Dietary fiber supplementation during the last 50 days of gestation improves the farrowing performance of gilts by modulating insulin sensitivity, gut microbiota, and placental function
Abstract Our previous study found dietary konjac flour (KF) supplementation could improve insulin sensitivity and reproductive performance of sows, but its high price limits its application in actual production. This study aimed to investigate the effects of supplementation of a cheaper combined die...
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| creator | Huang, Shuangbo Wu, Deyuan Hao, Xiangyu Nie, Jiawei Huang, Zihao Ma, Shuo Chen, Yiling Chen, Shengxing Wu, Jianyao Sun, Jihui Ao, Huasun Gao, Binghui Tan, Chengquan |
| description | Abstract
Our previous study found dietary konjac flour (KF) supplementation could improve insulin sensitivity and reproductive performance of sows, but its high price limits its application in actual production. This study aimed to investigate the effects of supplementation of a cheaper combined dietary fiber (CDF, using bamboo shoots fiber and alginate fiber to partially replace KF) from the last 50 days of gestation to parturition on farrowing performance, insulin sensitivity, gut microbiota, and placental function of gilts. Specifically, a total of 135 pregnant gilts with a similar farrowing time were blocked by backfat thickness and body weight on day 65 of gestation (G65d) and assigned to 1 of the 3 dietary treatment groups (n = 45 per group): basal diet (CON), basal diet supplemented with 2% KF or 2% CDF (CDF containing 15% KF, 60% bamboo shoots fiber, and 25% alginate fiber), respectively. The litter performance, insulin sensitivity and glucose tolerance parameters, placental vessel density, and short-chain fatty acids (SCFAs) levels in feces were assessed. The gut microbiota population in gilts during gestation was also assessed by 16S rDNA gene sequencing. Compared with CON, both KF and CDF treatments not only increased the piglet birth weight (P < 0.05) and piglet vitality (P < 0.01) but also decreased the proportion of piglets with birth weight ≤ 1.2 kg (P < 0.01) and increased the proportion of piglets with birth weight ≥ 1.5 kg (P < 0.01). In addition, KF or CDF supplementation reduced fasting blood insulin level (P < 0.05), homeostasis model assessment-insulin resistance (P < 0.05), serum hemoglobin A1c (P < 0.05), and the level of advanced glycation end products (P < 0.05) at G110d, and increased the placental vascular density (P < 0.05) at farrowing. Meanwhile, KF or CDF supplementation increased microbial diversity (P < 0.05) and SCFAs levels (P < 0.05) in feces at G110d. Notably, the production cost per live-born piglet was lower in CDF group (¥ 36.1) than KF group (¥ 41.3). Overall, KF or CDF supplementation from G65d to farrowing could improve the farrowing performance of gilts possibly by improving insulin sensitivity, regulating gut microbiota and metabolites, and increasing placental vascular density, with higher economic benefits and a similar effect for CDF vs. KF, suggesting the potential of CDF as a cheaper alternative to KF in actual production.
This work examined the impact of 2% konjac flour (KF) and 2% combined dietary fiber |
| doi_str_mv | 10.1093/jas/skad021 |
| format | Article |
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Our previous study found dietary konjac flour (KF) supplementation could improve insulin sensitivity and reproductive performance of sows, but its high price limits its application in actual production. This study aimed to investigate the effects of supplementation of a cheaper combined dietary fiber (CDF, using bamboo shoots fiber and alginate fiber to partially replace KF) from the last 50 days of gestation to parturition on farrowing performance, insulin sensitivity, gut microbiota, and placental function of gilts. Specifically, a total of 135 pregnant gilts with a similar farrowing time were blocked by backfat thickness and body weight on day 65 of gestation (G65d) and assigned to 1 of the 3 dietary treatment groups (n = 45 per group): basal diet (CON), basal diet supplemented with 2% KF or 2% CDF (CDF containing 15% KF, 60% bamboo shoots fiber, and 25% alginate fiber), respectively. The litter performance, insulin sensitivity and glucose tolerance parameters, placental vessel density, and short-chain fatty acids (SCFAs) levels in feces were assessed. The gut microbiota population in gilts during gestation was also assessed by 16S rDNA gene sequencing. Compared with CON, both KF and CDF treatments not only increased the piglet birth weight (P < 0.05) and piglet vitality (P < 0.01) but also decreased the proportion of piglets with birth weight ≤ 1.2 kg (P < 0.01) and increased the proportion of piglets with birth weight ≥ 1.5 kg (P < 0.01). In addition, KF or CDF supplementation reduced fasting blood insulin level (P < 0.05), homeostasis model assessment-insulin resistance (P < 0.05), serum hemoglobin A1c (P < 0.05), and the level of advanced glycation end products (P < 0.05) at G110d, and increased the placental vascular density (P < 0.05) at farrowing. Meanwhile, KF or CDF supplementation increased microbial diversity (P < 0.05) and SCFAs levels (P < 0.05) in feces at G110d. Notably, the production cost per live-born piglet was lower in CDF group (¥ 36.1) than KF group (¥ 41.3). Overall, KF or CDF supplementation from G65d to farrowing could improve the farrowing performance of gilts possibly by improving insulin sensitivity, regulating gut microbiota and metabolites, and increasing placental vascular density, with higher economic benefits and a similar effect for CDF vs. KF, suggesting the potential of CDF as a cheaper alternative to KF in actual production.
