Challenging the Hemodynamic Hypothesis in Heart Failure With Preserved Ejection Fraction: Is Exercise Capacity Limited by Elevated Pulmonary Capillary Wedge Pressure?

Exercise intolerance is a defining characteristic of heart failure with preserved ejection fraction (HFpEF). A marked rise in pulmonary capillary wedge pressure (PCWP) during exertion is pathognomonic for HFpEF and is thought to be a key cause of exercise intolerance. If true, acutely lowering PCWP...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2023-01, Vol.147 (5), p.378-387
Hauptverfasser:	Sarma, Satyam, MacNamara, James P., Balmain, Bryce N., Hearon, Christopher M., Wakeham, Denis J., Tomlinson, Andrew R., Hynan, Linda S., Babb, Tony G., Levine, Benjamin D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cross-Over Studies Exercise Test Exercise Tolerance Female Heart Failure - drug therapy Hemodynamics Humans Male Nitroglycerin Oxygen Pulmonary Wedge Pressure Single-Blind Method Stroke Volume
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!