moderately-differentiated gastric adenocarcinoma, which confirmed the diagnosis of gastric adenocarcinoma. Furthermore, a bone isotope scan revealed mildly hypervascular active bone pathology within the left proximal femur implying possible metastasis. Computed tomography scans and barium swallow were also helpful in supporting the diagnosis. Our case report emphasizes that gastric adenocarcinoma should be encompassed in the differential diagnosis of pediatric patients with hip pain. |
| doi_str_mv | 10.7759/cureus.34651 |
| format | Article |
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Patients with gastric adenocarcinoma typically experience vomiting, abdominal pain, anemia, and weight loss. We present a case of a 14.5-year-old male with gastric adenocarcinoma that manifested as left hip pain, epigastric pain, dysphagia, weight loss, and melena. Physical exam revealed cachexia, jaundice, a palpable epigastric mass, palpable liver edge, and left hip tenderness. Laboratory tests showed microcytic anemia, increase in carcinoembryonic antigen (CEA), and abnormal liver function test. Endoscopy revealed a cardial mass extending to the esophagus involving the gastroesophageal junction (GEJ). The gastric mass biopsy was consistent with invasive, moderately-differentiated gastric adenocarcinoma, which confirmed the diagnosis of gastric adenocarcinoma. Furthermore, a bone isotope scan revealed mildly hypervascular active bone pathology within the left proximal femur implying possible metastasis. Computed tomography scans and barium swallow were also helpful in supporting the diagnosis. Our case report emphasizes that gastric adenocarcinoma should be encompassed in the differential diagnosis of pediatric patients with hip pain.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.34651</identifier><identifier>PMID: 36895530</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Abdomen ; Anemia ; Antigens ; Barium ; Biomarkers ; Biopsy ; Blood ; Case reports ; Dysphagia ; Endoscopy ; Esophagus ; Families & family life ; Family medical history ; Gastric cancer ; Gastroenterology ; Gastrointestinal surgery ; Hemoglobin ; Liver ; Lymphatic system ; Medical diagnosis ; Medical prognosis ; Metastasis ; Mutation ; Oncology ; Ostomy ; Pain ; Patients ; Pediatrics ; Young adults</subject><ispartof>Curēus (Palo Alto, CA), 2023-02, Vol.15 (2), p.e34651</ispartof><rights>Copyright © 2023, Sobh et al.</rights><rights>Copyright © 2023, Sobh et al. This work is published under https://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2023, Sobh et al. 2023 Sobh et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c266t-e04906770e918523f643ef589f64dd9f7c4b394b37c7a7c1c2df261e96cc963f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991019/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9991019/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36895530$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sobh, Mohammed J</creatorcontrib><creatorcontrib>Al Jayyousi, Obada A</creatorcontrib><creatorcontrib>Mahasna, Ahmad</creatorcontrib><creatorcontrib>Sobh, Rawan J</creatorcontrib><title>Pediatric Gastric Adenocarcinoma Presenting As Hip Pain</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>The third most lethal cancer in the world is gastric adenocarcinoma, which is uncommon in children. Patients with gastric adenocarcinoma typically experience vomiting, abdominal pain, anemia, and weight loss. We present a case of a 14.5-year-old male with gastric adenocarcinoma that manifested as left hip pain, epigastric pain, dysphagia, weight loss, and melena. Physical exam revealed cachexia, jaundice, a palpable epigastric mass, palpable liver edge, and left hip tenderness. Laboratory tests showed microcytic anemia, increase in carcinoembryonic antigen (CEA), and abnormal liver function test. Endoscopy revealed a cardial mass extending to the esophagus involving the gastroesophageal junction (GEJ). The gastric mass biopsy was consistent with invasive, moderately-differentiated gastric adenocarcinoma, which confirmed the diagnosis of gastric adenocarcinoma. Furthermore, a bone isotope scan revealed mildly hypervascular active bone pathology within the left proximal femur implying possible metastasis. Computed tomography scans and barium swallow were also helpful in supporting the diagnosis. Our case report emphasizes that gastric adenocarcinoma should be encompassed in the differential diagnosis of pediatric patients with hip pain.