Transurethral Incision of the Bladder Neck with or without Additional Procedure Resumes Spontaneous Voiding in Female Voiding Dysfunction-A Long-Term Retrospective Follow-Up
This study evaluated the long-term effectiveness of transurethral incision of the bladder neck (TUI-BN) with or without an additional procedure for female voiding dysfunction. Women with voiding difficulty who underwent TUI-BN in the last 12 years were included. All patients underwent a videourodyna...
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description | This study evaluated the long-term effectiveness of transurethral incision of the bladder neck (TUI-BN) with or without an additional procedure for female voiding dysfunction.
Women with voiding difficulty who underwent TUI-BN in the last 12 years were included. All patients underwent a videourodynamics study (VUDS) at baseline and after TUI-BN. A successful outcome was defined as having a voiding efficiency (VE) increase by ≥50% after treatment. Patients with insufficient improvement were chosen for repeated TUI-BN, urethral onabotulinumtoxinA injection, or transurethral external sphincter incision (TUI-ES). The current voiding status, surgical complications, and additional surgeries were evaluated.
A total of 102 women with VUDS evidence of a narrow bladder neck during voiding were enrolled. The long-term success rate of the first TUI-BN was 29.4% (30/102) and increased to 66.7% (34/51) after combining TUI-BN and an additional procedure. The overall long-term success rates were 74.6% in women with detrusor underactivity (DU), 52.0% in detrusor overactivity and low contractility, 50.0% in bladder neck obstruction, 20.0% in hypersensitive bladder, and 75% in stable bladder (
= 0.022). Patients with a lower maximum flow rate (Qmax), (
= 0.002), lower voided volume (
< 0.001), lower corrected Qmax (
< 0.001), lower ladder contractility index (
= 0.003), lower voiding efficiency (
< 0.001), but larger post-void residual volume (
< 0.001) had a satisfactory surgical outcome. Spontaneous voiding was achieved in 66 (64.7%) patients, de novo urinary incontinence in 21 (20.6%), and vesicovaginal fistula in 4 (3.9%), all were repaired.
TUI-BN alone or in combination with an additional procedure was safe, effective, and durable in patients with DU to resume spontaneous voiding. |
doi_str_mv | 10.3390/jcm12041514 |
format | Article |
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Women with voiding difficulty who underwent TUI-BN in the last 12 years were included. All patients underwent a videourodynamics study (VUDS) at baseline and after TUI-BN. A successful outcome was defined as having a voiding efficiency (VE) increase by ≥50% after treatment. Patients with insufficient improvement were chosen for repeated TUI-BN, urethral onabotulinumtoxinA injection, or transurethral external sphincter incision (TUI-ES). The current voiding status, surgical complications, and additional surgeries were evaluated.
A total of 102 women with VUDS evidence of a narrow bladder neck during voiding were enrolled. The long-term success rate of the first TUI-BN was 29.4% (30/102) and increased to 66.7% (34/51) after combining TUI-BN and an additional procedure. The overall long-term success rates were 74.6% in women with detrusor underactivity (DU), 52.0% in detrusor overactivity and low contractility, 50.0% in bladder neck obstruction, 20.0% in hypersensitive bladder, and 75% in stable bladder (
= 0.022). Patients with a lower maximum flow rate (Qmax), (
= 0.002), lower voided volume (
< 0.001), lower corrected Qmax (
< 0.001), lower ladder contractility index (
= 0.003), lower voiding efficiency (
< 0.001), but larger post-void residual volume (
< 0.001) had a satisfactory surgical outcome. Spontaneous voiding was achieved in 66 (64.7%) patients, de novo urinary incontinence in 21 (20.6%), and vesicovaginal fistula in 4 (3.9%), all were repaired.
