Cancer cell states recur across tumor types and form specific interactions with the tumor microenvironment

Transcriptional heterogeneity among malignant cells of a tumor has been studied in individual cancer types and shown to be organized into cancer cell states; however, it remains unclear to what extent these states span tumor types, constituting general features of cancer. Here, we perform a pan-canc...

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Veröffentlicht in:Nature genetics 2022-08, Vol.54 (8), p.1192-1201
Hauptverfasser: Barkley, Dalia, Moncada, Reuben, Pour, Maayan, Liberman, Deborah A., Dryg, Ian, Werba, Gregor, Wang, Wei, Baron, Maayan, Rao, Anjali, Xia, Bo, França, Gustavo S., Weil, Alejandro, Delair, Deborah F., Hajdu, Cristina, Lund, Amanda W., Osman, Iman, Yanai, Itai
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Sprache:eng
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