A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine

Pfs230 domain 1 (Pfs230D1) is an advanced malaria transmission-blocking vaccine antigen demonstrating high functional activity in clinical trials. However, the structural and functional correlates of transmission-blocking activity are not defined. Here, we characterized a panel of human monoclonal a...

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Veröffentlicht in:	Immunity (Cambridge, Mass.) Mass.), 2023-02, Vol.56 (2), p.433-443.e5
Hauptverfasser:	Tang, Wai Kwan, Coelho, Camila H., Miura, Kazutoyo, Nguemwo Tentokam, Bergeline C., Salinas, Nichole D., Narum, David L., Healy, Sara A., Sagara, Issaka, Long, Carole A., Duffy, Patrick E., Tolia, Niraj H.
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES Antibodies, Neutralizing Antibodies, Viral Antigens Epitopes Humans Immunology Malaria Vaccines
Online-Zugang:	Volltext
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