Prediction of Noninvasive Ventilation Failure in a Mixed Population Visiting the Emergency Department in a Tertiary Care Center in India
Noninvasive ventilation (NIV) is an established first-line treatment of acute respiratory failure both in emergency departments (ED) and intensive care unit (ICU) settings. It is however not always successful. Prospective, observational study was done among patients above 18 years presenting with ac...
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| Veröffentlicht in: | Indian journal of critical care medicine 2022-10, Vol.26 (10), p.1115-1119 |
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| creator | Mathen, Prannoy George Kumar, Kp Gireesh Mohan, Naveen Sreekrishnan, T P Nair, Sabarish B Krishnan, Arun Kumar Prasad S, Bharath Ahamed D, Riaz Theresa, Manna Maria Kathyayini, V R Vivek, U |
| description | Noninvasive ventilation (NIV) is an established first-line treatment of acute respiratory failure both in emergency departments (ED) and intensive care unit (ICU) settings. It is however not always successful.
Prospective, observational study was done among patients above 18 years presenting with acute respiratory failure initiated on NIV. Patients were placed in one of two groups covering successful NIV treatment and NIV failure. Two groups were compared on four variables: initial respiratory rate (RR), initial high-sensitivity C-reactive protein (hs-CRP), PaO
/FiO
ratio (p/f ratio), and heart rate, acidosis, consciousness, oxygenation, and respiratory rate (HACOR) score at the end of 1 hour of initiation of NIV.
A total of 104 patients fulfilling the inclusion criteria were included in the study, of which 55 (52.88%) were exclusively treated with NIV (NIV success group), and 49 (47.11%) required endotracheal intubation and mechanical ventilation (NIV failure group). Noninvasive ventilation failure group had a higher mean initial RR compared with NIV success group (40.65 ± 3.88 vs 31.98 ± 3.15, |
| doi_str_mv | 10.5005/jp-journals-10071-24338 |
| format | Article |
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Prospective, observational study was done among patients above 18 years presenting with acute respiratory failure initiated on NIV. Patients were placed in one of two groups covering successful NIV treatment and NIV failure. Two groups were compared on four variables: initial respiratory rate (RR), initial high-sensitivity C-reactive protein (hs-CRP), PaO
/FiO
ratio (p/f ratio), and heart rate, acidosis, consciousness, oxygenation, and respiratory rate (HACOR) score at the end of 1 hour of initiation of NIV.
A total of 104 patients fulfilling the inclusion criteria were included in the study, of which 55 (52.88%) were exclusively treated with NIV (NIV success group), and 49 (47.11%) required endotracheal intubation and mechanical ventilation (NIV failure group). Noninvasive ventilation failure group had a higher mean initial RR compared with NIV success group (40.65 ± 3.88 vs 31.98 ± 3.15,
<0.001). Mean initial PaO
/FiO
ratio was also significantly lower in the NIV failure group (184.57 ± 50.33 vs 277.29 ± 34.70,
<0.001). Odds ratio for successful NIV treatment with a high initial RR was 0.503 (95% confidence interval (CI), 0.390-0.649) and with a higher initial PaO
/FiO
ratio was 1.053 (95% CI: 1.032-1.071 and with a HACOR score of >5 at the end of 1 hour of initiation of NIV was highly associated with NIV failure (
<0.001). A high initial level of hs-CRP was 0.949 (95% CI: 0.927-0.970).
Noninvasive ventilation failure could be predicted with information available at presentation in ED, and unnecessary delay in endotracheal intubation could possibly be prevented.
