Associations between air pollutants and hospital admissions for chronic obstructive pulmonary disease in Jinan: potential benefits from air quality improvements
Evidence between air pollution and chronic obstructive pulmonary disease (COPD) is inconsistent and limited in China. In this study, we aim to examine the associations between air pollutants and hospital admissions for COPD, hoping to provide practical advice for prevention and control of COPD. Hosp...
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description | Evidence between air pollution and chronic obstructive pulmonary disease (COPD) is inconsistent and limited in China. In this study, we aim to examine the associations between air pollutants and hospital admissions for COPD, hoping to provide practical advice for prevention and control of COPD. Hospital admissions for COPD were collected from a Grade-A tertiary hospital in Jinan from 2014 to 2020. A generalized additive model (GAM) was used to examine the associations between air pollutants and hospital admissions for COPD. Stratified analysis was also conducted for gender, age (20–74 and ≥75 years), and season (warm and cold). The avoidable number of COPD hospital admissions was calculated when air pollutants were controlled under national and WHO standards. Over the study period, a total of 4,012 hospital admissions for COPD were recorded. The daily hospital admissions of COPD increased by 2.36% (95%
CI
: 0.13–4.65%) and 2.39% (95%
CI
: 0.19–4.65%) for per 10 μg/m
3
increase of NO
2
and SO
2
concentrations at lag2, respectively. There was no statistically significant difference in health effects caused by increased concentrations of PM
2.5
, PM
10
, CO, and O
3
. The health effects of increased SO
2
concentration were stronger in women, the ≥75 years old people and the cold season. About 2 (95%
CI
: 0–3), 64 (95%
CI
: 4–132) and 86 (95%
CI
: 6–177) COPD admissions would be avoided when the SO
2
concentration was controlled below the NAAQS-II (150 μg/m
3
), NAAQS-I (50 μg/m
3
), and WHO’s AQG2021 standard (40 μg/m
3
), respectively. These findings suggest that short-term exposure to NO
2
and SO
2
was associated with increased risks of daily COPD admissions, especially for females and the elderly. The control of SO
2
and NO
2
under the national and WHO standards could avoid more COPD admissions and obtain greater health benefits. |
doi_str_mv | 10.1007/s11356-023-25567-8 |
format | Article |
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CI
: 0.13–4.65%) and 2.39% (95%
CI
: 0.19–4.65%) for per 10 μg/m
3
increase of NO
2
and SO
2
concentrations at lag2, respectively. There was no statistically significant difference in health effects caused by increased concentrations of PM
2.5
, PM
10
, CO, and O
3
. The health effects of increased SO
2
concentration were stronger in women, the ≥75 years old people and the cold season. About 2 (95%
CI
: 0–3), 64 (95%
CI
: 4–132) and 86 (95%
CI
: 6–177) COPD admissions would be avoided when the SO
2
concentration was controlled below the NAAQS-II (150 μg/m
3
), NAAQS-I (50 μg/m
3
), and WHO’s AQG2021 standard (40 μg/m
3
), respectively. These findings suggest that short-term exposure to NO
2
and SO
2
was associated with increased risks of daily COPD admissions, especially for females and the elderly. The control of SO
2
and NO
2
under the national and WHO standards could avoid more COPD admissions and obtain greater health benefits.</description><identifier>ISSN: 1614-7499</identifier><identifier>ISSN: 0944-1344</identifier><identifier>EISSN: 1614-7499</identifier><identifier>DOI: 10.1007/s11356-023-25567-8</identifier><identifier>PMID: 36717420</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>acute exposure ; Aged ; air ; Air Pollutants - analysis ; Air pollution ; Air Pollution - analysis ; Air quality ; Aquatic Pollution ; Atmospheric Protection/Air Quality Control/Air Pollution ; China ; Chronic obstructive pulmonary disease ; cold ; Cold season ; Earth and Environmental Science ; Ecotoxicology ; elderly ; Environment ; Environmental Chemistry ; Environmental Health ; Environmental science ; Female ; gender ; Hospitals ; Humans ; Lung diseases ; Nitrogen dioxide ; Nitrogen Dioxide - analysis ; Obstructive lung disease ; Older people ; Outdoor air quality ; Particulate matter ; Particulate Matter - analysis ; Patient admissions ; Pollutants ; Pollution control ; Pulmonary Disease, Chronic Obstructive - epidemiology ; Quality Improvement ; Research Article ; respiratory tract diseases ; Statistical analysis ; Sulfur dioxide ; Waste Water Technology ; Water Management ; Water Pollution Control</subject><ispartof>Environmental science and pollution research international, 2023-04, Vol.30 (16), p.46435-46445</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.