TUI-BN alone or in combination with an additional procedure was safe, effective, and durable in patients with DU to resume spontaneous voiding.</description><identifier>ISSN: 2077-0383</identifier><identifier>EISSN: 2077-0383</identifier><identifier>DOI: 10.3390/jcm12041514</identifier><identifier>PMID: 36836048</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Bladder ; Bladder diseases ; Botulinum toxin ; Care and treatment ; Clinical medicine ; Confidence intervals ; Demographic aspects ; Fistula ; Regression analysis ; Surgery ; Surgical outcomes ; Urinary incontinence ; Urogenital system</subject><ispartof>Journal of clinical medicine, 2023-02, Vol.12 (4), p.1514</ispartof><rights>COPYRIGHT 2023 MDPI AG</rights><rights>2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2023 by the authors. 2023</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c476t-4580c611f6eef7bce37cab4741226c1a7e8c6d5aa485b9b6542394310a6384583</citedby><cites>FETCH-LOGICAL-c476t-4580c611f6eef7bce37cab4741226c1a7e8c6d5aa485b9b6542394310a6384583</cites><orcidid>0000-0001-5029-7007 ; 0000-0001-7165-4771</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964962/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964962/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36836048$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ong, Hueih-Ling</creatorcontrib><creatorcontrib>Kuo, Hann-Chorng</creatorcontrib><title>Transurethral Incision of the Bladder Neck with or without Additional Procedure Resumes Spontaneous Voiding in Female Voiding Dysfunction-A Long-Term Retrospective Follow-Up</title><title>Journal of clinical medicine</title><addtitle>J Clin Med</addtitle><description>This study evaluated the long-term effectiveness of transurethral incision of the bladder neck (TUI-BN) with or without an additional procedure for female voiding dysfunction.
Women with voiding difficulty who underwent TUI-BN in the last 12 years were included. All patients underwent a videourodynamics study (VUDS) at baseline and after TUI-BN. A successful outcome was defined as having a voiding efficiency (VE) increase by ≥50% after treatment. Patients with insufficient improvement were chosen for repeated TUI-BN, urethral onabotulinumtoxinA injection, or transurethral external sphincter incision (TUI-ES). The current voiding status, surgical complications, and additional surgeries were evaluated.
A total of 102 women with VUDS evidence of a narrow bladder neck during voiding were enrolled. The long-term success rate of the first TUI-BN was 29.4% (30/102) and increased to 66.7% (34/51) after combining TUI-BN and an additional procedure. The overall long-term success rates were 74.6% in women with detrusor underactivity (DU), 52.0% in detrusor overactivity and low contractility, 50.0% in bladder neck obstruction, 20.0% in hypersensitive bladder, and 75% in stable bladder (
= 0.022). Patients with a lower maximum flow rate (Qmax), (
= 0.002), lower voided volume (
< 0.001), lower corrected Qmax (
< 0.001), lower ladder contractility index (
= 0.003), lower voiding efficiency (
< 0.001), but larger post-void residual volume (
< 0.001) had a satisfactory surgical outcome. Spontaneous voiding was achieved in 66 (64.7%) patients, de novo urinary incontinence in 21 (20.6%), and vesicovaginal fistula in 4 (3.9%), all were repaired.
TUI-BN alone or in combination with an additional procedure was safe, effective, and durable in patients with DU to resume spontaneous voiding.</description><subject>Bladder</subject><subject>Bladder diseases</subject><subject>Botulinum toxin</subject><subject>Care and treatment</subject><subject>Clinical medicine</subject><subject>Confidence intervals</subject><subject>Demographic aspects</subject><subject>Fistula</subject><subject>Regression analysis</subject><subject>Surgery</subject><subject>Surgical outcomes</subject><subject>Urinary incontinence</subject><subject>Urogenital system</subject><issn>2077-0383</issn><issn>2077-0383</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNptklFv0zAUhSMEYtPYE-_IEi9IKMOOHdt5QSqDwqQKEHS8Wo5z07okdrCTTftR_EfctVQdwn6wde85n-Wjm2XPCb6gtMJvNqYnBWakJOxRdlpgIXJMJX18dD_JzmPc4LSkZAURT7MTyiXlmMnT7PcyaBenAOM66A5dOWOj9Q75Fo1rQO863TQQ0GcwP9GtHdfIh_vTTyOaNY0dkzj5vgZvoEkY9A3i1ENE3wfvRu3ATxH98LaxboWsQ3PodQeHyvu72E7ObCn5DC28W-VLCH2ijMHHAVLnBtDcd52_za-HZ9mTVncRzvfnWXY9_7C8_JQvvny8upwtcsMEH3NWSmw4IS0HaEVtgAqjayYYKQpuiBYgDW9KrZks66rmJStoxSjBmlOZzPQse7vjDlPdQ2PAjSkdNQTb63CnvLbqYcfZtVr5G1VVnFW8SIBXe0DwvyaIo-ptNNB1u0RUISTGvKgwT9KX_0g3fgop1KSqsKRUkHvgXrVK8SnrWp_eNVuomokSU1oWfMu6-I8q7QZ6a7yD1qb6A8PrncGkuGOA9vBHgtV2wNTRgCX1i-NYDtq_40T_AOOszPw</recordid><startdate>20230214</startdate><enddate>20230214</enddate><creator>Ong, Hueih-Ling</creator><creator>Kuo, Hann-Chorng</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-5029-7007</orcidid><orcidid>https://orcid.org/0000-0001-7165-4771</orcidid></search><sort><creationdate>20230214</creationdate><title>Transurethral