First detected geographical cluster of BoDV-1 encephalitis from same small village in two children: therapeutic considerations and epidemiological implications

Background The Borna disease virus (BoDV-1) is an emerging zoonotic virus causing severe and mostly fatal encephalitis in humans. Methods and Results A local cluster of fatal BoDV-1 encephalitis cases was detected in the same village three years apart affecting two children. While the first case was...

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Veröffentlicht in:	Infection 2023-10, Vol.51 (5), p.1383-1398
Hauptverfasser:	Grosse, Leonie, Lieftüchter, Victoria, Vollmuth, Yannik, Hoffmann, Florian, Olivieri, Martin, Reiter, Karl, Tacke, Moritz, Heinen, Florian, Borggraefe, Ingo, Osterman, Andreas, Forstner, Maria, Hübner, Johannes, von Both, Ulrich, Birzele, Lena, Rohlfs, Meino, Schomburg, Adrian, Böhmer, Merle M., Ruf, Viktoria, Cadar, Dániel, Muntau, Birgit, Pörtner, Kirsten, Tappe, Dennis
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral agents Borna disease Borna virus Clusters Diagnosis Encephalitis Epidemiology Family Medicine General Practice Genomes Health services Infectious Diseases Inflammation Internal Medicine Limbic system Medicine Medicine & Public Health Next-generation sequencing Olfactory nerve Patients Ribavirin Risk factors Saliva Sequences Therapy Villages Viruses Zoonoses
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