A Rare Case of Endocervical Adenocarcinoma of Gastric Type
Gastric adenocarcinoma of the cervix (GAC) represents a rare mucinous endocervical cancer unrelated to human papillomavirus (HPV). GAC has been found to comprise approximately 10% of cervical adenocarcinomas internationally. As more cases have been identified, GAC has been further classified into su...
Gespeichert in:
| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2022-12, Vol.14 (12), p.e33059 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 12 |
| container_start_page | e33059 |
| container_title | Curēus (Palo Alto, CA) |
| container_volume | 14 |
| creator | Mekheal, Erinie Kania, Brooke E Kapoor, Ashima Kumar, Vinod Maroules, Michael |
| description | Gastric adenocarcinoma of the cervix (GAC) represents a rare mucinous endocervical cancer unrelated to human papillomavirus (HPV). GAC has been found to comprise approximately 10% of cervical adenocarcinomas internationally. As more cases have been identified, GAC has been further classified into subtypes such as poorly differentiated versus well-differentiated (also referred to as mucinous or adenoma malignum). This cancer coined the term "gastric" subtype due to its similarity to the pancreaticobiliary and gastric tissue lining. With limited data and similar histological and genetic features of GAC, this malignancy poses a challenge for clinicians when differentiating between metastasis from the gastrointestinal tract and GAC. Here, we present a case of a 55-year-old female who presented with postmenopausal bleeding and was found to have stage IA1 endocervical adenocarcinoma of gastric subtype. The purpose of this article is to introduce a rare type of gastric adenocarcinoma with a unique site of origin in order to better understand this disease process and potentially help clinicians better diagnose and treat patients with this malignancy in the future. |
| doi_str_mv | 10.7759/cureus.33059 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9882999</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2771240444</sourcerecordid><originalsourceid>FETCH-LOGICAL-c266t-8b930d4e2d4044366b6efca9726dc9f96eaa020b62f9a46db30a90cde0c3491f3</originalsourceid><addsrcrecordid>eNpVkE1LAzEQhoMottTePMuCV7dOPppsPAil1CoUBKnnkE2yuqXd1GS30H_fra2lnmZgHt55eRC6xTAQYigfTRNcEweUwlBeoC7BPEsznLHLs72D-jEuAACDICDgGnUoFwQPJeuip1HyoYNLxjq6xBfJpLLeuLApjV4mI-sqb3QwZeVXen-e6liH0iTz7drdoKtCL6PrH2cPfb5M5uPXdPY-fRuPZqkhnNdplksKljliGTBGOc-5K4yWgnBrZCG50xoI5JwUUjNucwpagrEODGUSF7SHng-56yZfOWtcVQe9VOtQrnTYKq9L9f9Sld_qy2-UzDIipWwD7o8Bwf80LtZq4ZtQtZ0VEQKTfS_WUg8HygQfY3DF6QMGtZetDrLVr-wWvztvdYL_1NIdcpB7WA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2771240444</pqid></control><display><type>article</type><title>A Rare Case of Endocervical Adenocarcinoma of Gastric Type</title><source>PubMed Central Open Access</source><source>PubMed Central</source><creator>Mekheal, Erinie ; Kania, Brooke E ; Kapoor, Ashima ; Kumar, Vinod ; Maroules, Michael</creator><creatorcontrib>Mekheal, Erinie ; Kania, Brooke E ; Kapoor, Ashima ; Kumar, Vinod ; Maroules, Michael</creatorcontrib><description>Gastric adenocarcinoma of the cervix (GAC) represents a rare mucinous endocervical cancer unrelated to human papillomavirus (HPV). GAC has been found to comprise approximately 10% of cervical adenocarcinomas internationally. As more cases have been identified, GAC has been further classified into subtypes such as poorly differentiated versus well-differentiated (also referred to as mucinous or adenoma malignum). This cancer coined the term "gastric" subtype due to its similarity to the pancreaticobiliary and gastric tissue lining. With limited data and similar histological and genetic features of GAC, this malignancy poses a challenge for clinicians when differentiating between metastasis from the gastrointestinal tract and GAC. Here, we present a case of a 55-year-old female who presented with postmenopausal bleeding and was found to have stage IA1 endocervical adenocarcinoma of gastric subtype. The purpose of this article is to introduce a rare type of gastric adenocarcinoma with a unique site of origin in order to better understand this disease process and potentially help clinicians better diagnose and treat patients with this malignancy in the future.