MYC: a complex problem

The MYC protooncogene functions as a universal amplifier of transcription through interaction with numerous factors and complexes that regulate almost every cellular process. However, a comprehensive model that explains MYC’s actions and the interplay governing the complicated dynamics of components...

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Veröffentlicht in:	Trends in cell biology 2023-03, Vol.33 (3), p.235-246
Hauptverfasser:	Das, Subhendu K., Lewis, Brian A., Levens, David
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA topology Gene Expression Regulation Humans intrinsically disordered proteins multistep reactions MYC MYC–topoisome complex protein complexes Proto-Oncogene Proteins c-myc - genetics Proto-Oncogene Proteins c-myc - metabolism RNA polymerase topoisomerase transcription cycle
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