Lithium in Cancer Therapy: Friend or Foe?

Lithium, a trace element important for fetal health and development, is considered a metal drug with a well-established clinical regime, economical production process, and a mature storage system. Several studies have shown that lithium affects tumor development by regulating inositol monophosphate...

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Veröffentlicht in:	Cancers 2023-02, Vol.15 (4), p.1095
Hauptverfasser:	Yang, Chunhao, Zhu, Bo, Zhan, Mingjie, Hua, Zi-Chun
Format:	Artikel
Sprache:	eng
Schlagworte:	Antitumor activity Apoptosis Autophagy Binding sites Bisphosphonates Cachexia Cancer Cancer therapies Care and treatment Catalysis Cell death Cell proliferation Chemotherapy Chloride Dosage and administration Drug resistance Enzymes Fetuses Glycogen Glycogen synthase kinase 3 Hypotheses Immune system Inositol monophosphate Kinases Leukemia Ligands Lithium Magnesium Melanoma Metabolism Phosphatase Phosphorylation Proteins Review Side effects Signal transduction Sodium Tumor cells Tumor necrosis factor-TNF Tumors
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