HLA-DR expression on monocytes and outcome of anti-CD19 CAR T-cell therapy for large B-cell lymphoma

•Low prelymphodepletion mHLA-DR correlates with older age, poorer ECOG performance status, higher tumor burden, and systemic inflammation.•Low prelymphodepletion mHLA-DR is associated with poorer duration of response and survival in LBCL treated with anti-CD19 CAR T cells. [Display omitted] Despite...

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Veröffentlicht in:	Blood advances 2023-03, Vol.7 (5), p.744-755
Hauptverfasser:	Bourbon, Estelle, Sesques, Pierre, Gossez, Morgane, Tordo, Jérémie, Ferrant, Emmanuelle, Safar, Violaine, Wallet, Florent, Aussedat, Guillaume, Maarek, Alizée, Bouafia, Fadhela, Karlin, Lionel, Ghergus, Dana, Golfier, Camille, Lequeu, Hélène, Lazareth, Anne, Schwiertz, Vérane, Viel, Sébastien, Idlhaj, Maryam, Ghesquières, Hervé, Monneret, Guillaume, Bachy, Emmanuel, Venet, Fabienne
Format:	Artikel
Sprache:	eng
Schlagworte:	HLA-DR Antigens Humans Immunobiology and Immunotherapy Immunotherapy, Adoptive - adverse effects Life Sciences Lymphoma, Large B-Cell, Diffuse - therapy Monocytes Neoplasm Recurrence, Local
Online-Zugang:	Volltext
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