This work examined the impact of 2% konjac flour (KF) and 2% combined dietary fiber (CDF, containing 15% KF, 60% bamboo shoots fiber, and 25% alginate fiber) supplementation during the last 50 days of gestation on farrowing performance, insulin sensitivity, gut microbiota, and placental function of gilts. CDF dietary supplementation was found to have higher economic benefits than and a similar effect to KF on improving the reproductive performance of sows, thus a cheaper alternative to KF in actual production.
Lay Summary
Dietary konjac flour (KF) supplementation could improve insulin sensitivity and reproductive performance of sows, but its high price limits its application in actual production. This study investigated the impact of 2% konjac flour (KF) and 2% combined dietary fiber (CDF, containing 15% KF, 60% bamboo shoots fiber, and 25% alginate fiber) supplementation from the last 50 days of gestation to farrowing on farrowing performance, placental function, insulin sensitivity, and gut microbiota of gilts. Results indicated that KF or CDF supplementation during this time could improve the farrowing performance of gilts possibly by improving insulin sensitivity and gut microbiota, and increasing placental vascular density. Meanwhile, CDF could lower the production cost per live-born piglet and have a similar effect to KF, thus a cheaper alternative to KF in actual production. This study facilitates understanding the beneficial effects of KF and non-conventional dietary fiber sources on the reproductive performance of gilts.]]></description><identifier>ISSN: 0021-8812</identifier><identifier>EISSN: 1525-3163</identifier><identifier>DOI: 10.1093/jas/skad021</identifier><identifier>PMID: 36634095</identifier><language>eng</language><publisher>US: Oxford University Press</publisher><subject>Advanced glycosylation end products ; Alginates ; Alginic acid ; Animals ; Bamboo ; Birth Weight ; Blood levels ; Blood vessels ; Body weight ; Density ; Diet ; Diet - veterinary ; Dietary Fiber ; Dietary Supplements ; Fatty Acids, Volatile ; Feces ; Female ; Gastrointestinal Microbiome ; Gene sequencing ; Gestation ; Glucose tolerance ; Hemoglobin ; Homeostasis ; Insulin ; Insulin Resistance ; Intestinal microflora ; Lactation - physiology ; Metabolites ; Microbiota ; Microorganisms ; Parameter sensitivity ; Parturition ; Placenta ; Pregnancy ; Production costs ; Reproduction ; rRNA 16S ; Sus scrofa ; Swine ; Swine Diseases ; Technology in Animal Science</subject><ispartof>Journal of animal science, 2023-01, Vol.101</ispartof><rights>The Author(s) 2023. Published by Oxford University Press on behalf of the American Society of Animal Science. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. 2023</rights><rights>The Author(s) 2023. Published by Oxford University Press on behalf of the American Society of Animal Science. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c403t-cb1b22448bff7a06f22e7d4c8cfbcf95ca66a32e35954976bd81a9bc4e75640e3</citedby><cites>FETCH-LOGICAL-c403t-cb1b22448bff7a06f22e7d4c8cfbcf95ca66a32e35954976bd81a9bc4e75640e3</cites><orcidid>0000-0001-9290-1807</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912709/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912709/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,1584,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36634095$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Huang, Shuangbo</creatorcontrib><creatorcontrib>Wu, Deyuan</creatorcontrib><creatorcontrib>Hao, Xiangyu</creatorcontrib><creatorcontrib>Nie, Jiawei</creatorcontrib><creatorcontrib>Huang, Zihao</creatorcontrib><creatorcontrib>Ma, Shuo</creatorcontrib><creatorcontrib>Chen, Yiling</creatorcontrib><creatorcontrib>Chen, Shengxing</creatorcontrib><creatorcontrib>Wu, Jianyao</creatorcontrib><creatorcontrib>Sun, Jihui</creatorcontrib><creatorcontrib>Ao, Huasun</creatorcontrib><creatorcontrib>Gao, Binghui</creatorcontrib><creatorcontrib>Tan, Chengquan</creatorcontrib><title>Dietary