Endothelial Cell Phenotypes Demonstrate Different Metabolic Patterns and Predict Mortality in Trauma Patients

In trauma patients, shock-induced endotheliopathy (SHINE) is associated with a poor prognosis. We have previously identified four metabolic phenotypes in a small cohort of trauma patients (N = 20) and displayed the intracellular metabolic profile of the endothelial cell by integrating quantified pla...

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Veröffentlicht in:	International journal of molecular sciences 2023-01, Vol.24 (3), p.2257
Hauptverfasser:	Henriksen, Hanne H, Marín de Mas, Igor, Nielsen, Lars K, Krocker, Joseph, Stensballe, Jakob, Karvelsson, Sigurður T, Secher, Niels H, Rolfsson, Óttar, Wade, Charles E, Johansson, Pär I
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphate Amino acids Catecholamines Computer applications Endothelial Cells Fatty acids Genomes Genotype & phenotype Glucose Homeostasis Humans Lipids Mass spectrometry Mass spectroscopy Medical prognosis Metabolism Metabolites Metabolomics Mortality Network analysis Oxidation Oxidative stress Phenotype Phenotypes Plasma Prospective Studies Shock Trauma
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