The Negative Effect of Preexisting Immunity on Influenza Vaccine Responses Transcends the Impact of Vaccine Formulation Type and Vaccination History

The most effective measure to induce protection from influenza is vaccination. Thus, yearly vaccination is recommended, which, together with infections, establishes diverse repertoires of B cells, antibodies, and T cells. We examined the impact of this accumulated immunity on human responses in adul...

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Veröffentlicht in:	The Journal of infectious diseases 2023-02, Vol.227 (3), p.381-390
Hauptverfasser:	Moritzky, Savannah A, Richards, Katherine A, Glover, Maryah A, Krammer, Florian, Chaves, Francisco A, Topham, David J, Branche, Angela, Nayak, Jennifer L, Sant, Andrea J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibodies Antibodies, Viral CD4-Positive T-Lymphocytes Hemagglutinin Glycoproteins, Influenza Virus Humans Influenza Vaccines Influenza, Human - prevention & control Major Vaccination
Online-Zugang:	Volltext
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