Protective Effects of Crocin Against Methotrexate-Induced Hepatotoxicity in Adult Male Albino Rats: Histological, Immunohistochemical, and Biochemical Study

Among the many known adverse effects of methotrexate (MTX), hepatotoxicity stands out as a major drawback that limits its therapeutic applicability. There is growing evidence that crocin has antioxidant, anti-hyperglycemic, cardioprotective, and anti-inflammatory effects. This study's aim is to...

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Veröffentlicht in:	Curēus (Palo Alto, CA) CA), 2023-01, Vol.15 (1), p.e34468-e34468
Hauptverfasser:	AbdelKader, Ghada, Abdelaziz, Eman Z, Hassan, Ranya, Greish, Sahar M, Abogresha, Noha M, Sultan, Basma O, Yousef, Einas M, Morsi, Shereen
Format:	Artikel
Sprache:	eng
Schlagworte:	Anatomy Antioxidants Apoptosis Cytotoxicity Dehydrogenases Deoxyribonucleic acid DNA Enzymes Experiments Homocysteine Liver cirrhosis Oxidative stress Pathology Proteins
Online-Zugang:	Volltext
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