</rights><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c507t-336f00bf556cbeb85eef87336708b1f71912d3b1f4ad59dc9589eddddc0ebb0e3</citedby><cites>FETCH-LOGICAL-c507t-336f00bf556cbeb85eef87336708b1f71912d3b1f4ad59dc9589eddddc0ebb0e3</cites><orcidid>0000-0001-7771-2725</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11356-023-25567-8$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11356-023-25567-8$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,776,780,881,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36717420$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cheng, Chuanlong</creatorcontrib><creatorcontrib>Han, Chuang</creatorcontrib><creatorcontrib>Fang, Qidi</creatorcontrib><creatorcontrib>Liu, Ying</creatorcontrib><creatorcontrib>Chi, Xiangyu</creatorcontrib><creatorcontrib>Li, Xiujun</creatorcontrib><title>Associations between air pollutants and hospital admissions for chronic obstructive pulmonary disease in Jinan: potential benefits from air quality improvements</title><title>Environmental science and pollution research international</title><addtitle>Environ Sci Pollut Res</addtitle><addtitle>Environ Sci Pollut Res Int</addtitle><description>Evidence between air pollution and chronic obstructive pulmonary disease (COPD) is inconsistent and limited in China. In this study, we aim to examine the associations between air pollutants and hospital admissions for COPD, hoping to provide practical advice for prevention and control of COPD. Hospital admissions for COPD were collected from a Grade-A tertiary hospital in Jinan from 2014 to 2020. A generalized additive model (GAM) was used to examine the associations between air pollutants and hospital admissions for COPD. Stratified analysis was also conducted for gender, age (20–74 and ≥75 years), and season (warm and cold). The avoidable number of COPD hospital admissions was calculated when air pollutants were controlled under national and WHO standards. Over the study period, a total of 4,012 hospital admissions for COPD were recorded. The daily hospital admissions of COPD increased by 2.36% (95%
CI
: 0.13–4.65%) and 2.39% (95%
CI
: 0.19–4.65%) for per 10 μg/m
3
increase of NO
2
and SO
2
concentrations at lag2, respectively. There was no statistically significant difference in health effects caused by increased concentrations of PM
2.5
, PM
10
, CO, and O
3
. The health effects of increased SO
2
concentration were stronger in women, the ≥75 years old people and the cold season. About 2 (95%
CI
: 0–3), 64 (95%
CI
: 4–132) and 86 (95%
CI
: 6–177) COPD admissions would be avoided when the SO
2
concentration was controlled below the NAAQS-II (150 μg/m
3
), NAAQS-I (50 μg/m
3
), and WHO’s AQG2021 standard (40 μg/m
3
), respectively. These findings suggest that short-term exposure to NO
2
and SO
2
was associated with increased risks of daily COPD admissions, especially for females and the elderly. The control of SO
2
and NO
2
under the national and WHO standards could avoid more COPD admissions and obtain greater health benefits.</description><subject>acute exposure</subject><subject>Aged</subject><subject>air</subject><subject>Air Pollutants - analysis</subject><subject>Air pollution</subject><subject>Air Pollution - analysis</subject><subject>Air quality</subject><subject>Aquatic Pollution</subject><subject>Atmospheric Protection/Air Quality Control/Air Pollution</subject><subject>China</subject><subject>Chronic obstructive pulmonary disease</subject><subject>cold</subject><subject>Cold season</subject><subject>Earth and Environmental Science</subject><subject>Ecotoxicology</subject><subject>elderly</subject><subject>Environment</subject><subject>Environmental Chemistry</subject><subject>Environmental Health</subject><subject>Environmental science</subject><subject>Female</subject><subject>gender</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Lung diseases</subject><subject>Nitrogen dioxide</subject><subject>Nitrogen Dioxide - analysis</subject><subject>Obstructive lung disease</subject><subject>Older people</subject><subject>Outdoor air quality</subject><subject>Particulate matter</subject><subject>Particulate Matter - analysis</subject><subject>Patient admissions</subject><subject>Pollutants</subject><subject>Pollution control</subject><subject>Pulmonary Disease, Chronic Obstructive - epidemiology</subject><subject>Quality Improvement</subject><subject>Research Article</subject><subject>respiratory tract diseases</subject><subject>Statistical analysis</subject><subject>Sulfur dioxide</subject><subject>Waste Water Technology</subject><subject>Water Management</subject><subject>Water Pollution