Deletion of Annexin A1 in Mice Upregulates the Expression of Its Receptor, Fpr2/3, and Reactivity to the AnxA1 Mimetic Peptide in Platelets

Annexin A1 (ANXA1) is an endogenous protein, which plays a central function in the modulation of inflammation. While the functions of ANXA1 and its exogenous peptidomimetics, -Acetyl 2-26 ANXA1-derived peptide (ANXA1 ), in the modulation of immunological responses of neutrophils and monocytes have b...

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Veröffentlicht in:	International journal of molecular sciences 2023-02, Vol.24 (4), p.3424
Hauptverfasser:	Zharkova, Olga, Salamah, Maryam F, Babak, Maria V, Rajan, Elanchezhian, Lim, Lina H K, Andrade, Frans, Gil, Cristiane D, Oliani, Sonia M, Moraes, Leonardo A, Vaiyapuri, Sakthivel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine diphosphate Amino acids Animals Annexin A1 - metabolism Annexins Biomarkers Blood clot Blood platelets Blood Platelets - metabolism Fibrinogen Flow cytometry Humans Immunology Inflammation Inflammation - metabolism Leukocytes (neutrophilic) Mice Monocytes Neutrophils Neutrophils - metabolism P-selectin Peptides Peptides - pharmacology Peptidomimetics Receptors, Formyl Peptide - metabolism Receptors, Lipoxin - metabolism Thrombosis
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