</description><subject>Abdomen</subject><subject>Anemia</subject><subject>Antigens</subject><subject>Barium</subject><subject>Biomarkers</subject><subject>Biopsy</subject><subject>Blood</subject><subject>Case reports</subject><subject>Dysphagia</subject><subject>Endoscopy</subject><subject>Esophagus</subject><subject>Families & family life</subject><subject>Family medical history</subject><subject>Gastric cancer</subject><subject>Gastroenterology</subject><subject>Gastrointestinal surgery</subject><subject>Hemoglobin</subject><subject>Liver</subject><subject>Lymphatic system</subject><subject>Medical diagnosis</subject><subject>Medical prognosis</subject><subject>Metastasis</subject><subject>Mutation</subject><subject>Oncology</subject><subject>Ostomy</subject><subject>Pain</subject><subject>Patients</subject><subject>Pediatrics</subject><subject>Young adults</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpVkEFLAzEQhYMottTePMuCV7dOkk2yuQilaBUK9qDnkGaTmtLu1mRX8N8b21rqYXgD83jz-BC6xjASgsl70wXbxREtOMNnqE8wL_MSl8X5yd5DwxhXAIBBEBBwiXqUl5IxCn0k5rbyug3eZFMddzqubN0YHYyvm43O5sFGW7e-XmbjmD37bTbXvr5CF06vox0edIDenx7fJs_57HX6MhnPckM4b3MLhQQuBFiJS0ao4wW1jpUyLVUlnTDFgso0wggtDDakcoRjK7kxklNHB-hhn7vtFhtbmdQk6LXaBr_R4Vs12qv_l9p_qGXzpaSUGLBMAbeHgNB8dja2atV0oU6dFRGSUkwYQHLd7V0mNDEG644fMKhf0mpPWu1IJ_vNaauj-Y8r_QEBHHoj</recordid><startdate>20230205</startdate><enddate>20230205</enddate><creator>Sobh, Mohammed J</creator><creator>Al Jayyousi, Obada A</creator><creator>Mahasna, Ahmad</creator><creator>Sobh, Rawan J</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope></search><sort><creationdate>20230205</creationdate><title>Pediatric Gastric Adenocarcinoma Presenting As Hip Pain</title><author>Sobh, Mohammed J ; Al Jayyousi, Obada A ; Mahasna, Ahmad ; Sobh, Rawan J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c266t-e04906770e918523f643ef589f64dd9f7c4b394b37c7a7c1c2df261e96cc963f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Abdomen</topic><topic>Anemia</topic><topic>Antigens</topic><topic>Barium</topic><topic>Biomarkers</topic><topic>Biopsy</topic><topic>Blood</topic><topic>Case reports</topic><topic>Dysphagia</topic><topic>Endoscopy</topic><topic>Esophagus</topic><topic>Families & family life</topic><topic>Family medical history</topic><topic>Gastric cancer</topic><topic>Gastroenterology</topic><topic>Gastrointestinal surgery</topic><topic>Hemoglobin</topic><topic>Liver</topic><topic>Lymphatic system</topic><topic>Medical diagnosis</topic><topic>Medical prognosis</topic><topic>Metastasis</topic><topic>Mutation</topic><topic>Oncology</topic><topic>Ostomy</topic><topic>Pain</topic><topic>Patients</topic><topic>Pediatrics</topic><topic>Young adults</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sobh, Mohammed J</creatorcontrib><creatorcontrib>Al Jayyousi, Obada A</creatorcontrib><creatorcontrib>Mahasna, Ahmad</creatorcontrib><creatorcontrib>Sobh, Rawan J</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sobh, Mohammed J</au><au>Al Jayyousi, Obada A</au><au>Mahasna, Ahmad</au><au>Sobh, Rawan J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pediatric Gastric Adenocarcinoma Presenting As Hip Pain</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2023-02-05</date><risdate>2023</risdate><volume>15</volume><issue>2</issue><spage>e34651</spage><pages>e34651-</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>The third most lethal cancer in the world is gastric adenocarcinoma, which is uncommon in children. Patients with gastric adenocarcinoma typically experience vomiting, abdominal pain, anemia, and weight loss. We present a case of a 14.5-year-old male with gastric adenocarcinoma that manifested as left hip pain, epigastric pain, dysphagia, weight loss, and melena. Physical exam revealed cachexia, jaundice, a palpable epigastric mass, palpable liver edge, and left hip tenderness. Laboratory tests showed microcytic anemia, increase in carcinoembryonic antigen (CEA), and abnormal liver function test. Endoscopy revealed a cardial mass extending to the esophagus involving the gastroesophageal junction (GEJ). The gastric mass biopsy was consistent with invasive, moderately-differentiated gastric adenocarcinoma, which confirmed the diagnosis of gastric adenocarcinoma. Furthermore, a bone isotope scan revealed mildly hypervascular active bone pathology within the left proximal femur implying possible metastasis. Computed tomography scans and barium swallow were also helpful in supporting the diagnosis. Our case report emphasizes that gastric adenocarcinoma should be encompassed in the differential diagnosis of pediatric patients with hip pain.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>36895530</pmid><doi>10.7759/cureus.34651</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Abdomen Anemia Antigens Barium Biomarkers Biopsy Blood Case reports Dysphagia Endoscopy Esophagus Families & family life Family medical history Gastric cancer Gastroenterology Gastrointestinal surgery Hemoglobin Liver Lymphatic system Medical diagnosis Medical prognosis Metastasis Mutation Oncology Ostomy Pain Patients Pediatrics Young adults |
| title | Pediatric Gastric Adenocarcinoma Presenting As Hip Pain |
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