Interplay of Near-Zero-Field Dephasing, Rephasing, and Relaxation Dynamics and [1-13C]Pyruvate Polarization Transfer Efficiency in Pulsed SABRE-SHEATH

Hyperpolarized [1-13C]­pyruvate is a revolutionary molecular probe enabling ultrafast metabolic MRI scans in 1 min. This technology is now under evaluation in over 30 clinical trials, which employ dissolution Dynamic Nuclear Polarization (d-DNP) to prepare a batch of the contrast agent; however, d-D...

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Veröffentlicht in:The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory Molecules, spectroscopy, kinetics, environment, & general theory, 2022-12, Vol.126 (48), p.9114-9123
Hauptverfasser: Nantogma, Shiraz, Eriksson, Shannon L., Adelabu, Isaiah, Mandzhieva, Iuliia, Browning, Austin, TomHon, Patrick, Warren, Warren S., Theis, Thomas, Goodson, Boyd M., Chekmenev, Eduard Y.
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