Weight Loss, Lifestyle Intervention, and Metformin Affect Longitudinal Relationship of Insulin Secretion and Sensitivity

Insulin secretion and sensitivity regulate glycemia, with inadequately compensated deficiencies leading to diabetes. We investigated effects of weight loss, an intensive lifestyle intervention (ILS), and metformin on the relationship between insulin secretion and sensitivity using repository data fr...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2022-11, Vol.107 (11), p.3086-3099
Hauptverfasser:	Vazquez Arreola, Elsa, Knowler, William C, Hanson, Robert L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis Blood Glucose Clinical Development and progression Dextrose Diabetes Mellitus, Type 2 Glucose Glucose tolerance tests Humans Hypoglycemic Agents - therapeutic use Insulin Insulin - metabolism Insulin Secretion Life Style Metformin Metformin - therapeutic use Type 2 diabetes Weight Loss - physiology
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