Control</subject><issn>1614-7499</issn><issn>0944-1344</issn><issn>1614-7499</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFks1u1TAQhSMEoqXwAiyQJTZsAv5J4pgFUlVBC6rEBtaW7Ux6XSV26nFu1bfhUXHvLaWwAG888nxzxjM6VfWS0beMUvkOGRNtV1Muat62naz7R9Uh61hTy0apxw_ig-oZ4iWlnCoun1YHopNMNpweVj-OEaPzJvsYkFjI1wCBGJ_IEqdpzSZkJCYMZBNx8dlMxAyzR9zhY0zEbVIM3pFoMafVZb8FsqzTHINJN2TwCAaB-EC--GDC-yKbIWRfhCwEGH2RH1Ocdy2vVjP5fEP8vKS4hbmA-Lx6MpoJ4cXdfVR9__Tx28lZff719PPJ8XntWipzLUQ3UmrHsgdnwfYtwNjL8ippb9komWJ8ECVqzNCqwam2VzCU4yhYS0EcVR_2ustqZxhc6Z3MpJfk5zKIjsbrPzPBb_RF3GrV95I3XRF4cyeQ4tUKmHXZk4NpMgHiilrQhgrZdlT8F-VSMiGE4rfo67_Qy7imUDaheU-l6kTTyELxPeVSREww3v-bUX3rFb33ii5e0Tuv6L4UvXo48X3JL3MUQOwBLKlwAel373_I_gTx49A-</recordid><startdate>20230401</startdate><enddate>20230401</enddate><creator>Cheng, Chuanlong</creator><creator>Han, Chuang</creator><creator>Fang, Qidi</creator><creator>Liu, Ying</creator><creator>Chi, Xiangyu</creator><creator>Li, Xiujun</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7SN</scope><scope>7T7</scope><scope>7TV</scope><scope>7U7</scope><scope>7WY</scope><scope>7WZ</scope><scope>7X7</scope><scope>7XB</scope><scope>87Z</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8FL</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BEZIV</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FRNLG</scope><scope>FYUFA</scope><scope>F~G</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K60</scope><scope>K6~</scope><scope>K9.</scope><scope>L.-</scope><scope>M0C</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7N</scope><scope>P64</scope><scope>PATMY</scope><scope>PQBIZ</scope><scope>PQBZA</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PYCSY</scope><scope>Q9U</scope><scope>7X8</scope><scope>7S9</scope><scope>L.6</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-7771-2725</orcidid></search><sort><creationdate>20230401</creationdate><title>Associations between air pollutants and hospital admissions for chronic obstructive pulmonary disease in Jinan: potential benefits from air quality improvements</title><author>Cheng, Chuanlong ; Han, Chuang ; Fang, Qidi ; Liu, Ying ; Chi, Xiangyu ; Li, Xiujun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c507t-336f00bf556cbeb85eef87336708b1f71912d3b1f4ad59dc9589eddddc0ebb0e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>acute exposure</topic><topic>Aged</topic><topic>air</topic><topic>Air Pollutants - analysis</topic><topic>Air pollution</topic><topic>Air Pollution - analysis</topic><topic>Air quality</topic><topic>Aquatic Pollution</topic><topic>Atmospheric Protection/Air Quality Control/Air Pollution</topic><topic>China</topic><topic>Chronic obstructive pulmonary disease</topic><topic>cold</topic><topic>Cold season</topic><topic>Earth and Environmental Science</topic><topic>Ecotoxicology</topic><topic>elderly</topic><topic>Environment</topic><topic>Environmental Chemistry</topic><topic>Environmental Health</topic><topic>Environmental science</topic><topic>Female</topic><topic>gender</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Lung diseases</topic><topic>Nitrogen dioxide</topic><topic>Nitrogen Dioxide - analysis</topic><topic>Obstructive lung disease</topic><topic>Older people</topic><topic>Outdoor air quality</topic><topic>Particulate matter</topic><topic>Particulate Matter - analysis</topic><topic>Patient admissions</topic><topic>Pollutants</topic><topic>Pollution control</topic><topic>Pulmonary Disease, Chronic Obstructive - epidemiology</topic><topic>Quality Improvement</topic><topic>Research Article</topic><topic>respiratory tract diseases</topic><topic>Statistical analysis</topic><topic>Sulfur dioxide</topic><topic>Waste Water Technology</topic><topic>Water Management</topic><topic>Water Pollution Control</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cheng, Chuanlong</creatorcontrib><creatorcontrib>Han, Chuang</creatorcontrib><creatorcontrib>Fang, Qidi</creatorcontrib><creatorcontrib>Liu, Ying</creatorcontrib><creatorcontrib>Chi, Xiangyu</creatorcontrib><creatorcontrib>Li, Xiujun</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Ecology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Pollution Abstracts</collection><collection>Toxicology Abstracts</collection><collection>ABI/INFORM Collection</collection><collection>ABI/INFORM Global (PDF only)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ABI/INFORM Global (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ABI/INFORM Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Business Premium Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Business Premium Collection (Alumni)</collection><collection>Health Research Premium Collection</collection><collection>ABI/INFORM Global (Corporate)</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Business Collection (Alumni Edition)</collection><collection>ProQuest