An Increased Diagnostic Accuracy of Significant Coronary Artery Stenosis Using 320-slice Computed Tomography with Model-based Iterative Reconstruction in Cases with Severely Calcified Coronary Arteries

Objective High-quality images can be obtained with 320-slice computed tomography (CT) with model-based iterative reconstruction (MBIR). We therefore investigated the diagnostic accuracy of 320-slice CT with MBIR for detecting significant coronary artery stenosis. Methods This was a retrospective stu...

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Veröffentlicht in:Internal Medicine 2023/01/15, Vol.62(2), pp.169-176
Hauptverfasser: Takahashi, Manami, Takaoka, Hiroyuki, Ota, Joji, Yashima, Satomi, Kinoshita, Makiko, Suzuki-Eguchi, Noriko, Sasaki, Haruka, Goto, Hiroki, Aoki, Shuhei, Kitahara, Hideki, Sano, Koichi, Kobayashi, Yoshio
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container_end_page 176
container_issue 2
container_start_page 169
container_title Internal Medicine
container_volume 62
creator Takahashi, Manami
Takaoka, Hiroyuki
Ota, Joji
Yashima, Satomi
Kinoshita, Makiko
Suzuki-Eguchi, Noriko
Sasaki, Haruka
Goto, Hiroki
Aoki, Shuhei
Kitahara, Hideki
Sano, Koichi
Kobayashi, Yoshio
description Objective High-quality images can be obtained with 320-slice computed tomography (CT) with model-based iterative reconstruction (MBIR). We therefore investigated the diagnostic accuracy of 320-slice CT with MBIR for detecting significant coronary artery stenosis. Methods This was a retrospective study of 160 patients who underwent coronary CT and invasive coronary angiography (ICA). The first 100 consecutive patients (Group 1) underwent 320-slice CT without MBIR or small-focus scanning. The next 60 consecutive patients (Group 2) underwent 320-slice CT with both MBIR and small-focus scanning. Patients who underwent coronary artery bypass surgery were excluded. The diagnostic performance of 320-slice CT without MBIR or small-focus scanning and 320-slice CT with both of them, with ICA regarded as a reference standard, was compared to detect significant coronary artery stenosis (≥70% on CT, ≥75% on ICA). Results In a patient-based analysis, the sensitivity, specificity, and overall accuracy of detection of significant stenosis on CT against ICA were 95%, 85%, and 91% in Group 1, and 93%, 83%, and 90% in Group 2, respectively. No significant differences were observed between the two groups in the patient- and segment-based analyses. However, among cases with a severe coronary artery calcium score >400 (31 cases in Group 1 and 28 in Group 2), the specificity and overall accuracy were significantly higher (all p
doi_str_mv 10.2169/internalmedicine.9509-22
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We therefore investigated the diagnostic accuracy of 320-slice CT with MBIR for detecting significant coronary artery stenosis. Methods This was a retrospective study of 160 patients who underwent coronary CT and invasive coronary angiography (ICA). The first 100 consecutive patients (Group 1) underwent 320-slice CT without MBIR or small-focus scanning. The next 60 consecutive patients (Group 2) underwent 320-slice CT with both MBIR and small-focus scanning. Patients who underwent coronary artery bypass surgery were excluded. The diagnostic performance of 320-slice CT without MBIR or small-focus scanning and 320-slice CT with both of them, with ICA regarded as a reference standard, was compared to detect significant coronary artery stenosis (≥70% on CT, ≥75% on ICA). Results In a patient-based analysis, the sensitivity, specificity, and overall accuracy of detection of significant stenosis on CT against ICA were 95%, 85%, and 91% in Group 1, and 93%, 83%, and 90% in Group 2, respectively. No significant differences were observed between the two groups in the patient- and segment-based analyses. However, among cases with a severe coronary artery calcium score &gt;400 (31 cases in Group 1 and 28 in Group 2), the specificity and overall accuracy were significantly higher (all p&lt;0.01) in Group 2 than in Group 1 according to the segment-based analysis. Conclusion The diagnostic accuracy of the detection of coronary artery stenosis on CT was improved using 320-slice CT with MBIR.