Comparative synthesis and characterization of nanocomposites using chemical and green approaches including a comparison study on in vivo and in vitro biological properties
In this study, the anti-diabetic, anti-inflammatory, anti-cytotoxic, and antibacterial effects of various substances were studied . Malachite green's photocatalytic effects were used to determine the optimised sample while it was exposed to visible light. The intended nanocomposites were create...
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| Veröffentlicht in: | Nanoscale advances 2023-01, Vol.5 (3), p.767-785 |
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| creator | G, Sabeena S, Vainath Praveen E, Pushpalakshmi G, Annadurai |
| description | In this study, the anti-diabetic, anti-inflammatory, anti-cytotoxic, and antibacterial effects of various substances were studied
. Malachite green's photocatalytic effects were used to determine the optimised sample while it was exposed to visible light. The intended nanocomposites were created without any contaminants, according to XRD data. The overall characterisation results of the green synthesis of CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)) were superior to those of the chemical synthesis of CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(C)). At the five doses examined, the green synthesis of CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)) and chemical synthesis of CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(C)) resulted in higher α-glucosidase inhibition percentages in the antidiabetic assay. HaCaT cells and MCF-7 cells were less harmful when treated with chemically synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(C)), and green synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)). From the results of the cytotoxicity tests against MCF-7 cells and HaCaT cells using the nanocomposites, the IC
values of
, green synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)), and chemically synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(C)) were calculated. This research work shows that the green synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)) have strong anti-inflammatory, antibacterial and anti-diabetic properties, as well as considerable suppression of high activation in
zebrafish embryo toxicity. The novelty of this study focused on the revelation that green synthesized nanocomposites are more affordable, environmentally friendly and biocompatible than chemically synthesized ones. |
| doi_str_mv | 10.1039/d2na00677d |
| format | Article |
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. Malachite green's photocatalytic effects were used to determine the optimised sample while it was exposed to visible light. The intended nanocomposites were created without any contaminants, according to XRD data. The overall characterisation results of the green synthesis of CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)) were superior to those of the chemical synthesis of CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(C)). At the five doses examined, the green synthesis of CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)) and chemical synthesis of CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(C)) resulted in higher α-glucosidase inhibition percentages in the antidiabetic assay. HaCaT cells and MCF-7 cells were less harmful when treated with chemically synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(C)), and green synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)). From the results of the cytotoxicity tests against MCF-7 cells and HaCaT cells using the nanocomposites, the IC
values of
, green synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)), and chemically synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(C)) were calculated. This research work shows that the green synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)) have strong anti-inflammatory, antibacterial and anti-diabetic properties, as well as considerable suppression of high activation in
zebrafish embryo toxicity. The novelty of this study focused on the revelation that green synthesized nanocomposites are more affordable, environmentally friendly and biocompatible than chemically synthesized ones.</description><identifier>ISSN: 2516-0230</identifier><identifier>EISSN: 2516-0230</identifier><identifier>DOI: 10.1039/d2na00677d</identifier><identifier>PMID: 36756509</identifier><language>eng</language><publisher>England: RSC</publisher><subject>Chemistry</subject><ispartof>Nanoscale advances, 2023-01, Vol.5 (3), p.767-785</ispartof><rights>This journal is © The Royal Society of Chemistry.</rights><rights>This journal is © The Royal Society of Chemistry 2023 RSC</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c378t-cd6ad8e03fb9efbdfc1b356a099ee8b5ce3b38561ff19ddeb07417214b4e9ed63</citedby><cites>FETCH-LOGICAL-c378t-cd6ad8e03fb9efbdfc1b356a099ee8b5ce3b38561ff19ddeb07417214b4e9ed63</cites><orcidid>0000-0002-4678-6702</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890937/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9890937/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36756509$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>G, Sabeena</creatorcontrib><creatorcontrib>S, Vainath Praveen</creatorcontrib><creatorcontrib>E, Pushpalakshmi</creatorcontrib><creatorcontrib>G, Annadurai</creatorcontrib><title>Comparative synthesis and characterization of nanocomposites using chemical and green approaches including a comparison study on in vivo and in vitro biological properties</title><title>Nanoscale advances</title><addtitle>Nanoscale Adv</addtitle><description>In this study, the anti-diabetic, anti-inflammatory, anti-cytotoxic, and antibacterial effects of various substances were studied