fiber supplementation during the last 50 days of gestation improves the farrowing performance of gilts by modulating insulin sensitivity, gut microbiota, and placental function</title><title>Journal of animal science</title><addtitle>J Anim Sci</addtitle><description><![CDATA[Abstract
Our previous study found dietary konjac flour (KF) supplementation could improve insulin sensitivity and reproductive performance of sows, but its high price limits its application in actual production. This study aimed to investigate the effects of supplementation of a cheaper combined dietary fiber (CDF, using bamboo shoots fiber and alginate fiber to partially replace KF) from the last 50 days of gestation to parturition on farrowing performance, insulin sensitivity, gut microbiota, and placental function of gilts. Specifically, a total of 135 pregnant gilts with a similar farrowing time were blocked by backfat thickness and body weight on day 65 of gestation (G65d) and assigned to 1 of the 3 dietary treatment groups (n = 45 per group): basal diet (CON), basal diet supplemented with 2% KF or 2% CDF (CDF containing 15% KF, 60% bamboo shoots fiber, and 25% alginate fiber), respectively. The litter performance, insulin sensitivity and glucose tolerance parameters, placental vessel density, and short-chain fatty acids (SCFAs) levels in feces were assessed. The gut microbiota population in gilts during gestation was also assessed by 16S rDNA gene sequencing. Compared with CON, both KF and CDF treatments not only increased the piglet birth weight (P < 0.05) and piglet vitality (P < 0.01) but also decreased the proportion of piglets with birth weight ≤ 1.2 kg (P < 0.01) and increased the proportion of piglets with birth weight ≥ 1.5 kg (P < 0.01). In addition, KF or CDF supplementation reduced fasting blood insulin level (P < 0.05), homeostasis model assessment-insulin resistance (P < 0.05), serum hemoglobin A1c (P < 0.05), and the level of advanced glycation end products (P < 0.05) at G110d, and increased the placental vascular density (P < 0.05) at farrowing. Meanwhile, KF or CDF supplementation increased microbial diversity (P < 0.05) and SCFAs levels (P < 0.05) in feces at G110d. Notably, the production cost per live-born piglet was lower in CDF group (¥ 36.1) than KF group (¥ 41.3). Overall, KF or CDF supplementation from G65d to farrowing could improve the farrowing performance of gilts possibly by improving insulin sensitivity, regulating gut microbiota and metabolites, and increasing placental vascular density, with higher economic benefits and a similar effect for CDF vs. KF, suggesting the potential of CDF as a cheaper alternative to KF in actual production.
This work examined the impact of 2% konjac flour (KF) and 2% combined dietary fiber (CDF, containing 15% KF, 60% bamboo shoots fiber, and 25% alginate fiber) supplementation during the last 50 days of gestation on farrowing performance, insulin sensitivity, gut microbiota, and placental function of gilts. CDF dietary supplementation was found to have higher economic benefits than and a similar effect to KF on improving the reproductive performance of sows, thus a cheaper alternative to KF in actual production.
