All-Cause Standardized Mortality Ratio in Hemodialysis and Peritoneal Dialysis Patients: A Nationwide Population-Based Cohort Study
Patients with end-stage renal disease (ESRD) are at a higher mortality risk compared with the general population. Previous studies have described a relationship between mortality and patients with ESRD, but the data on standardized mortality ratio (SMR) corresponding to different causes of death in...
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| Veröffentlicht in: | International journal of environmental research and public health 2023-01, Vol.20 (3), p.2347 |
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| creator | Lee, Yi-Che Lin, Chi-Wei Ho, Li-Chun Hung, Shih-Yuan Wang, Hao-Kuang Chang, Min-Yu Liou, Hung-Hsiang Wang, Hsi-Hao Chiou, Yuan-Yow Lin, Sheng-Hsiang |
| description | Patients with end-stage renal disease (ESRD) are at a higher mortality risk compared with the general population. Previous studies have described a relationship between mortality and patients with ESRD, but the data on standardized mortality ratio (SMR) corresponding to different causes of death in patients undergoing hemodialysis (HD) and peritoneal dialysis (PD) are limited. This study was designed as a nationwide population-based retrospective cohort study. Incident dialysis patients between January 2000 and December 2015 in Taiwan were included. Using data acquired from the Taiwan Death Registry, SMR values were calculated and compared with the overall survival. The results showed there were a total of 128,966 patients enrolled, including 117,376 incident HD patients and 11,590 incident PD patients. It was found that 75,297 patients (58.4%) died during the period of 2000-2017. The overall SMR was 5.21. The neoplasms SMR was 2.11; the endocrine, nutritional, metabolic, and immunity disorders SMR was 13.53; the circulatory system SMR was 4.31; the respiratory system SMR was 2.59; the digestive system SMR was 6.1; and the genitourinary system SMR was 27.22. Therefore, more attention should be paid to these diseases in clinical care. |
| doi_str_mv | 10.3390/ijerph20032347 |
| format | Article |
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Previous studies have described a relationship between mortality and patients with ESRD, but the data on standardized mortality ratio (SMR) corresponding to different causes of death in patients undergoing hemodialysis (HD) and peritoneal dialysis (PD) are limited. This study was designed as a nationwide population-based retrospective cohort study. Incident dialysis patients between January 2000 and December 2015 in Taiwan were included. Using data acquired from the Taiwan Death Registry, SMR values were calculated and compared with the overall survival. The results showed there were a total of 128,966 patients enrolled, including 117,376 incident HD patients and 11,590 incident PD patients. It was found that 75,297 patients (58.4%) died during the period of 2000-2017. The overall SMR was 5.21. The neoplasms SMR was 2.11; the endocrine, nutritional, metabolic, and immunity disorders SMR was 13.53; the circulatory system SMR was 4.31; the respiratory system SMR was 2.59; the digestive system SMR was 6.1; and the genitourinary system SMR was 27.22. Therefore, more attention should be paid to these diseases in clinical care.</description><identifier>ISSN: 1660-4601</identifier><identifier>ISSN: 1661-7827</identifier><identifier>EISSN: 1660-4601</identifier><identifier>DOI: 10.3390/ijerph20032347</identifier><identifier>PMID: 36767713</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Circulatory system ; Cohort analysis ; Cohort Studies ; Data acquisition ; Death ; Dialysis ; Digestive system ; Disease ; End-stage renal disease ; Hemodialysis ; Hospitals ; Humans ; Illnesses ; Kidney diseases ; Kidney Failure, Chronic - epidemiology ; Kidney Failure, Chronic - therapy ; Medical diagnosis ; Metabolism ; Mortality ; National health insurance ; Neoplasms ; Patients ; Peritoneal Dialysis ; Peritoneum ; Population ; Population studies ; Population-based studies ; Renal Dialysis ; Respiratory system ; Retrospective Studies ; Review boards ; Tumors ; Urogenital system ; Womens health</subject><ispartof>International journal of environmental research and public health, 2023-01, Vol.20 (3), p.2347</ispartof><rights>2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2023 by the authors. 