Pathogenicity of Type I Interferons in Mycobacterium tuberculosis

Tuberculosis (TB) is a leading cause of mortality due to infectious disease and rates have increased during the emergence of COVID-19, but many of the factors determining disease severity and progression remain unclear. Type I Interferons (IFNs) have diverse effector functions that regulate innate a...

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Veröffentlicht in:	International journal of molecular sciences 2023-02, Vol.24 (4), p.3919
Hauptverfasser:	Mundra, Akaash, Yegiazaryan, Aram, Karsian, Haig, Alsaigh, Dijla, Bonavida, Victor, Frame, Mitchell, May, Nicole, Gargaloyan, Areg, Abnousian, Arbi, Venketaraman, Vishwanath
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive immunity Alveoli Antigens Bacteria Chemokines Comorbidity Coronaviruses COVID-19 COVID-19 vaccines Cytokines Dendritic cells Disease transmission GMP synthase Granulomas HIV Human immunodeficiency virus Humans Immunity, Innate Indoor air quality Infections Infectious diseases Interferon Interferon Type I - metabolism Interferons - metabolism Leukocytes (neutrophilic) Lymphatic system Lymphocytes Macrophages Malnutrition Microorganisms Mycobacterium tuberculosis - metabolism Pandemics Pathogenesis Pathogenicity Pathogens Patients Review Risk factors Socioeconomic factors Tuberculosis Tumor necrosis factor-TNF Viral infections Virulence
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