. Malachite green's photocatalytic effects were used to determine the optimised sample while it was exposed to visible light. The intended nanocomposites were created without any contaminants, according to XRD data. The overall characterisation results of the green synthesis of CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)) were superior to those of the chemical synthesis of CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(C)). At the five doses examined, the green synthesis of CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)) and chemical synthesis of CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(C)) resulted in higher α-glucosidase inhibition percentages in the antidiabetic assay. HaCaT cells and MCF-7 cells were less harmful when treated with chemically synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(C)), and green synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)). From the results of the cytotoxicity tests against MCF-7 cells and HaCaT cells using the nanocomposites, the IC
values of
, green synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)), and chemically synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(C)) were calculated. This research work shows that the green synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)) have strong anti-inflammatory, antibacterial and anti-diabetic properties, as well as considerable suppression of high activation in
zebrafish embryo toxicity. The novelty of this study focused on the revelation that green synthesized nanocomposites are more affordable, environmentally friendly and biocompatible than chemically synthesized ones.</description><subject>Chemistry</subject><issn>2516-0230</issn><issn>2516-0230</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNpVkc1u3CAUhVHVqonSbPoAFcuq0rRgbGM2laJJ_6Qo2aRrhOF6hsoGl4tHmr5SX7LESaNkxRHnnO8iLiFvOfvImVCfXBUMY62U7gU5rRreblgl2Msn-oScI_5ijFW8rmupXpMT0cqmbZg6JX-3cZpNMtkfgOIx5D2gR2qCo3Zf7m2G5P8UOwYaBxpMiLY0IvoMSBf0YVeCMHlrxrW1SwCBmnlO0RQDqQ92XNxdzlC7DvNYYJgXd6RF-EAP_hDX8qpzirT3cYy7FVpAM6TsAd-QV4MZEc4fzjPy8-uX2-33zdXNtx_bi6uNFbLLG-ta4zpgYugVDL0bLO9F0xqmFEDXNxZEL7qm5cPAlXPQM1lzWT6nr0GBa8UZ-XzPnZd-Amch5GRGPSc_mXTU0Xj93Al-r3fxoFWnmBKyAN4_AFL8vQBmPXm0MI4mQFxQV1LWnaoVr0r0w33UpoiYYHgcw5m-W7C-rK4v1gVflvC7pw97jP5fp_gH4Emofw</recordid><startdate>20230131</startdate><enddate>20230131</enddate><creator>G, Sabeena</creator><creator>S, Vainath Praveen</creator><creator>E, Pushpalakshmi</creator><creator>G, Annadurai</creator><general>RSC</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-4678-6702</orcidid></search><sort><creationdate>20230131</creationdate><title>Comparative synthesis and characterization of nanocomposites using chemical and green approaches including a comparison study on in vivo and in vitro biological properties</title><author>G, Sabeena ; S, Vainath Praveen ; E, Pushpalakshmi ; G, Annadurai</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c378t-cd6ad8e03fb9efbdfc1b356a099ee8b5ce3b38561ff19ddeb07417214b4e9ed63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>G, Sabeena</creatorcontrib><creatorcontrib>S, Vainath Praveen</creatorcontrib><creatorcontrib>E, Pushpalakshmi</creatorcontrib><creatorcontrib>G, Annadurai</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Nanoscale advances</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>G, Sabeena</au><au>S, Vainath Praveen</au><au>E, Pushpalakshmi</au><au>G, Annadurai</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparative synthesis and characterization of nanocomposites using chemical and green approaches including a comparison study on in vivo and in vitro biological properties</atitle><jtitle>Nanoscale advances</jtitle><addtitle>Nanoscale Adv</addtitle><date>2023-01-31</date><risdate>2023</risdate><volume>5</volume><issue>3</issue><spage>767</spage><epage>785</epage><pages>767-785</pages><issn>2516-0230</issn><eissn>2516-0230</eissn><abstract>In this study, the anti-diabetic, anti-inflammatory, anti-cytotoxic, and antibacterial effects of various substances were studied
. Malachite green's photocatalytic effects were used to determine the optimised sample while it was exposed to visible light. The intended nanocomposites were created without any contaminants, according to XRD data. The overall characterisation results of the green synthesis of CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)) were superior to those of the chemical synthesis of CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(C)). At the five doses examined, the green synthesis of CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)) and chemical synthesis of CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(C)) resulted in higher α-glucosidase inhibition percentages in the antidiabetic assay. HaCaT cells and MCF-7 cells were less harmful when treated with chemically synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(C)), and green synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)). From the results of the cytotoxicity tests against MCF-7 cells and HaCaT cells using the nanocomposites, the IC
values of
, green synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)), and chemically synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(C)) were calculated. This research work shows that the green synthesized CS/SiO
/TiO
/CeO
/Fe
O
nanocomposites (CSTCF(G)) have strong anti-inflammatory, antibacterial and anti-diabetic properties, as well as considerable suppression of high activation in
zebrafish embryo toxicity. The novelty of this study focused on the revelation that green synthesized nanocomposites are more affordable, environmentally friendly and biocompatible than chemically synthesized ones.</abstract><cop>England</cop><pub>RSC</pub><pmid>36756509</pmid><doi>10.1039/d2na00677d</doi><tpages>19</tpages><orcidid>https://orcid.org/0000-0002-4678-6702</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
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| ispartof | Nanoscale advances, 2023-01, Vol.5 (3), p.767-785 |
| issn | 2516-0230 2516-0230 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9890937 |
| source | DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Chemistry |
| title | Comparative synthesis and characterization of nanocomposites using chemical and green approaches including a comparison study on in vivo and in vitro biological properties |
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