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.33059</identifier><identifier>PMID: 36721594</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Biopsy ; Cancer therapies ; Case reports ; Cervical cancer ; Cervix ; Classification ; Cysts ; Cytoplasm ; Disease ; Fallopian tubes ; Gastric cancer ; Human papillomavirus ; Hysterectomy ; Internal Medicine ; Lymphatic system ; Medical prognosis ; Medical screening ; Metastasis ; Oncology ; Oophorectomy ; Ovaries ; Pathology ; Patients ; Radiation ; Tumors ; Vagina</subject><ispartof>Curēus (Palo Alto, CA), 2022-12, Vol.14 (12), p.e33059</ispartof><rights>Copyright © 2022, Mekheal et al.</rights><rights>Copyright © 2022, Mekheal et al. This work is published under https://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2022, Mekheal et al. 2022 Mekheal et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c266t-8b930d4e2d4044366b6efca9726dc9f96eaa020b62f9a46db30a90cde0c3491f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882999/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882999/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36721594$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mekheal, Erinie</creatorcontrib><creatorcontrib>Kania, Brooke E</creatorcontrib><creatorcontrib>Kapoor, Ashima</creatorcontrib><creatorcontrib>Kumar, Vinod</creatorcontrib><creatorcontrib>Maroules, Michael</creatorcontrib><title>A Rare Case of Endocervical Adenocarcinoma of Gastric Type</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Gastric adenocarcinoma of the cervix (GAC) represents a rare mucinous endocervical cancer unrelated to human papillomavirus (HPV). GAC has been found to comprise approximately 10% of cervical adenocarcinomas internationally. As more cases have been identified, GAC has been further classified into subtypes such as poorly differentiated versus well-differentiated (also referred to as mucinous or adenoma malignum). This cancer coined the term "gastric" subtype due to its similarity to the pancreaticobiliary and gastric tissue lining. With limited data and similar histological and genetic features of GAC, this malignancy poses a challenge for clinicians when differentiating between metastasis from the gastrointestinal tract and GAC. Here, we present a case of a 55-year-old female who presented with postmenopausal bleeding and was found to have stage IA1 endocervical adenocarcinoma of gastric subtype. The purpose of this article is to introduce a rare type of gastric adenocarcinoma with a unique site of origin in order to better understand this disease process and potentially help clinicians better diagnose and treat patients with this malignancy in the future.</description><subject>Biopsy</subject><subject>Cancer therapies</subject><subject>Case reports</subject><subject>Cervical cancer</subject><subject>Cervix</subject><subject>Classification</subject><subject>Cysts</subject><subject>Cytoplasm</subject><subject>Disease</subject><subject>Fallopian tubes</subject><subject>Gastric cancer</subject><subject>Human papillomavirus</subject><subject>Hysterectomy</subject><subject>Internal Medicine</subject><subject>Lymphatic system</subject><subject>Medical prognosis</subject><subject>Medical screening</subject><subject>Metastasis</subject><subject>Oncology</subject><subject>Oophorectomy</subject><subject>Ovaries</subject><subject>Pathology</subject><subject>Patients</subject><subject>Radiation</subject><subject>Tumors</subject><subject>Vagina</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpVkE1LAzEQhoMottTePMuCV7dOPppsPAil1CoUBKnnkE2yuqXd1GS30H_fra2lnmZgHt55eRC6xTAQYigfTRNcEweUwlBeoC7BPEsznLHLs72D-jEuAACDICDgGnUoFwQPJeuip1HyoYNLxjq6xBfJpLLeuLApjV4mI-sqb3QwZeVXen-e6liH0iTz7drdoKtCL6PrH2cPfb5M5uPXdPY-fRuPZqkhnNdplksKljliGTBGOc-5K4yWgnBrZCG50xoI5JwUUjNucwpagrEODGUSF7SHng-56yZfOWtcVQe9VOtQrnTYKq9L9f9Sld_qy2-UzDIipWwD7o8Bwf80LtZq4ZtQtZ0VEQKTfS_WUg8HygQfY3DF6QMGtZetDrLVr-wWvztvdYL_1NIdcpB7WA</recordid><startdate>20221228</startdate><enddate>20221228</enddate><creator>Mekheal, Erinie</creator><creator>Kania, Brooke E</creator><creator>Kapoor, Ashima</creator><creator>Kumar, Vinod</creator><creator>Maroules, Michael</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>5PM</scope></search><sort><creationdate>20221228</creationdate><title>A