The Function of Retinal Thickness and Microvascular Alterations in the Diagnosis of Systemic Sclerosis

In this study, we aim to investigate retinal thickness (RT) and superficial vascular density (SVD) differences between patients with systemic sclerosis (SSc) and healthy controls (HCs) by optical coherence tomography angiography (OCTA). Sixteen patients with a definitive SSc diagnosis without clinic...

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Veröffentlicht in:	BioMed research international 2023, Vol.2023 (1), p.1805938-1805938
Hauptverfasser:	Fang, Xia, Yu, Shujiao, Peng, Yilin, Huang, Bozhi, Kang, Min, Xiong, Jiangbiao, Luo, Ting, Wu, Rui, Shao, Yi
Format:	Artikel
Sprache:	eng
Schlagworte:	Acuity Angiography Blood Complications and side effects CT imaging Diabetes mellitus Diabetic Retinopathy Diagnosis Disease Humans Immunology Macula Lutea Medical examination Microcirculation disorders Microvasculature Patients Retina Retinal Diseases Retinopathy Rheumatology Risk factors Scleroderma Scleroderma (Disease) Scleroderma, Systemic Systemic scleroderma Systemic sclerosis Thickness Visual acuity
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Zusammenfassung:	In this study, we aim to investigate retinal thickness (RT) and superficial vascular density (SVD) differences between patients with systemic sclerosis (SSc) and healthy controls (HCs) by optical coherence tomography angiography (OCTA). Sixteen patients with a definitive SSc diagnosis without clinical signs of retinopathy and 16 normal control subjects were recruited. All individuals underwent OCTA scanning to assess macular RT and SVD. We divided each image into nine subregions as the early treatment diabetic retinopathy study (ETDRS). Visual acuity (VA) was considerably different between patients with SSc (32 eyes) and control subjects (32 eyes) (p
ISSN:	2314-6133 2314-6141
DOI:	10.1155/2023/1805938