Zebrafish Models to Study Ectopic Calcification and Calcium-Associated Pathologies

Ectopic calcification refers to the pathological accumulation of calcium ions in soft tissues and is often the result of a dysregulated action or disrupted function of proteins involved in extracellular matrix mineralization. While the mouse has traditionally been the go-to model organism for the st...

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Veröffentlicht in:	International journal of molecular sciences 2023-02, Vol.24 (4), p.3366
Hauptverfasser:	Santos, João M A, Laizé, Vincent, Gavaia, Paulo J, Conceição, Natércia, Cancela, M Leonor
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Animals Bone growth Calcification Calcification (ectopic) Calcification, Physiologic Calcinosis - metabolism Calcium Calcium - metabolism Calcium ions Calcium, Dietary - metabolism Cartilage Danio rerio DNA damage Extracellular matrix Extracellular Matrix - metabolism Genetic disorders Genetic engineering Genotype & phenotype Heart Homeostasis Humans Kidney diseases Medical research Medicine, Experimental Metabolism Metastasis Mice Mineralization Mutants Mutation Osteogenesis Pathophysiology Phenotypes Proteins Review Soft tissues Zebrafish Zebrafish - genetics
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