Lay Summary
Dietary konjac flour (KF) supplementation could improve insulin sensitivity and reproductive performance of sows, but its high price limits its application in actual production. This study investigated the impact of 2% konjac flour (KF) and 2% combined dietary fiber (CDF, containing 15% KF, 60% bamboo shoots fiber, and 25% alginate fiber) supplementation from the last 50 days of gestation to farrowing on farrowing performance, placental function, insulin sensitivity, and gut microbiota of gilts. Results indicated that KF or CDF supplementation during this time could improve the farrowing performance of gilts possibly by improving insulin sensitivity and gut microbiota, and increasing placental vascular density. Meanwhile, CDF could lower the production cost per live-born piglet and have a similar effect to KF, thus a cheaper alternative to KF in actual production. This study facilitates understanding the beneficial effects of KF and non-conventional dietary fiber sources on the reproductive performance of gilts.]]></description><subject>Advanced glycosylation end products</subject><subject>Alginates</subject><subject>Alginic acid</subject><subject>Animals</subject><subject>Bamboo</subject><subject>Birth Weight</subject><subject>Blood levels</subject><subject>Blood vessels</subject><subject>Body weight</subject><subject>Density</subject><subject>Diet</subject><subject>Diet - veterinary</subject><subject>Dietary Fiber</subject><subject>Dietary Supplements</subject><subject>Fatty Acids, Volatile</subject><subject>Feces</subject><subject>Female</subject><subject>Gastrointestinal Microbiome</subject><subject>Gene sequencing</subject><subject>Gestation</subject><subject>Glucose tolerance</subject><subject>Hemoglobin</subject><subject>Homeostasis</subject><subject>Insulin</subject><subject>Insulin Resistance</subject><subject>Intestinal microflora</subject><subject>Lactation - physiology</subject><subject>Metabolites</subject><subject>Microbiota</subject><subject>Microorganisms</subject><subject>Parameter sensitivity</subject><subject>Parturition</subject><subject>Placenta</subject><subject>Pregnancy</subject><subject>Production costs</subject><subject>Reproduction</subject><subject>rRNA 16S</subject><subject>Sus scrofa</subject><subject>Swine</subject><subject>Swine Diseases</subject><subject>Technology in Animal Science</subject><issn>0021-8812</issn><issn>1525-3163</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9ksuKFDEYhYMoTtu6ci8BQQSnnFwqVV2bARmvMOBG1yFJJT1pU0mZS0u_mY9narod1IWrQPL9JycnB4CnGL3GaKAXO5Eu0jcxIoLvgRVmhDUUd_Q-WKG61Ww2mJyBRyntEMKEDewhOKNdR1s0sBX4-dbqLOIBGit1hKnMs9OT9llkGzwcS7R-C_ONhk6kDBmCozgkGAzc6nSC7DTHsNfpFjMixvBjGZp1NCFOwit9y1uXE5QHOIWxuDpZEetTcdbDpH2y2e5tPpzDbclwsioGaUMW51D4Ec5OqMWUg6Z4tdz6GDwwwiX95LSuwdf3775cfWyuP3_4dPXmulEtorlREktC2nYjjekF6gwhuh9btVFGKjMwJbpOUKJpDaYd-k6OGywGqVrds65Fmq7B5VF3LnLS4-IiCsfnaKcaGw_C8r9PvL3h27Dnw4BJX_9nDV6eBGL4XmpofLJJaeeE16EkTvqOoR6hancNnv-D7kKJvj6PU9RiVB2yvlKvjlSNKKWozZ0ZjPjSCF4bwU-NqPSzP_3fsb8rUIEXRyCU-b9KvwBzVcYq</recordid><startdate>20230103</startdate><enddate>20230103</enddate><creator>Huang, Shuangbo</creator><creator>Wu, Deyuan</creator><creator>Hao, Xiangyu</creator><creator>Nie, Jiawei</creator><creator>Huang, Zihao</creator><creator>Ma, Shuo</creator><creator>Chen, Yiling</creator><creator>Chen, Shengxing</creator><creator>Wu, Jianyao</creator><creator>Sun, Jihui</creator><creator>Ao, Huasun</creator><creator>Gao, Binghui</creator><creator>Tan, Chengquan</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>U9A</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-9290-1807</orcidid></search><sort><creationdate>20230103</creationdate><title>Dietary fiber supplementation during the last 50 days of gestation improves the farrowing performance of gilts by modulating insulin sensitivity, gut microbiota, and placental function</title><author>Huang, Shuangbo ; Wu, Deyuan ; Hao, Xiangyu ; Nie, Jiawei ; Huang, Zihao ; Ma, Shuo ; Chen, Yiling ; Chen, Shengxing ; Wu, Jianyao ; Sun, Jihui ; Ao, Huasun ; Gao, Binghui ; Tan, Chengquan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c403t-cb1b22448bff7a06f22e7d4c8cfbcf95ca66a32e35954976bd81a9bc4e75640e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Advanced glycosylation end products</topic><topic>Alginates</topic><topic>Alginic acid</topic><topic>Animals</topic><topic>Bamboo</topic><topic>Birth Weight</topic><topic>Blood levels</topic><topic>Blood vessels</topic><topic>Body weight</topic><topic>Density</topic><topic>Diet</topic><topic>Diet - veterinary</topic><topic>Dietary Fiber</topic><topic>Dietary