Mathen PG, Kumar KPG, Mohan N, Sreekrishnan TP, Nair SB, Krishnan AK,
. Prediction of Noninvasive Ventilation Failure in a Mixed Population Visiting the Emergency Department in a Tertiary Care Center in India. Indian J Crit Care Med 2022;26(10):1115-1119.</description><identifier>ISSN: 0972-5229</identifier><identifier>EISSN: 1998-359X</identifier><identifier>DOI: 10.5005/jp-journals-10071-24338</identifier><identifier>PMID: 36876205</identifier><language>eng</language><publisher>India: Jaypee Brothers Medical Publishers</publisher><subject>Original</subject><ispartof>Indian journal of critical care medicine, 2022-10, Vol.26 (10), p.1115-1119</ispartof><rights>Copyright © 2022; Jaypee Brothers Medical Publishers (P) Ltd.</rights><rights>Copyright © 2022; Jaypee Brothers Medical Publishers (P) Ltd. 2022</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c417t-73c17d833a740af6be3b7b330467ef2bd391e9ca6cf139abba96ff60fd42ae2a3</citedby><cites>FETCH-LOGICAL-c417t-73c17d833a740af6be3b7b330467ef2bd391e9ca6cf139abba96ff60fd42ae2a3</cites><orcidid>0000-0002-7539-9285 ; 0000-0002-9367-5714 ; 0000-0002-9856-1193 ; 0000-0001-8006-9427 ; 0000-0002-6759-0549 ; 0000-0002-3741-064X ; 0000-0001-6333-4479 ; 0000-0002-3553-5211 ; 0000-0002-7291-6160 ; 0000-0002-4175-0102 ; 0000-0003-1327-7693</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983674/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983674/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36876205$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mathen, Prannoy George</creatorcontrib><creatorcontrib>Kumar, Kp Gireesh</creatorcontrib><creatorcontrib>Mohan, Naveen</creatorcontrib><creatorcontrib>Sreekrishnan, T P</creatorcontrib><creatorcontrib>Nair, Sabarish B</creatorcontrib><creatorcontrib>Krishnan, Arun Kumar</creatorcontrib><creatorcontrib>Prasad S, Bharath</creatorcontrib><creatorcontrib>Ahamed D, Riaz</creatorcontrib><creatorcontrib>Theresa, Manna Maria</creatorcontrib><creatorcontrib>Kathyayini, V R</creatorcontrib><creatorcontrib>Vivek, U</creatorcontrib><title>Prediction of Noninvasive Ventilation Failure in a Mixed Population Visiting the Emergency Department in a Tertiary Care Center in India</title><title>Indian journal of critical care medicine</title><addtitle>Indian J Crit Care Med</addtitle><description>Noninvasive ventilation (NIV) is an established first-line treatment of acute respiratory failure both in emergency departments (ED) and intensive care unit (ICU) settings. It is however not always successful.
Prospective, observational study was done among patients above 18 years presenting with acute respiratory failure initiated on NIV. Patients were placed in one of two groups covering successful NIV treatment and NIV failure. Two groups were compared on four variables: initial respiratory rate (RR), initial high-sensitivity C-reactive protein (hs-CRP), PaO
/FiO
ratio (p/f ratio), and heart rate, acidosis, consciousness, oxygenation, and respiratory rate (HACOR) score at the end of 1 hour of initiation of NIV.
A total of 104 patients fulfilling the inclusion criteria were included in the study, of which 55 (52.88%) were exclusively treated with NIV (NIV success group), and 49 (47.11%) required endotracheal intubation and mechanical ventilation (NIV failure group). Noninvasive ventilation failure group had a higher mean initial RR compared with NIV success group (40.65 ± 3.88 vs 31.98 ± 3.15,
<0.001). Mean initial PaO
/FiO
ratio was also significantly lower in the NIV failure group (184.57 ± 50.33 vs 277.29 ± 34.70,
<0.001). Odds ratio for successful NIV treatment with a high initial RR was 0.503 (95% confidence interval (CI), 0.390-0.649) and with a higher initial PaO
/FiO
ratio was 1.053 (95% CI: 1.032-1.071 and with a HACOR score of >5 at the end of 1 hour of initiation of NIV was highly associated with NIV failure (
<0.001). A high initial level of hs-CRP was 0.949 (95% CI: 0.927-0.970).
Noninvasive ventilation failure could be predicted with information available at presentation in ED, and unnecessary delay in endotracheal intubation could possibly be prevented.
