Minimal change prion retinopathy: Morphometric comparison of retinal and brain prion deposits in Creutzfeldt-Jakob disease

Sporadic Creutzfeldt-Jakob disease (sCJD) is the most commonly diagnosed human prion disease caused by the abnormal misfolding of the ‘cellular’ prion protein (PrPC) into the transmissible ‘scrapie-type’ prion form (PrPSc). Neuropathologic evaluation of brains with sCJD reveals abnormal PrPSc deposi...

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Veröffentlicht in:	Experimental eye research 2022-09, Vol.222, p.109172-109172, Article 109172
Hauptverfasser:	Goodwill, Vanessa S., Dryden, Ian, Choi, Jihee, De Lillo, Chiara, Soldau, Katrin, Llibre-Guerra, Jorge, Sanchez, Henry, Sigurdson, Christina J., Lin, Jonathan H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain Brain - pathology Creutzfeldt-Jakob Syndrome - diagnosis Creutzfeldt-Jakob Syndrome - metabolism Creutzfeldt-Jakob Syndrome - pathology Eye Gliosis - pathology Humans Immunohistochemistry Prion Prions Retina Retina - metabolism Retinal Diseases - pathology Spongiform encephalopathy sporadic Creutzfeldt-Jakob disease
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