</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.9509-22</identifier><identifier>PMID: 35676040</identifier><language>eng</language><publisher>Japan: The Japanese Society of Internal Medicine</publisher><subject>Accuracy ; Angiography ; Arteriosclerosis ; Calcification (ectopic) ; Computed tomography ; coronary angiography ; Coronary Angiography - methods ; Coronary artery ; Coronary Artery Bypass ; coronary artery disease ; Coronary Stenosis - diagnostic imaging ; Coronary vessels ; Coronary Vessels - diagnostic imaging ; Heart surgery ; Humans ; Internal medicine ; Original ; Patients ; Retrospective Studies ; Scanning ; Sensitivity and Specificity ; Stenosis ; Stents ; Tomography ; Tomography, X-Ray Computed - methods</subject><ispartof>Internal Medicine, 2023/01/15, Vol.62(2), pp.169-176</ispartof><rights>2023 by The Japanese Society of Internal Medicine</rights><rights>Copyright Japan Science and Technology Agency 2023</rights><rights>Copyright © 2023 by The Japanese Society of Internal Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c609t-7244f2091f27f137c0c8bb424c6f0a69dbfa3bd099b2aa1a4d600f74b2025f053</citedby><cites>FETCH-LOGICAL-c609t-7244f2091f27f137c0c8bb424c6f0a69dbfa3bd099b2aa1a4d600f74b2025f053</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908388/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908388/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,1877,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35676040$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Takahashi, Manami</creatorcontrib><creatorcontrib>Takaoka, Hiroyuki</creatorcontrib><creatorcontrib>Ota, Joji</creatorcontrib><creatorcontrib>Yashima, Satomi</creatorcontrib><creatorcontrib>Kinoshita, Makiko</creatorcontrib><creatorcontrib>Suzuki-Eguchi, Noriko</creatorcontrib><creatorcontrib>Sasaki, Haruka</creatorcontrib><creatorcontrib>Goto, Hiroki</creatorcontrib><creatorcontrib>Aoki, Shuhei</creatorcontrib><creatorcontrib>Kitahara, Hideki</creatorcontrib><creatorcontrib>Sano, Koichi</creatorcontrib><creatorcontrib>Kobayashi, Yoshio</creatorcontrib><title>An Increased Diagnostic Accuracy of Significant Coronary Artery Stenosis Using 320-slice Computed Tomography with Model-based Iterative Reconstruction in Cases with Severely Calcified Coronary Arteries</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>Objective High-quality images can be obtained with 320-slice computed tomography (CT) with model-based iterative reconstruction (MBIR). We therefore investigated the diagnostic accuracy of 320-slice CT with MBIR for detecting significant coronary artery stenosis. Methods This was a retrospective study of 160 patients who underwent coronary CT and invasive coronary angiography (ICA). The first 100 consecutive patients (Group 1) underwent 320-slice CT without MBIR or small-focus scanning. The next 60 consecutive patients (Group 2) underwent 320-slice CT with both MBIR and small-focus scanning. Patients who underwent coronary artery bypass surgery were excluded. The diagnostic performance of 320-slice CT without MBIR or small-focus scanning and 320-slice CT with both of them, with ICA regarded as a reference standard, was compared to detect significant coronary artery stenosis (≥70% on CT, ≥75% on ICA). Results In a patient-based analysis, the sensitivity, specificity, and overall accuracy of detection of significant stenosis on CT against ICA were 95%, 85%, and 91% in Group 1, and 93%, 83%, and 90% in Group 2, respectively. No significant differences were observed between the two groups in the patient- and segment-based analyses. However, among cases with a severe coronary artery calcium score &gt;400 (31 cases in Group 1 and 28 in Group 2), the specificity and overall accuracy were significantly higher (all p&lt;0.01) in Group 2 than in Group 1 according to the segment-based analysis. Conclusion The diagnostic accuracy of the detection of coronary artery stenosis on CT was improved using 320-slice CT with MBIR.