HER2 Expression in Bladder Cancer: A Focused View on Its Diagnostic, Prognostic, and Predictive Role

Bladder cancer (BC) is a heterogeneous disease from a molecular, morphological, and clinical standpoint. HER2 is a known oncogene involved in bladder carcinogenesis. Assessing HER2 overexpression as a result of its molecular changes in a routine pathology practice using immunohistochemistry might be...

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Veröffentlicht in:	International journal of molecular sciences 2023-02, Vol.24 (4), p.3720
Hauptverfasser:	Sanguedolce, Francesca, Zanelli, Magda, Palicelli, Andrea, Bisagni, Alessandra, Zizzo, Maurizio, Ascani, Stefano, Pedicillo, Maria Carmela, Cormio, Angelo, Falagario, Ugo Giovanni, Carrieri, Giuseppe, Cormio, Luigi
Format:	Artikel
Sprache:	eng
Schlagworte:	BCG BCG vaccines Biomarkers Biomarkers, Tumor - metabolism Bladder cancer Cancer therapies Carcinogenesis Carcinogens Chemotherapy Clinical trials Development and progression Epigenetics ErbB-2 protein Gene amplification Growth factors Humans Hybridization Immunohistochemistry Invasiveness Kinases Lesions Metastasis Muscles Prognosis Proteins Receptor, ErbB-2 - genetics Receptor, ErbB-2 - metabolism Review Therapeutic targets Tumors Urinary Bladder - pathology Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - pathology
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