Hyperlipidemia and Hypertension Are Associated With Intracerebral Hemorrhage Incidence: A Retrospective Study
Introduction Stroke places a huge burden on the socioeconomic systems. Hemorrhagic stroke (HS) is the second most common type of stroke and the second leading cause of disability and death. The updated data on the prevalence of intracerebral hemorrhage (ICH) stroke and related physiological risk fac...
Gespeichert in:
| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2023-01, Vol.15 (1), p.e33236-e33236 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e33236 |
|---|---|
| container_issue | 1 |
| container_start_page | e33236 |
| container_title | Curēus (Palo Alto, CA) |
| container_volume | 15 |
| creator | Almuklass, Awad M Alawad, Yousef A Alanazi, Abdulmalek S Alamro, Azzam A Alagedi, Faisal H Alshehri, Yasser A Masuadi, Emad Alotaibi, Naser Alkhateeb, Mahmoud |
| description | Introduction Stroke places a huge burden on the socioeconomic systems. Hemorrhagic stroke (HS) is the second most common type of stroke and the second leading cause of disability and death. The updated data on the prevalence of intracerebral hemorrhage (ICH) stroke and related physiological risk factors in Saudi Arabia were limited. The aim of this study was to identify the prevalence of ICH stroke and the related physiological risk factors. Methods This was a retrospective, hospital-based, and chart review study that utilized the BESTCare system at King Abdulaziz Medical City (KAMC), Riyadh, Saudi Arabia. Patients who attended the neurology department (inpatient/outpatient) between 2015 and 2020 were studied. The statistical tool JMP (JMP Inc., Cary, NC, USA) was used for data entry and analysis. Results Patient data (N = 1,870, 58.6 ± 13.87 years old) were screened for comorbidities, hypertension (66.1%), diabetes mellitus (DM) (57.7%), hyperlipidemia (28.4%), and history of an old stroke (22.3%). Ischemic stroke (IS) was more dominant than ICH stroke with ratios of 94.5% (n = 1767) versus 5.5% (n = 103), respectively. The prevalence of ICH stroke among the patients (n = 103) was 10.6%, 20.3%, 24.2%, and 28.1% in the age groups of |
| doi_str_mv | 10.7759/cureus.33236 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9888596</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2773122361</sourcerecordid><originalsourceid>FETCH-LOGICAL-c299t-db5b246949a8c541379dff68e0168404b539420b1d3885c2ef3295c1e82d3c213</originalsourceid><addsrcrecordid>eNpdkc1LJDEQxYOsqLje9rwE9rIHx81HpzvxsDDI6giCsB_sMaSTaifS3WmTtDD__WYcFddTitSPV_XqIfSJkrOmEeqbnSPM6Yxzxus9dMRoLReSyurDm_oQnaR0TwihpGGkIQfokNcN56ISR2hYbSaIvZ-8g8EbbEaHn74yjMmHES8j4GVKwXqTweG_Pq_x9ZijsRChjabHKxhCjGtzB6Vhi85o4Rwv8U_IMaQJbPaPgH_l2W0-ov3O9AlOnt9j9Ofyx--L1eLm9ur6YnmzsEypvHCtaFlVq0oZaUVFeaNc19USSPFUkaoVXFWMtNRxKYVl0HGmhKUgmeOWUX6Mvu90p7kdwFnYLtzrKfrBxI0Oxuv_O6Nf67vwqJUsgqouAl-fBWJ4mCFlPfhkoe_NCGFOmjUNp6wcfTvryzv0PsxxLPYKJUnNOaWiUKc7ypabpAjd6zKU6G2Uehelfoqy4J_fGniFX4Lj_wDV6JwD</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2780633115</pqid></control><display><type>article</type><title>Hyperlipidemia and Hypertension Are Associated With Intracerebral Hemorrhage Incidence: A Retrospective Study</title><source>PubMed Central Open Access</source><source>PubMed Central</source><creator>Almuklass, Awad M ; Alawad, Yousef A ; Alanazi, Abdulmalek S ; Alamro, Azzam A ; Alagedi, Faisal H ; Alshehri, Yasser A ; Masuadi, Emad ; Alotaibi, Naser ; Alkhateeb, Mahmoud</creator><creatorcontrib>Almuklass, Awad M ; Alawad, Yousef A ; Alanazi, Abdulmalek S ; Alamro, Azzam A ; Alagedi, Faisal H ; Alshehri, Yasser A ; Masuadi, Emad ; Alotaibi, Naser ; Alkhateeb, Mahmoud</creatorcontrib><description>Introduction Stroke places a huge burden on the socioeconomic systems. Hemorrhagic stroke (HS) is the second most common type of stroke and the second leading cause of disability and death. The updated data on the prevalence of intracerebral hemorrhage (ICH) stroke and related physiological risk factors in Saudi Arabia were limited. The aim of this study was to identify the prevalence of ICH stroke and the related physiological risk factors. Methods This was a retrospective, hospital-based, and chart review study that utilized the BESTCare system at King Abdulaziz