The Cynosure of CtBP: Evolution of a Bilaterian Transcriptional Corepressor

Evolution of sequence-specific transcription factors clearly drives lineage-specific innovations, but less is known about how changes in the central transcriptional machinery may contribute to evolutionary transformations. In particular, transcriptional regulators are rich in intrinsically disordere...

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Veröffentlicht in:	Molecular biology and evolution 2023-02, Vol.40 (2)
Hauptverfasser:	Raicu, Ana-Maria, Kadiyala, Dhruva, Niblock, Madeline, Jain, Aanchal, Yang, Yahui, Bird, Kalynn M, Bertholf, Kayla, Seenivasan, Akshay, Siddiq, Mohammad, Arnosti, David N
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Oxidoreductases - genetics Alcohol Oxidoreductases - metabolism Alternative Splicing Animals Chromatin Co-Repressor Proteins - genetics Co-Repressor Proteins - metabolism Discoveries DNA binding proteins Drosophila - metabolism Genetic aspects Genetic transcription Mammals - metabolism Medical research Medicine, Experimental Oxidoreductases Phosphoproteins - genetics Phylogeny Protein Binding Repressor Proteins - chemistry Repressor Proteins - genetics RNA Transcription Factors - metabolism Vertebrates - metabolism
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