Supplements</topic><topic>Fatty Acids, Volatile</topic><topic>Feces</topic><topic>Female</topic><topic>Gastrointestinal Microbiome</topic><topic>Gene sequencing</topic><topic>Gestation</topic><topic>Glucose tolerance</topic><topic>Hemoglobin</topic><topic>Homeostasis</topic><topic>Insulin</topic><topic>Insulin Resistance</topic><topic>Intestinal microflora</topic><topic>Lactation - physiology</topic><topic>Metabolites</topic><topic>Microbiota</topic><topic>Microorganisms</topic><topic>Parameter sensitivity</topic><topic>Parturition</topic><topic>Placenta</topic><topic>Pregnancy</topic><topic>Production costs</topic><topic>Reproduction</topic><topic>rRNA 16S</topic><topic>Sus scrofa</topic><topic>Swine</topic><topic>Swine Diseases</topic><topic>Technology in Animal Science</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Huang, Shuangbo</creatorcontrib><creatorcontrib>Wu, Deyuan</creatorcontrib><creatorcontrib>Hao, Xiangyu</creatorcontrib><creatorcontrib>Nie, Jiawei</creatorcontrib><creatorcontrib>Huang, Zihao</creatorcontrib><creatorcontrib>Ma, Shuo</creatorcontrib><creatorcontrib>Chen, Yiling</creatorcontrib><creatorcontrib>Chen, Shengxing</creatorcontrib><creatorcontrib>Wu, Jianyao</creatorcontrib><creatorcontrib>Sun, Jihui</creatorcontrib><creatorcontrib>Ao, Huasun</creatorcontrib><creatorcontrib>Gao, Binghui</creatorcontrib><creatorcontrib>Tan, Chengquan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of animal science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Huang, Shuangbo</au><au>Wu, Deyuan</au><au>Hao, Xiangyu</au><au>Nie, Jiawei</au><au>Huang, Zihao</au><au>Ma, Shuo</au><au>Chen, Yiling</au><au>Chen, Shengxing</au><au>Wu, Jianyao</au><au>Sun, Jihui</au><au>Ao, Huasun</au><au>Gao, Binghui</au><au>Tan, Chengquan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dietary fiber supplementation during the last 50 days of gestation improves the farrowing performance of gilts by modulating insulin sensitivity, gut microbiota, and placental function</atitle><jtitle>Journal of animal science</jtitle><addtitle>J Anim Sci</addtitle><date>2023-01-03</date><risdate>2023</risdate><volume>101</volume><issn>0021-8812</issn><eissn>1525-3163</eissn><abstract><![CDATA[Abstract
Our previous study found dietary konjac flour (KF) supplementation could improve insulin sensitivity and reproductive performance of sows, but its high price limits its application in actual production. This study aimed to investigate the effects of supplementation of a cheaper combined dietary fiber (CDF, using bamboo shoots fiber and alginate fiber to partially replace KF) from the last 50 days of gestation to parturition on farrowing performance, insulin sensitivity, gut microbiota, and placental function of gilts. Specifically, a total of 135 pregnant gilts with a similar farrowing time were blocked by backfat thickness and body weight on day 65 of gestation (G65d) and assigned to 1 of the 3 dietary treatment groups (n = 45 per group): basal diet (CON), basal diet supplemented with 2% KF or 2% CDF (CDF containing 15% KF, 60% bamboo shoots fiber, and 25% alginate fiber), respectively. The litter performance, insulin sensitivity and glucose tolerance parameters, placental vessel density, and short-chain fatty acids (SCFAs) levels in feces were assessed. The gut microbiota population in gilts during gestation was also assessed by 16S rDNA gene sequencing. Compared with CON, both KF and CDF treatments not only increased the piglet birth weight (P < 0.05) and piglet vitality (P < 0.01) but also decreased the proportion of piglets with birth weight ≤ 1.2 kg (P < 0.01) and increased the proportion of piglets with birth weight ≥ 1.5 kg (P < 0.01). In addition, KF or CDF supplementation reduced fasting blood insulin level (P < 0.05), homeostasis model assessment-insulin resistance (P < 0.05), serum hemoglobin A1c (P < 0.05), and the level of advanced glycation end products (P < 0.05) at G110d, and increased the placental vascular density (P < 0.05) at farrowing. Meanwhile, KF or CDF supplementation increased microbial diversity (P < 0.05) and SCFAs levels (P < 0.05) in feces at G110d. Notably, the production cost per live-born piglet was lower in CDF group (¥ 36.1) than KF group (¥ 41.3). Overall, KF or CDF supplementation from G65d to farrowing could improve the farrowing performance of gilts possibly by improving insulin sensitivity, regulating gut microbiota and metabolites, and increasing placental vascular density, with higher economic benefits and a similar effect for CDF vs. KF, suggesting the potential of CDF as a cheaper alternative to KF in actual production.