Rare Case of Endocervical Adenocarcinoma of Gastric Type</title><author>Mekheal, Erinie ; Kania, Brooke E ; Kapoor, Ashima ; Kumar, Vinod ; Maroules, Michael</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c266t-8b930d4e2d4044366b6efca9726dc9f96eaa020b62f9a46db30a90cde0c3491f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Biopsy</topic><topic>Cancer therapies</topic><topic>Case reports</topic><topic>Cervical cancer</topic><topic>Cervix</topic><topic>Classification</topic><topic>Cysts</topic><topic>Cytoplasm</topic><topic>Disease</topic><topic>Fallopian tubes</topic><topic>Gastric cancer</topic><topic>Human papillomavirus</topic><topic>Hysterectomy</topic><topic>Internal Medicine</topic><topic>Lymphatic system</topic><topic>Medical prognosis</topic><topic>Medical screening</topic><topic>Metastasis</topic><topic>Oncology</topic><topic>Oophorectomy</topic><topic>Ovaries</topic><topic>Pathology</topic><topic>Patients</topic><topic>Radiation</topic><topic>Tumors</topic><topic>Vagina</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mekheal, Erinie</creatorcontrib><creatorcontrib>Kania, Brooke E</creatorcontrib><creatorcontrib>Kapoor, Ashima</creatorcontrib><creatorcontrib>Kumar, Vinod</creatorcontrib><creatorcontrib>Maroules, Michael</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mekheal, Erinie</au><au>Kania, Brooke E</au><au>Kapoor, Ashima</au><au>Kumar, Vinod</au><au>Maroules, Michael</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Rare Case of Endocervical Adenocarcinoma of Gastric Type</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2022-12-28</date><risdate>2022</risdate><volume>14</volume><issue>12</issue><spage>e33059</spage><pages>e33059-</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Gastric adenocarcinoma of the cervix (GAC) represents a rare mucinous endocervical cancer unrelated to human papillomavirus (HPV). GAC has been found to comprise approximately 10% of cervical adenocarcinomas internationally. As more cases have been identified, GAC has been further classified into subtypes such as poorly differentiated versus well-differentiated (also referred to as mucinous or adenoma malignum). This cancer coined the term "gastric" subtype due to its similarity to the pancreaticobiliary and gastric tissue lining. With limited data and similar histological and genetic features of GAC, this malignancy poses a challenge for clinicians when differentiating between metastasis from the gastrointestinal tract and GAC. Here, we present a case of a 55-year-old female who presented with postmenopausal bleeding and was found to have stage IA1 endocervical adenocarcinoma of gastric subtype. The purpose of this article is to introduce a rare type of gastric adenocarcinoma with a unique site of origin in order to better understand this disease process and potentially help clinicians better diagnose and treat patients with this malignancy in the future.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>36721594</pmid><doi>10.7759/cureus.33059</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2168-8184 |
| ispartof | Curēus (Palo Alto, CA), 2022-12, Vol.14 (12), p.e33059 |
| issn | 2168-8184 2168-8184 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9882999 |
| source | PubMed Central Open Access; PubMed Central |
| subjects | Biopsy Cancer therapies Case reports Cervical cancer Cervix Classification Cysts Cytoplasm Disease Fallopian tubes Gastric cancer Human papillomavirus Hysterectomy Internal Medicine Lymphatic system Medical prognosis Medical screening Metastasis Oncology Oophorectomy Ovaries Pathology Patients Radiation Tumors Vagina |
| title | A Rare Case of Endocervical Adenocarcinoma of Gastric Type |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-12T18%3A35%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20Rare%20Case%20of%20Endocervical%20Adenocarcinoma%20of%20Gastric%20Type&rft.jtitle=Cur%C4%93us%20(Palo%20Alto,%20CA)&rft.au=Mekheal,%20Erinie&rft.date=2022-12-28&rft.volume=14&rft.issue=12&rft.spage=e33059&rft.pages=e33059-&rft.issn=2168-8184&rft.eissn=2168-8184&rft_id=info:doi/10.7759/cureus.33059&rft_dat=%3Cproquest_pubme%3E2771240444%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2771240444&rft_id=info:pmid/36721594&rfr_iscdi=true |