Seroprevalence of Hepatitis B virus infection and associated factors among health care workers in Southern Ghana

•Seroprevalence of Hepatitis B virus among Ghanaian health care workers is 5.9%•Blood-borne infection prevention training reduces the odds of Hepatitis B infection•Hepatitis B infection rate is higher among lower-level health care workers The World Health Organization estimates that 37% of Hepatitis B Virus (HBV) infections among Health Care Workers (HCWs) are due to percutaneous occupational exposure to blood and body fluids. In Ghana, occupational exposures are rising; however, the burden of HBV infection in HCWs remains unknown. Our study estimated the prevalence of HBV surface antigens and associated factors among HCWs. We conducted a cross-sectional survey of 340 HCWs using a structured pretested questionnaire and screening for HBV surface antigens. Data were analyzed using SPSS version 20.0 with a level of significance set at