Mathen PG, Kumar KPG, Mohan N, Sreekrishnan TP, Nair SB, Krishnan AK,
. Prediction of Noninvasive Ventilation Failure in a Mixed Population Visiting the Emergency Department in a Tertiary Care Center in India. Indian J Crit Care Med 2022;26(10):1115-1119.</description><subject>Original</subject><issn>0972-5229</issn><issn>1998-359X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNpVkc1u1DAUhS0EokPhFcBLNgH_JHa8QUJDC5UKdFEqdtZNcjP1KLGDnYzoG_DYuDPTClaWfO45PtcfIW84e1cxVr3fTsU2LNHDkArOmOaFKKWsn5AVN6YuZGV-PiUrZrQoKiHMCXmR0pYxoYzgz8mJVLVWglUr8ucqYufa2QVPQ0-_Be_8DpLbIb1BP7sB9tI5uGGJSJ2nQL-639jRqzAtR_XGJTc7v6HzLdKzEeMGfXtHP-EEcR5zzMF3jXF2EO_oGnLUOt9jvFcufOfgJXnW523w1fE8JT_Oz67XX4rL758v1h8vi7bkei60bLnuailBlwx61aBsdCMlK5XGXjSdNBxNC6rtuTTQNGBU3yvWd6UAFCBPyYdD7rQ0I3ZtbhFhsFN0Y65mAzj7v-Ldrd2Enc3_KpUuc8DbY0AMvxZMsx1danEYwGNYkhW6lrquJRN5VB9G2xhSitg_PsOZvedot5N94Gj3HO2eY3a-_rflo-8BnPwL8yyhYA</recordid><startdate>20221001</startdate><enddate>20221001</enddate><creator>Mathen, Prannoy George</creator><creator>Kumar, Kp Gireesh</creator><creator>Mohan, Naveen</creator><creator>Sreekrishnan, T P</creator><creator>Nair, Sabarish B</creator><creator>Krishnan, Arun Kumar</creator><creator>Prasad S, Bharath</creator><creator>Ahamed D, Riaz</creator><creator>Theresa, Manna Maria</creator><creator>Kathyayini, V R</creator><creator>Vivek, U</creator><general>Jaypee Brothers Medical Publishers</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-7539-9285</orcidid><orcidid>https://orcid.org/0000-0002-9367-5714</orcidid><orcidid>https://orcid.org/0000-0002-9856-1193</orcidid><orcidid>https://orcid.org/0000-0001-8006-9427</orcidid><orcidid>https://orcid.org/0000-0002-6759-0549</orcidid><orcidid>https://orcid.org/0000-0002-3741-064X</orcidid><orcidid>https://orcid.org/0000-0001-6333-4479</orcidid><orcidid>https://orcid.org/0000-0002-3553-5211</orcidid><orcidid>https://orcid.org/0000-0002-7291-6160</orcidid><orcidid>https://orcid.org/0000-0002-4175-0102</orcidid><orcidid>https://orcid.org/0000-0003-1327-7693</orcidid></search><sort><creationdate>20221001</creationdate><title>Prediction of Noninvasive Ventilation Failure in a Mixed Population Visiting the Emergency Department in a Tertiary Care Center in India</title><author>Mathen, Prannoy George ; Kumar, Kp Gireesh ; Mohan, Naveen ; Sreekrishnan, T P ; Nair, Sabarish B ; Krishnan, Arun Kumar ; Prasad S, Bharath ; Ahamed D, Riaz ; Theresa, Manna Maria ; Kathyayini, V R ; Vivek, U</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c417t-73c17d833a740af6be3b7b330467ef2bd391e9ca6cf139abba96ff60fd42ae2a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Original</topic><toplevel>online_resources</toplevel><creatorcontrib>Mathen, Prannoy George</creatorcontrib><creatorcontrib>Kumar, Kp Gireesh</creatorcontrib><creatorcontrib>Mohan, Naveen</creatorcontrib><creatorcontrib>Sreekrishnan, T P</creatorcontrib><creatorcontrib>Nair, Sabarish B</creatorcontrib><creatorcontrib>Krishnan, Arun Kumar</creatorcontrib><creatorcontrib>Prasad S, Bharath</creatorcontrib><creatorcontrib>Ahamed D, Riaz</creatorcontrib><creatorcontrib>Theresa, Manna Maria</creatorcontrib><creatorcontrib>Kathyayini, V R</creatorcontrib><creatorcontrib>Vivek, U</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Indian journal of critical care medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mathen, Prannoy George</au><au>Kumar, Kp Gireesh</au><au>Mohan, Naveen</au><au>Sreekrishnan, T P</au><au>Nair, Sabarish B</au><au>Krishnan, Arun Kumar</au><au>Prasad S, Bharath</au><au>Ahamed D, Riaz</au><au>Theresa, Manna Maria</au><au>Kathyayini, V R</au><au>Vivek, U</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prediction of Noninvasive Ventilation Failure in a Mixed Population Visiting the Emergency Department in a Tertiary Care Center in India</atitle><jtitle>Indian journal of critical care medicine</jtitle><addtitle>Indian J Crit Care Med</addtitle><date>2022-10-01</date><risdate>2022</risdate><volume>26</volume><issue>10</issue><spage>1115</spage><epage>1119</epage><pages>1115-1119</pages><issn>0972-5229</issn><eissn>1998-359X</eissn><abstract>Noninvasive ventilation (NIV) is an established first-line treatment of acute respiratory failure both in emergency departments (ED) and intensive care unit (ICU) settings. It is however not always successful.
