Indocyanine-enhanced mouse model of bleomycin-induced lung fibrosis with hallmarks of progressive emphysema

The development of new drugs for idiopathic pulmonary fibrosis strongly relies on preclinical experimentation, which requires the continuous improvement of animal models and integration with in vivo imaging data. Here, we investigated the lung distribution of bleomycin (BLM) associated with the indo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 2023-02, Vol.324 (2), p.L211-L227
Hauptverfasser:	Grandi, Andrea, Ferrini, Erica, Mecozzi, Laura, Ciccimarra, Roberta, Zoboli, Matteo, Leo, Ludovica, Khalajzeyqami, Zahra, Kleinjan, Alex, Löwik, Clemens W G M, Donofrio, Gaetano, Villetti, Gino, Stellari, Franco Fabio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bleomycin Bronchoalveolar Lavage Fluid Disease Models, Animal Emphysema - pathology Humans Idiopathic Pulmonary Fibrosis - chemically induced Idiopathic Pulmonary Fibrosis - diagnostic imaging Idiopathic Pulmonary Fibrosis - pathology Lung - diagnostic imaging Lung - pathology Mice Mice, Inbred C57BL Pulmonary Emphysema - chemically induced Pulmonary Emphysema - diagnostic imaging Pulmonary Emphysema - pathology X-Ray Microtomography
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!