Dysregulation of CD177+ neutrophils on intraepithelial lymphocytes exacerbates gut inflammation via decreasing microbiota-derived DMF

Neutrophils synergize with intestinal resident intraepithelial lymphocytes (IELs) to serve as the first-line defense and maintain intestinal homeostasis. However, the underlying mechanisms whereby neutrophils regulate IELs to inhibit intestinal inflammation are still not completely understood. Here,...

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Veröffentlicht in:	Gut microbes 2023-12, Vol.15 (1), p.2172668
Hauptverfasser:	Chen, Huimin, Wu, Xiaohan, Sun, Ruicong, Lu, Huiying, Lin, Ritian, Gao, Xiang, Li, Gengfeng, Feng, Zhongsheng, Zhu, Ruixin, Yao, Yao, Feng, Baisui, Liu, Zhanju
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CD177 Dimethyl Fumarate Dysbiosis Gastrointestinal Microbiome Inflammation intestinal inflammation Intestinal Mucosa Intraepithelial Lymphocytes Mice Mice, Inbred C57BL Mice, Knockout Neutrophils Research Paper
Online-Zugang:	Volltext
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