Medical City (KAMC), Riyadh, Saudi Arabia. Patients who attended the neurology department (inpatient/outpatient) between 2015 and 2020 were studied. The statistical tool JMP (JMP Inc., Cary, NC, USA) was used for data entry and analysis. Results Patient data (N = 1,870, 58.6 ± 13.87 years old) were screened for comorbidities, hypertension (66.1%), diabetes mellitus (DM) (57.7%), hyperlipidemia (28.4%), and history of an old stroke (22.3%). Ischemic stroke (IS) was more dominant than ICH stroke with ratios of 94.5% (n = 1767) versus 5.5% (n = 103), respectively. The prevalence of ICH stroke among the patients (n = 103) was 10.6%, 20.3%, 24.2%, and 28.1% in the age groups of <40, 41-50, 51-60, and 61-70 years old, respectively. There was a significant gender effect on the distribution of both IS and ICH (p = 0.003). ICH strokes were more prevalent in males than in females. Body mass index (BMI) has no significant effect on the prevalence of IS and ICH stroke (p = 0.081). ICH stroke was significantly associated with DM (p = 0.032), hypertension (p = 0.01), and hyperlipidemia (p = 0.002). Regression analyses show that only hypertension (positive association) and hyperlipidemia (negative association) were significantly associated with the incidence of ICH stroke. Conclusion IS was more prevalent than ICH stroke. ICH strokes were more prevalent in males than in females. Also, hypertension was the most common factor leading to ICH stroke, unlike hyperlipidemia, which was revealed to be protective against ICH stroke.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.33236</identifier><identifier>PMID: 36733545</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Age groups ; Blood pressure ; Body mass index ; Cardiac arrhythmia ; Cardiovascular disease ; Diabetes ; Epidemiology/Public Health ; Females ; Gender ; Heart ; Hemorrhage ; Hyperlipidemia ; Hypertension ; Internal Medicine ; Males ; Mortality ; Neurology ; Patients ; Risk factors ; Stroke ; Transient ischemic attack</subject><ispartof>Curēus (Palo Alto, CA), 2023-01, Vol.15 (1), p.e33236-e33236</ispartof><rights>Copyright © 2023, Almuklass et al.</rights><rights>Copyright © 2023, Almuklass et al. This work is published under https://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2023, Almuklass et al. 2023 Almuklass et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c299t-db5b246949a8c541379dff68e0168404b539420b1d3885c2ef3295c1e82d3c213</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888596/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9888596/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36733545$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Almuklass, Awad M</creatorcontrib><creatorcontrib>Alawad, Yousef A</creatorcontrib><creatorcontrib>Alanazi, Abdulmalek S</creatorcontrib><creatorcontrib>Alamro, Azzam A</creatorcontrib><creatorcontrib>Alagedi, Faisal H</creatorcontrib><creatorcontrib>Alshehri, Yasser A</creatorcontrib><creatorcontrib>Masuadi, Emad</creatorcontrib><creatorcontrib>Alotaibi, Naser</creatorcontrib><creatorcontrib>Alkhateeb, Mahmoud</creatorcontrib><title>Hyperlipidemia and Hypertension Are Associated With Intracerebral Hemorrhage Incidence: A Retrospective Study</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Introduction Stroke places a huge burden on the socioeconomic systems. Hemorrhagic stroke (HS) is the second most common type of stroke and the second leading cause of disability and death. The updated data on the prevalence of intracerebral hemorrhage (ICH) stroke and related physiological risk factors in Saudi Arabia were limited. The aim of this study was to identify the prevalence of ICH stroke and the related physiological risk factors. Methods This was a retrospective, hospital-based, and chart review study that utilized the BESTCare system at King Abdulaziz Medical City (KAMC), Riyadh, Saudi Arabia. Patients who attended the neurology department (inpatient/outpatient) between 2015 and 2020 were studied. The statistical tool JMP (JMP Inc., Cary, NC, USA) was used for data entry and analysis. Results Patient data (N = 1,870, 58.6 ± 13.87 years old) were screened for comorbidities, hypertension (66.1%), diabetes mellitus (DM) (57.7%), hyperlipidemia (28.4%), and