Comparison of pathogenicity of 4 porcine circovirus type 2 (PCV2) genotypes (2a, 2b, 2d, and 2e) in experimentally infected pigs

The objective of the current study was to compare the virulence of four porcine circovirus type 2 (PCV2) genotypes (PCV2a, 2b, 2d, and 2e) in pigs. Pigs were inoculated at 42 days of age with one of four PCV2 genotypes, then necropsied at 63 days of age. PCV2 genotype groups were evaluated through a...

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Veröffentlicht in:	Journal of Veterinary Medical Science 2023, Vol.85(1), pp.83-87
Hauptverfasser:	CHO, Hyejean, OH, Taehwan, SUH, Jeongmin, CHAE, Chanhee
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Viral Blood Circoviridae Infections - veterinary Circovirus - genetics Genotype Genotypes Lymph nodes Pathogenicity porcine circovirus type 2a porcine circovirus type 2b porcine circovirus type 2d porcine circovirus type 2e Swine Swine Diseases Virology Virulence
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Zusammenfassung:	The objective of the current study was to compare the virulence of four porcine circovirus type 2 (PCV2) genotypes (PCV2a, 2b, 2d, and 2e) in pigs. Pigs were inoculated at 42 days of age with one of four PCV2 genotypes, then necropsied at 63 days of age. PCV2 genotype groups were evaluated through a comparison of clinical outcomes, antibody titers, level of PCV2 loads in blood and lymph nodes, and lymphoid lesion severity. Statistical differences did not occur between the evaluated genotype groups. Pigs inoculated with PCV2a, PCV2b, or PCV2d had a significantly (P
ISSN:	0916-7250 1347-7439
DOI:	10.1292/jvms.22-0202