This work examined the impact of 2% konjac flour (KF) and 2% combined dietary fiber (CDF, containing 15% KF, 60% bamboo shoots fiber, and 25% alginate fiber) supplementation during the last 50 days of gestation on farrowing performance, insulin sensitivity, gut microbiota, and placental function of gilts. CDF dietary supplementation was found to have higher economic benefits than and a similar effect to KF on improving the reproductive performance of sows, thus a cheaper alternative to KF in actual production.
Lay Summary
Dietary konjac flour (KF) supplementation could improve insulin sensitivity and reproductive performance of sows, but its high price limits its application in actual production. This study investigated the impact of 2% konjac flour (KF) and 2% combined dietary fiber (CDF, containing 15% KF, 60% bamboo shoots fiber, and 25% alginate fiber) supplementation from the last 50 days of gestation to farrowing on farrowing performance, placental function, insulin sensitivity, and gut microbiota of gilts. Results indicated that KF or CDF supplementation during this time could improve the farrowing performance of gilts possibly by improving insulin sensitivity and gut microbiota, and increasing placental vascular density. Meanwhile, CDF could lower the production cost per live-born piglet and have a similar effect to KF, thus a cheaper alternative to KF in actual production. This study facilitates understanding the beneficial effects of KF and non-conventional dietary fiber sources on the reproductive performance of gilts.]]></abstract><cop>US</cop><pub>Oxford University Press</pub><pmid>36634095</pmid><doi>10.1093/jas/skad021</doi><orcidid>https://orcid.org/0000-0001-9290-1807</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of animal science, 2023-01, Vol.101 |
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| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9912709 |
| source | MEDLINE; Oxford University Press Journals All Titles (1996-Current); EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Advanced glycosylation end products Alginates Alginic acid Animals Bamboo Birth Weight Blood levels Blood vessels Body weight Density Diet Diet - veterinary Dietary Fiber Dietary Supplements Fatty Acids, Volatile Feces Female Gastrointestinal Microbiome Gene sequencing Gestation Glucose tolerance Hemoglobin Homeostasis Insulin Insulin Resistance Intestinal microflora Lactation - physiology Metabolites Microbiota Microorganisms Parameter sensitivity Parturition Placenta Pregnancy Production costs Reproduction rRNA 16S Sus scrofa Swine Swine Diseases Technology in Animal Science |
| title | Dietary fiber supplementation during the last 50 days of gestation improves the farrowing performance of gilts by modulating insulin sensitivity, gut microbiota, and placental function |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T03%3A48%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Dietary%20fiber%20supplementation%20during%20the%20last%2050%20days%20of%20gestation%20improves%20the%20farrowing%20performance%20of%20gilts%20by%20modulating%20insulin%20sensitivity,%20gut%20microbiota,%20and%20placental%20function&rft.jtitle=Journal%20of%20animal%20science&rft.au=Huang,%20Shuangbo&rft.date=2023-01-03&rft.volume=101&rft.issn=0021-8812&rft.eissn=1525-3163&rft_id=info:doi/10.1093/jas/skad021&rft_dat=%3Cproquest_pubme%3E3041054957%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=3041054957&rft_id=info:pmid/36634095&rft_oup_id=10.1093/jas/skad021&rfr_iscdi=true |