Differential cell composition and split epidermal differentiation in human palm, sole, and hip skin

Palmoplantar skin is structurally and functionally unique, but the transcriptional programs driving this specialization are unclear. Here, we use bulk and single-cell RNA sequencing of human palm, sole, and hip skin to describe the distinguishing characteristics of palmoplantar and non-palmoplantar...

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Veröffentlicht in:	Cell reports (Cambridge) 2023-01, Vol.42 (1), p.111994-111994, Article 111994
Hauptverfasser:	Wiedemann, Julie, Billi, Allison C., Bocci, Federico, Kashgari, Ghaidaa, Xing, Enze, Tsoi, Lam C., Meller, Leo, Swindell, William R., Wasikowski, Rachael, Xing, Xianying, Ma, Feiyang, Gharaee-Kermani, Mehrnaz, Kahlenberg, J. Michelle, Harms, Paul W., Maverakis, Emanual, Nie, Qing, Gudjonsson, Johann E., Andersen, Bogi
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Differentiation Cells, Cultured epidermal differentation Epidermis fibroblast Hand human epidermis Humans keratinocyte Keratinocytes palm palmoplantar skin RNA FISH single-cell RNA sequencing Skin sole
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