Incision of the Bladder Neck with or without Additional Procedure Resumes Spontaneous Voiding in Female Voiding Dysfunction-A Long-Term Retrospective Follow-Up</title><author>Ong, Hueih-Ling ; Kuo, Hann-Chorng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c476t-4580c611f6eef7bce37cab4741226c1a7e8c6d5aa485b9b6542394310a6384583</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Bladder</topic><topic>Bladder diseases</topic><topic>Botulinum toxin</topic><topic>Care and treatment</topic><topic>Clinical medicine</topic><topic>Confidence intervals</topic><topic>Demographic aspects</topic><topic>Fistula</topic><topic>Regression analysis</topic><topic>Surgery</topic><topic>Surgical outcomes</topic><topic>Urinary incontinence</topic><topic>Urogenital system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ong, Hueih-Ling</creatorcontrib><creatorcontrib>Kuo, Hann-Chorng</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of clinical medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ong, Hueih-Ling</au><au>Kuo, Hann-Chorng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Transurethral Incision of the Bladder Neck with or without Additional Procedure Resumes Spontaneous Voiding in Female Voiding Dysfunction-A Long-Term Retrospective Follow-Up</atitle><jtitle>Journal of clinical medicine</jtitle><addtitle>J Clin Med</addtitle><date>2023-02-14</date><risdate>2023</risdate><volume>12</volume><issue>4</issue><spage>1514</spage><pages>1514-</pages><issn>2077-0383</issn><eissn>2077-0383</eissn><abstract>This study evaluated the long-term effectiveness of transurethral incision of the bladder neck (TUI-BN) with or without an additional procedure for female voiding dysfunction.
Women with voiding difficulty who underwent TUI-BN in the last 12 years were included. All patients underwent a videourodynamics study (VUDS) at baseline and after TUI-BN. A successful outcome was defined as having a voiding efficiency (VE) increase by ≥50% after treatment. Patients with insufficient improvement were chosen for repeated TUI-BN, urethral onabotulinumtoxinA injection, or transurethral external sphincter incision (TUI-ES). The current voiding status, surgical complications, and additional surgeries were evaluated.
A total of 102 women with VUDS evidence of a narrow bladder neck during voiding were enrolled. The long-term success rate of the first TUI-BN was 29.4% (30/102) and increased to 66.7% (34/51) after combining TUI-BN and an additional procedure. The overall long-term success rates were 74.6% in women with detrusor underactivity (DU), 52.0% in detrusor overactivity and low contractility, 50.0% in bladder neck obstruction, 20.0% in hypersensitive bladder, and 75% in stable bladder (
= 0.022). Patients with a lower maximum flow rate (Qmax), (
= 0.002), lower voided volume (
< 0.001), lower corrected Qmax (
< 0.001), lower ladder contractility index (
= 0.003), lower voiding efficiency (
< 0.001), but larger post-void residual volume (
< 0.001) had a satisfactory surgical outcome. Spontaneous voiding was achieved in 66 (64.7%) patients, de novo urinary incontinence in 21 (20.6%), and vesicovaginal fistula in 4 (3.9%), all were repaired.
TUI-BN alone or in combination with an additional procedure was safe, effective, and durable in patients with DU to resume spontaneous voiding.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>36836048</pmid><doi>10.3390/jcm12041514</doi><orcidid>https://orcid.org/0000-0001-5029-7007</orcidid><orcidid>https://orcid.org/0000-0001-7165-4771</orcidid><oa>free_for_read</oa></addata></record> |
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source | PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; EZB-FREE-00999 freely available EZB journals; PubMed Central |
subjects | Bladder Bladder diseases Botulinum toxin Care and treatment Clinical medicine Confidence intervals Demographic aspects Fistula Regression analysis Surgery Surgical outcomes Urinary incontinence Urogenital system |
title | Transurethral Incision of the Bladder Neck with or without Additional Procedure Resumes Spontaneous Voiding in Female Voiding Dysfunction-A Long-Term Retrospective Follow-Up |
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