Business Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ABI/INFORM Professional Advanced</collection><collection>ABI/INFORM Global</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>ProQuest One Business</collection><collection>ProQuest One Business (Alumni)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Environmental Science Collection</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>AGRICOLA</collection><collection>AGRICOLA - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Environmental science and pollution research international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cheng, Chuanlong</au><au>Han, Chuang</au><au>Fang, Qidi</au><au>Liu, Ying</au><au>Chi, Xiangyu</au><au>Li, Xiujun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Associations between air pollutants and hospital admissions for chronic obstructive pulmonary disease in Jinan: potential benefits from air quality improvements</atitle><jtitle>Environmental science and pollution research international</jtitle><stitle>Environ Sci Pollut Res</stitle><addtitle>Environ Sci Pollut Res Int</addtitle><date>2023-04-01</date><risdate>2023</risdate><volume>30</volume><issue>16</issue><spage>46435</spage><epage>46445</epage><pages>46435-46445</pages><issn>1614-7499</issn><issn>0944-1344</issn><eissn>1614-7499</eissn><abstract>Evidence between air pollution and chronic obstructive pulmonary disease (COPD) is inconsistent and limited in China. In this study, we aim to examine the associations between air pollutants and hospital admissions for COPD, hoping to provide practical advice for prevention and control of COPD. Hospital admissions for COPD were collected from a Grade-A tertiary hospital in Jinan from 2014 to 2020. A generalized additive model (GAM) was used to examine the associations between air pollutants and hospital admissions for COPD. Stratified analysis was also conducted for gender, age (20–74 and ≥75 years), and season (warm and cold). The avoidable number of COPD hospital admissions was calculated when air pollutants were controlled under national and WHO standards. Over the study period, a total of 4,012 hospital admissions for COPD were recorded. The daily hospital admissions of COPD increased by 2.36% (95%
CI
: 0.13–4.65%) and 2.39% (95%
CI
: 0.19–4.65%) for per 10 μg/m
3
increase of NO
2
and SO
2
concentrations at lag2, respectively. There was no statistically significant difference in health effects caused by increased concentrations of PM
2.5
, PM
10
, CO, and O
3
. The health effects of increased SO
2
concentration were stronger in women, the ≥75 years old people and the cold season. About 2 (95%
CI
: 0–3), 64 (95%
CI
: 4–132) and 86 (95%
CI
: 6–177) COPD admissions would be avoided when the SO
2
concentration was controlled below the NAAQS-II (150 μg/m
3
), NAAQS-I (50 μg/m
3
), and WHO’s AQG2021 standard (40 μg/m
3
), respectively. These findings suggest that short-term exposure to NO
2
and SO
2
was associated with increased risks of daily COPD admissions, especially for females and the elderly. The control of SO
2
and NO
2
under the national and WHO standards could avoid more COPD admissions and obtain greater health benefits.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>36717420</pmid><doi>10.1007/s11356-023-25567-8</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0001-7771-2725</orcidid><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1614-7499 |
ispartof | Environmental science and pollution research international, 2023-04, Vol.30 (16), p.46435-46445 |
issn | 1614-7499 0944-1344 1614-7499 |
language | eng |
recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9887246 |
source | MEDLINE; SpringerLink Journals - AutoHoldings |
subjects | acute exposure Aged air Air Pollutants - analysis Air pollution Air Pollution - analysis Air quality Aquatic Pollution Atmospheric Protection/Air Quality Control/Air Pollution China Chronic obstructive pulmonary disease cold Cold season Earth and Environmental Science Ecotoxicology elderly Environment Environmental Chemistry Environmental Health Environmental science Female gender Hospitals Humans Lung diseases Nitrogen dioxide Nitrogen Dioxide - analysis Obstructive lung disease Older people Outdoor air quality Particulate matter Particulate Matter - analysis Patient admissions Pollutants Pollution control Pulmonary Disease, Chronic Obstructive - epidemiology Quality Improvement Research Article respiratory tract diseases Statistical analysis Sulfur dioxide Waste Water Technology Water Management Water Pollution Control |
title | Associations between air pollutants and hospital admissions for chronic obstructive pulmonary disease in Jinan: potential benefits from air quality improvements |
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