</description><subject>Accuracy</subject><subject>Angiography</subject><subject>Arteriosclerosis</subject><subject>Calcification (ectopic)</subject><subject>Computed tomography</subject><subject>coronary angiography</subject><subject>Coronary Angiography - methods</subject><subject>Coronary artery</subject><subject>Coronary Artery Bypass</subject><subject>coronary artery disease</subject><subject>Coronary Stenosis - diagnostic imaging</subject><subject>Coronary vessels</subject><subject>Coronary Vessels - diagnostic imaging</subject><subject>Heart surgery</subject><subject>Humans</subject><subject>Internal medicine</subject><subject>Original</subject><subject>Patients</subject><subject>Retrospective Studies</subject><subject>Scanning</subject><subject>Sensitivity and Specificity</subject><subject>Stenosis</subject><subject>Stents</subject><subject>Tomography</subject><subject>Tomography, X-Ray Computed - methods</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplks2O0zAUhSMEYoaBV0CW2LDJ4NiOE2-Qqg4_lQaQ6Mzacpzr1FVqF9sp6iPyVri0VMywcaT4O-ee3JyiQBW-JhUX76xLEJwaN9BbbR1cixqLkpAnxWVFmSgbQuunxSUWVVuSfFwUL2JcY0zbRpDnxQWtecMxw5fFr5lDC6cDqAg9urFqcD4mq9FM6ykovUfeoKUdnDVWK5fQ3AfvVNijWcgZ9miZICtsRPfRugFRgss4Wg0Z3GynlE3v_MYPQW1Xe_TTphX64nsYy-7PwEX2UMnuAH0H7V1MYdLJeoesQ_NMxKNkCTsIMO7zu1HnJFn5MIeF-LJ4ZtQY4dXpeVXcf_xwN_9c3n77tJjPbkvNsUh5NYwZkjdjSGMq2mis265jhGlusOKi74yiXY-F6IhSlWI9x9g0rCOY1AbX9Kp4f_TdTl3evwaXghrlNthNjiO9svLhjbMrOfidFAK3tG2zwduTQfA_JohJbmzUMI7KgZ-iJLxhTc1Fc5j15hG69tPhx2eqaThlTDCeqfZI6eBjDGDOYSosD32Rj_siD32RhGTp638_5iz8W5AMfD0C65jUAGdAhVySEf535kSSw3GacAb1SgUJjv4GDSHj4Q</recordid><startdate>20230115</startdate><enddate>20230115</enddate><creator>Takahashi, Manami</creator><creator>Takaoka, Hiroyuki</creator><creator>Ota, Joji</creator><creator>Yashima, Satomi</creator><creator>Kinoshita, Makiko</creator><creator>Suzuki-Eguchi, Noriko</creator><creator>Sasaki, Haruka</creator><creator>Goto, Hiroki</creator><creator>Aoki, Shuhei</creator><creator>Kitahara, Hideki</creator><creator>Sano, Koichi</creator><creator>Kobayashi, Yoshio</creator><general>The Japanese Society of Internal Medicine</general><general>Japan Science and Technology Agency</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20230115</creationdate><title>An Increased Diagnostic Accuracy of Significant Coronary Artery Stenosis Using 320-slice Computed Tomography with Model-based Iterative Reconstruction in Cases with Severely Calcified Coronary Arteries</title><author>Takahashi, Manami ; Takaoka, Hiroyuki ; Ota, Joji ; Yashima, Satomi ; Kinoshita, Makiko ; Suzuki-Eguchi, Noriko ; Sasaki, Haruka ; Goto, Hiroki ; Aoki, Shuhei ; Kitahara, Hideki ; Sano, Koichi ; Kobayashi, Yoshio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c609t-7244f2091f27f137c0c8bb424c6f0a69dbfa3bd099b2aa1a4d600f74b2025f053</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Accuracy</topic><topic>Angiography</topic><topic>Arteriosclerosis</topic><topic>Calcification (ectopic)</topic><topic>Computed tomography</topic><topic>coronary angiography</topic><topic>Coronary Angiography - methods</topic><topic>Coronary artery</topic><topic>Coronary Artery Bypass</topic><topic>coronary artery disease</topic><topic>Coronary Stenosis - diagnostic imaging</topic><topic>Coronary vessels</topic><topic>Coronary Vessels - diagnostic imaging</topic><topic>Heart surgery</topic><topic>Humans</topic><topic>Internal medicine</topic><topic>Original</topic><topic>Patients</topic><topic>Retrospective Studies</topic><topic>Scanning</topic><topic>Sensitivity and Specificity</topic><topic>Stenosis</topic><topic>Stents</topic><topic>Tomography</topic><topic>Tomography, X-Ray Computed - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Takahashi, Manami</creatorcontrib><creatorcontrib>Takaoka, Hiroyuki</creatorcontrib><creatorcontrib>Ota, Joji</creatorcontrib><creatorcontrib>Yashima, Satomi</creatorcontrib><creatorcontrib>Kinoshita, Makiko</creatorcontrib><creatorcontrib>Suzuki-Eguchi, Noriko</creatorcontrib><creatorcontrib>Sasaki, Haruka</creatorcontrib><creatorcontrib>Goto, Hiroki</creatorcontrib><creatorcontrib>Aoki, Shuhei</creatorcontrib><creatorcontrib>Kitahara, Hideki</creatorcontrib><creatorcontrib>Sano, Koichi</creatorcontrib><creatorcontrib>Kobayashi, Yoshio</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Takahashi, Manami</au><au>Takaoka, Hiroyuki</au><au>Ota, Joji</au><au>Yashima, Satomi</au><au>Kinoshita, Makiko</au><au>Suzuki-Eguchi, Noriko</au><au>Sasaki, Haruka</au><au>Goto, Hiroki</au><au>Aoki, Shuhei</au><au>Kitahara, Hideki</au><au>Sano, Koichi</au><au>Kobayashi, Yoshio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An Increased Diagnostic Accuracy of Significant Coronary Artery Stenosis Using 320-slice Computed Tomography with Model-based Iterative Reconstruction in Cases with Severely Calcified Coronary Arteries</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>2023-01-15</date><risdate>2023</risdate><volume>62</volume><issue>2</issue><spage>169</spage><epage>176</epage><pages>169-176</pages><artnum>9509-22</artnum><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>Objective High-quality images can be obtained with 320-slice computed tomography (CT) with model-based iterative reconstruction (MBIR). We therefore investigated the diagnostic accuracy of 320-slice CT with MBIR for detecting significant coronary artery stenosis. Methods This was a retrospective study of 160 patients who underwent coronary CT and invasive coronary angiography (ICA). The first 100 consecutive patients (Group 1) underwent 320-slice CT without MBIR or small-focus scanning. The next 60 consecutive patients (Group 2) underwent 320-slice CT with both MBIR and small-focus scanning. Patients who underwent coronary artery bypass surgery were excluded. The diagnostic performance of 320-slice CT without MBIR or small-focus scanning and 320-slice CT with both of them, with ICA regarded as a reference standard, was compared to detect significant coronary artery stenosis (≥70% on CT, ≥75% on ICA). Results In a patient-based analysis, the sensitivity, specificity, and overall accuracy of detection of significant stenosis on CT against ICA were 95%, 85%, and 91% in Group 1, and 93%, 83%, and 90% in Group 2, respectively. No significant differences were observed between the two groups in the patient- and segment-based analyses. However, among cases with a severe coronary artery calcium score &gt;400 (31 cases in Group 1 and 28 in Group 2), the specificity and overall accuracy were significantly higher (all p&lt;0.01) in Group 2 than in Group 1 according to the segment-based analysis. Conclusion The diagnostic accuracy of the detection of coronary artery stenosis on CT was improved using 320-slice CT with MBIR.</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>35676040</pmid><doi>10.2169/internalmedicine.9509-22</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record>
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source MEDLINE; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese; PubMed Central; PubMed Central Open Access
subjects Accuracy
Angiography
Arteriosclerosis
Calcification (ectopic)
Computed tomography
coronary angiography
Coronary Angiography - methods
Coronary artery
Coronary Artery Bypass
coronary artery disease
Coronary Stenosis - diagnostic imaging
Coronary vessels
Coronary Vessels - diagnostic imaging
Heart surgery
Humans
Internal medicine
Original
Patients
Retrospective Studies
Scanning
Sensitivity and Specificity
Stenosis
Stents
Tomography
Tomography, X-Ray Computed - methods
title An Increased Diagnostic Accuracy of Significant Coronary Artery Stenosis Using 320-slice Computed Tomography with Model-based Iterative Reconstruction in Cases with Severely Calcified Coronary Arteries
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