2023</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3337-34602a3616a4781b867c9a29335e6bf163719fa8963b331c13caaeef6a00525e3</citedby><cites>FETCH-LOGICAL-c3337-34602a3616a4781b867c9a29335e6bf163719fa8963b331c13caaeef6a00525e3</cites><orcidid>0000-0003-3493-8892 ; 0000-0001-8050-0029 ; 0000-0002-2925-5352</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915131/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9915131/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36767713$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lee, Yi-Che</creatorcontrib><creatorcontrib>Lin, Chi-Wei</creatorcontrib><creatorcontrib>Ho, Li-Chun</creatorcontrib><creatorcontrib>Hung, Shih-Yuan</creatorcontrib><creatorcontrib>Wang, Hao-Kuang</creatorcontrib><creatorcontrib>Chang, Min-Yu</creatorcontrib><creatorcontrib>Liou, Hung-Hsiang</creatorcontrib><creatorcontrib>Wang, Hsi-Hao</creatorcontrib><creatorcontrib>Chiou, Yuan-Yow</creatorcontrib><creatorcontrib>Lin, Sheng-Hsiang</creatorcontrib><title>All-Cause Standardized Mortality Ratio in Hemodialysis and Peritoneal Dialysis Patients: A Nationwide Population-Based Cohort Study</title><title>International journal of environmental research and public health</title><addtitle>Int J Environ Res Public Health</addtitle><description>Patients with end-stage renal disease (ESRD) are at a higher mortality risk compared with the general population. Previous studies have described a relationship between mortality and patients with ESRD, but the data on standardized mortality ratio (SMR) corresponding to different causes of death in patients undergoing hemodialysis (HD) and peritoneal dialysis (PD) are limited. This study was designed as a nationwide population-based retrospective cohort study. Incident dialysis patients between January 2000 and December 2015 in Taiwan were included. Using data acquired from the Taiwan Death Registry, SMR values were calculated and compared with the overall survival. The results showed there were a total of 128,966 patients enrolled, including 117,376 incident HD patients and 11,590 incident PD patients. It was found that 75,297 patients (58.4%) died during the period of 2000-2017. The overall SMR was 5.21. The neoplasms SMR was 2.11; the endocrine, nutritional, metabolic, and immunity disorders SMR was 13.53; the circulatory system SMR was 4.31; the respiratory system SMR was 2.59; the digestive system SMR was 6.1; and the genitourinary system SMR was 27.22. Therefore, more attention should be paid to these diseases in clinical care.</description><subject>Circulatory system</subject><subject>Cohort analysis</subject><subject>Cohort Studies</subject><subject>Data acquisition</subject><subject>Death</subject><subject>Dialysis</subject><subject>Digestive system</subject><subject>Disease</subject><subject>End-stage renal disease</subject><subject>Hemodialysis</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Illnesses</subject><subject>Kidney diseases</subject><subject>Kidney Failure, Chronic - epidemiology</subject><subject>Kidney Failure, Chronic - therapy</subject><subject>Medical diagnosis</subject><subject>Metabolism</subject><subject>Mortality</subject><subject>National health insurance</subject><subject>Neoplasms</subject><subject>Patients</subject><subject>Peritoneal Dialysis</subject><subject>Peritoneum</subject><subject>Population</subject><subject>Population studies</subject><subject>Population-based