Prospective, observational study was done among patients above 18 years presenting with acute respiratory failure initiated on NIV. Patients were placed in one of two groups covering successful NIV treatment and NIV failure. Two groups were compared on four variables: initial respiratory rate (RR), initial high-sensitivity C-reactive protein (hs-CRP), PaO
/FiO
ratio (p/f ratio), and heart rate, acidosis, consciousness, oxygenation, and respiratory rate (HACOR) score at the end of 1 hour of initiation of NIV.
A total of 104 patients fulfilling the inclusion criteria were included in the study, of which 55 (52.88%) were exclusively treated with NIV (NIV success group), and 49 (47.11%) required endotracheal intubation and mechanical ventilation (NIV failure group). Noninvasive ventilation failure group had a higher mean initial RR compared with NIV success group (40.65 ± 3.88 vs 31.98 ± 3.15,
<0.001). Mean initial PaO
/FiO
ratio was also significantly lower in the NIV failure group (184.57 ± 50.33 vs 277.29 ± 34.70,
<0.001). Odds ratio for successful NIV treatment with a high initial RR was 0.503 (95% confidence interval (CI), 0.390-0.649) and with a higher initial PaO
/FiO
ratio was 1.053 (95% CI: 1.032-1.071 and with a HACOR score of >5 at the end of 1 hour of initiation of NIV was highly associated with NIV failure (
<0.001). A high initial level of hs-CRP was 0.949 (95% CI: 0.927-0.970).
Noninvasive ventilation failure could be predicted with information available at presentation in ED, and unnecessary delay in endotracheal intubation could possibly be prevented.
Mathen PG, Kumar KPG, Mohan N, Sreekrishnan TP, Nair SB, Krishnan AK,
. Prediction of Noninvasive Ventilation Failure in a Mixed Population Visiting the Emergency Department in a Tertiary Care Center in India. Indian J Crit Care Med 2022;26(10):1115-1119.</abstract><cop>India</cop><pub>Jaypee Brothers Medical Publishers</pub><pmid>36876205</pmid><doi>10.5005/jp-journals-10071-24338</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0002-7539-9285</orcidid><orcidid>https://orcid.org/0000-0002-9367-5714</orcidid><orcidid>https://orcid.org/0000-0002-9856-1193</orcidid><orcidid>https://orcid.org/0000-0001-8006-9427</orcidid><orcidid>https://orcid.org/0000-0002-6759-0549</orcidid><orcidid>https://orcid.org/0000-0002-3741-064X</orcidid><orcidid>https://orcid.org/0000-0001-6333-4479</orcidid><orcidid>https://orcid.org/0000-0002-3553-5211</orcidid><orcidid>https://orcid.org/0000-0002-7291-6160</orcidid><orcidid>https://orcid.org/0000-0002-4175-0102</orcidid><orcidid>https://orcid.org/0000-0003-1327-7693</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Original |
| title | Prediction of Noninvasive Ventilation Failure in a Mixed Population Visiting the Emergency Department in a Tertiary Care Center in India |
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