history of an old stroke (22.3%). Ischemic stroke (IS) was more dominant than ICH stroke with ratios of 94.5% (n = 1767) versus 5.5% (n = 103), respectively. The prevalence of ICH stroke among the patients (n = 103) was 10.6%, 20.3%, 24.2%, and 28.1% in the age groups of <40, 41-50, 51-60, and 61-70 years old, respectively. There was a significant gender effect on the distribution of both IS and ICH (p = 0.003). ICH strokes were more prevalent in males than in females. Body mass index (BMI) has no significant effect on the prevalence of IS and ICH stroke (p = 0.081). ICH stroke was significantly associated with DM (p = 0.032), hypertension (p = 0.01), and hyperlipidemia (p = 0.002). Regression analyses show that only hypertension (positive association) and hyperlipidemia (negative association) were significantly associated with the incidence of ICH stroke. Conclusion IS was more prevalent than ICH stroke. ICH strokes were more prevalent in males than in females. Also, hypertension was the most common factor leading to ICH stroke, unlike hyperlipidemia, which was revealed to be protective against ICH stroke.</description><subject>Age groups</subject><subject>Blood pressure</subject><subject>Body mass index</subject><subject>Cardiac arrhythmia</subject><subject>Cardiovascular disease</subject><subject>Diabetes</subject><subject>Epidemiology/Public Health</subject><subject>Females</subject><subject>Gender</subject><subject>Heart</subject><subject>Hemorrhage</subject><subject>Hyperlipidemia</subject><subject>Hypertension</subject><subject>Internal Medicine</subject><subject>Males</subject><subject>Mortality</subject><subject>Neurology</subject><subject>Patients</subject><subject>Risk factors</subject><subject>Stroke</subject><subject>Transient ischemic attack</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkc1LJDEQxYOsqLje9rwE9rIHx81HpzvxsDDI6giCsB_sMaSTaifS3WmTtDD__WYcFddTitSPV_XqIfSJkrOmEeqbnSPM6Yxzxus9dMRoLReSyurDm_oQnaR0TwihpGGkIQfokNcN56ISR2hYbSaIvZ-8g8EbbEaHn74yjMmHES8j4GVKwXqTweG_Pq_x9ZijsRChjabHKxhCjGtzB6Vhi85o4Rwv8U_IMaQJbPaPgH_l2W0-ov3O9AlOnt9j9Ofyx--L1eLm9ur6YnmzsEypvHCtaFlVq0oZaUVFeaNc19USSPFUkaoVXFWMtNRxKYVl0HGmhKUgmeOWUX6Mvu90p7kdwFnYLtzrKfrBxI0Oxuv_O6Nf67vwqJUsgqouAl-fBWJ4mCFlPfhkoe_NCGFOmjUNp6wcfTvryzv0PsxxLPYKJUnNOaWiUKc7ypabpAjd6zKU6G2Uehelfoqy4J_fGniFX4Lj_wDV6JwD</recordid><startdate>202301</startdate><enddate>202301</enddate><creator>Almuklass, Awad M</creator><creator>Alawad, Yousef A</creator><creator>Alanazi, Abdulmalek S</creator><creator>Alamro, Azzam A</creator><creator>Alagedi, Faisal H</creator><creator>Alshehri, Yasser A</creator><creator>Masuadi, Emad</creator><creator>Alotaibi, Naser</creator><creator>Alkhateeb, Mahmoud</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>202301</creationdate><title>Hyperlipidemia and Hypertension Are Associated With Intracerebral Hemorrhage Incidence: A Retrospective Study</title><author>Almuklass, Awad M ; Alawad, Yousef A ; Alanazi, Abdulmalek S ; Alamro, Azzam A ; Alagedi, Faisal H ; Alshehri, Yasser A ; Masuadi, Emad ; Alotaibi, Naser ; Alkhateeb, Mahmoud</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c299t-db5b246949a8c541379dff68e0168404b539420b1d3885c2ef3295c1e82d3c213</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Age groups</topic><topic>Blood pressure</topic><topic>Body mass index</topic><topic>Cardiac arrhythmia</topic><topic>Cardiovascular disease</topic><topic>Diabetes</topic><topic>Epidemiology/Public Health</topic><topic>Females</topic><topic>Gender</topic><topic>Heart</topic><topic>Hemorrhage</topic><topic>Hyperlipidemia</topic><topic>Hypertension</topic><topic>Internal Medicine</topic><topic>Males</topic><topic>Mortality</topic><topic>Neurology</topic><topic>Patients</topic><topic>Risk factors</topic><topic>Stroke</topic><topic>Transient ischemic attack</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Almuklass, Awad M</creatorcontrib><creatorcontrib>Alawad, Yousef A</creatorcontrib><creatorcontrib>Alanazi, Abdulmalek S</creatorcontrib><creatorcontrib>Alamro, Azzam A</creatorcontrib><creatorcontrib>Alagedi, Faisal H</creatorcontrib><creatorcontrib>Alshehri, Yasser A</creatorcontrib><creatorcontrib>Masuadi, Emad</creatorcontrib><creatorcontrib>Alotaibi, Naser</creatorcontrib><creatorcontrib>Alkhateeb, Mahmoud</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Almuklass, Awad