Hedgehog signaling regulates Wolffian duct development through the primary cilium

Primary cilia play pivotal roles in embryonic patterning and organogenesis through transduction of the Hedgehog signaling pathway (Hh). Although mutations in Hh morphogens impair the development of the gonads and trigger male infertility, the contribution of Hh and primary cilia in the development o...

Ausführliche Beschreibung