studies</subject><subject>Renal Dialysis</subject><subject>Respiratory system</subject><subject>Retrospective Studies</subject><subject>Review boards</subject><subject>Tumors</subject><subject>Urogenital system</subject><subject>Womens health</subject><issn>1660-4601</issn><issn>1661-7827</issn><issn>1660-4601</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNpdkc2P0zAQxS0EYpfClSOyxIVLFjuT2DEHpFIWFmmBio-zNU0m1JUbFzthVa7847jsh3Y52R7_5s08PcaeSnECYMRLt6G4W5dCQAmVvseOpVKiqJSQ92_dj9ijlDYZaiplHrIjUFppLeGY_Zl7XyxwSsS_jjh0GDv3mzr-McQRvRv3_AuOLnA38DPahs6h3yeXeEb5kqIbw0Do-dvr-jLTNIzpFZ_zT4fO4cJ1xJdhN_l_z-INpqy_COs8Ic-cuv1j9qBHn-jJ1Tlj39-dflucFeef339YzM-LFgB0AdlJiaCkwko3ctUo3RosDUBNatVLBVqaHhujYAUgWwktIlGvUIi6rAlm7PWl7m5abalr854Rvd1Ft8W4twGdvfszuLX9EX5ZY2QtQWaBF1cCMfycKI1261JL3uNAYUq21LpWUtegM_r8P3QTpjhkeweqagzIvOeMnVxSbQwpRepvlpHCHvK1d_PNDc9uW7jBrwOFv_u7o2g</recordid><startdate>20230128</startdate><enddate>20230128</enddate><creator>Lee, Yi-Che</creator><creator>Lin, Chi-Wei</creator><creator>Ho, Li-Chun</creator><creator>Hung, Shih-Yuan</creator><creator>Wang, Hao-Kuang</creator><creator>Chang, Min-Yu</creator><creator>Liou, Hung-Hsiang</creator><creator>Wang, Hsi-Hao</creator><creator>Chiou, Yuan-Yow</creator><creator>Lin, Sheng-Hsiang</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-3493-8892</orcidid><orcidid>https://orcid.org/0000-0001-8050-0029</orcidid><orcidid>https://orcid.org/0000-0002-2925-5352</orcidid></search><sort><creationdate>20230128</creationdate><title>All-Cause Standardized Mortality Ratio in Hemodialysis and Peritoneal Dialysis Patients: A Nationwide Population-Based Cohort Study</title><author>Lee, Yi-Che ; 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Previous studies have described a relationship between mortality and patients with ESRD, but the data on standardized mortality ratio (SMR) corresponding to different causes of death in patients undergoing hemodialysis (HD) and peritoneal dialysis (PD) are limited. This study was designed as a nationwide population-based retrospective cohort study. Incident dialysis patients between January 2000 and December 2015 in Taiwan were included. Using data acquired from the Taiwan Death Registry, SMR values were calculated and compared with the overall survival. The results showed there were a total of 128,966 patients enrolled, including 117,376 incident HD patients and 11,590 incident PD patients. It was found that 75,297 patients (58.4%) died during the period of 2000-2017. The overall SMR was 5.21. The neoplasms SMR was 2.11; the endocrine, nutritional, metabolic, and immunity disorders SMR was 13.53; the circulatory system SMR was 4.31; the respiratory system SMR was 2.59; the digestive system SMR was 6.1; and the genitourinary system SMR was 27.22. Therefore, more attention should be paid to these diseases in clinical care.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>36767713</pmid><doi>10.3390/ijerph20032347</doi><orcidid>https://orcid.org/0000-0003-3493-8892</orcidid><orcidid>https://orcid.org/0000-0001-8050-0029</orcidid><orcidid>https://orcid.org/0000-0002-2925-5352</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Circulatory system Cohort analysis Cohort Studies Data acquisition Death Dialysis Digestive system Disease End-stage renal disease Hemodialysis Hospitals Humans Illnesses Kidney diseases Kidney Failure, Chronic - epidemiology Kidney Failure, Chronic - therapy Medical diagnosis Metabolism Mortality National health insurance Neoplasms Patients Peritoneal Dialysis Peritoneum Population Population studies Population-based studies Renal Dialysis Respiratory system Retrospective Studies Review boards Tumors Urogenital system Womens health |
| title | All-Cause Standardized Mortality Ratio in Hemodialysis and Peritoneal Dialysis Patients: A Nationwide Population-Based Cohort Study |
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