M</au><au>Alawad, Yousef A</au><au>Alanazi, Abdulmalek S</au><au>Alamro, Azzam A</au><au>Alagedi, Faisal H</au><au>Alshehri, Yasser A</au><au>Masuadi, Emad</au><au>Alotaibi, Naser</au><au>Alkhateeb, Mahmoud</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hyperlipidemia and Hypertension Are Associated With Intracerebral Hemorrhage Incidence: A Retrospective Study</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2023-01</date><risdate>2023</risdate><volume>15</volume><issue>1</issue><spage>e33236</spage><epage>e33236</epage><pages>e33236-e33236</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Introduction Stroke places a huge burden on the socioeconomic systems. Hemorrhagic stroke (HS) is the second most common type of stroke and the second leading cause of disability and death. The updated data on the prevalence of intracerebral hemorrhage (ICH) stroke and related physiological risk factors in Saudi Arabia were limited. The aim of this study was to identify the prevalence of ICH stroke and the related physiological risk factors. Methods This was a retrospective, hospital-based, and chart review study that utilized the BESTCare system at King Abdulaziz Medical City (KAMC), Riyadh, Saudi Arabia. Patients who attended the neurology department (inpatient/outpatient) between 2015 and 2020 were studied. The statistical tool JMP (JMP Inc., Cary, NC, USA) was used for data entry and analysis. Results Patient data (N = 1,870, 58.6 ± 13.87 years old) were screened for comorbidities, hypertension (66.1%), diabetes mellitus (DM) (57.7%), hyperlipidemia (28.4%), and history of an old stroke (22.3%). Ischemic stroke (IS) was more dominant than ICH stroke with ratios of 94.5% (n = 1767) versus 5.5% (n = 103), respectively. The prevalence of ICH stroke among the patients (n = 103) was 10.6%, 20.3%, 24.2%, and 28.1% in the age groups of <40, 41-50, 51-60, and 61-70 years old, respectively. There was a significant gender effect on the distribution of both IS and ICH (p = 0.003). ICH strokes were more prevalent in males than in females. Body mass index (BMI) has no significant effect on the prevalence of IS and ICH stroke (p = 0.081). ICH stroke was significantly associated with DM (p = 0.032), hypertension (p = 0.01), and hyperlipidemia (p = 0.002). Regression analyses show that only hypertension (positive association) and hyperlipidemia (negative association) were significantly associated with the incidence of ICH stroke. Conclusion IS was more prevalent than ICH stroke. ICH strokes were more prevalent in males than in females. Also, hypertension was the most common factor leading to ICH stroke, unlike hyperlipidemia, which was revealed to be protective against ICH stroke.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>36733545</pmid><doi>10.7759/cureus.33236</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2168-8184 |
| ispartof | Curēus (Palo Alto, CA), 2023-01, Vol.15 (1), p.e33236-e33236 |
| issn | 2168-8184 2168-8184 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9888596 |
| source | PubMed Central Open Access; PubMed Central |
| subjects | Age groups Blood pressure Body mass index Cardiac arrhythmia Cardiovascular disease Diabetes Epidemiology/Public Health Females Gender Heart Hemorrhage Hyperlipidemia Hypertension Internal Medicine Males Mortality Neurology Patients Risk factors Stroke Transient ischemic attack |
| title | Hyperlipidemia and Hypertension Are Associated With Intracerebral Hemorrhage Incidence: A Retrospective Study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T04%3A40%3A42IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Hyperlipidemia%20and%20Hypertension%20Are%20Associated%20With%20Intracerebral%20Hemorrhage%20Incidence:%20A%20Retrospective%20Study&rft.jtitle=Cur%C4%93us%20(Palo%20Alto,%20CA)&rft.au=Almuklass,%20Awad%20M&rft.date=2023-01&rft.volume=15&rft.issue=1&rft.spage=e33236&rft.epage=e33236&rft.pages=e33236-e33236&rft.issn=2168-8184&rft.eissn=2168-8184&rft_id=info:doi/10.7759/cureus.33236&rft_dat=%3Cproquest_pubme%3E2773122361%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2780633115&rft_id=info:pmid/36733545&rfr_iscdi=true |