Genome-wide CRISPRi screen identifies enhanced autolithotrophic phenotypes in acetogenic bacterium Eubacterium limosum

Acetogenic bacteria are a unique biocatalyst that highly promises to develop the sustainable bioconversion of carbon oxides (e.g., CO and CO ) into multicarbon biochemicals. Genotype-phenotype relationships are important for engineering their metabolic capability to enhance their biocatalytic perfor...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2023-02, Vol.120 (6), p.e2216244120-e2216244120
Hauptverfasser:	Shin, Jongoh, Bae, Jiyun, Lee, Hyeonsik, Kang, Seulgi, Jin, Sangrak, Song, Yoseb, Cho, Suhyung, Cho, Byung-Kwan
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetogenesis Acetoin Autotrophic Processes Bacteria Bioconversion Biological Sciences Biosynthesis Carbon dioxide Carbon Dioxide - metabolism CRISPR Eubacterium - genetics Eubacterium - metabolism Eurytium limosum Fitness Gene silencing Genes Genome, Bacterial Genomes Genotypes Growth rate Membrane proteins Membranes Metabolic engineering Phenotypes Protein biosynthesis
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