Concerted Differential Changes of Helical Dynamics and Packing upon Ligand Occupancy in a Bacterial Chemoreceptor

Transmembrane receptors are central components of the chemosensory systems by which motile bacteria detect and respond to chemical gradients. An attractant bound to the receptor periplasmic domain generates conformational signals that regulate a histidine kinase interacting with its cytoplasmic doma...

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Veröffentlicht in:	ACS chemical biology 2021-11, Vol.16 (11), p.2472-2480
Hauptverfasser:	Gordon, Jesse B, Hoffman, Mikaila C, Troiano, Julianne M, Li, Mingshan, Hazelbauer, Gerald L, Schlau-Cohen, Gabriela S
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Proteins - metabolism Escherichia coli - metabolism Fluorescence Resonance Energy Transfer Ligands Protein Conformation Signal Transduction
Online-Zugang:	Volltext
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