Molecular architecture and oligomerization of Candida glabrata Cdc13 underpin its telomeric DNA-binding and unfolding activity

The CST complex is a key player in telomere replication and stability, which in yeast comprises Cdc13, Stn1 and Ten1. While Stn1 and Ten1 are very well conserved across species, Cdc13 does not resemble its mammalian counterpart CTC1 either in sequence or domain organization, and Cdc13 but not CTC1 d...

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Veröffentlicht in:	Nucleic acids research 2023-01, Vol.51 (2), p.668-686
Hauptverfasser:	Coloma, Javier, Gonzalez-Rodriguez, Nayim, Balaguer, Francisco A, Gmurczyk, Karolina, Aicart-Ramos, Clara, Nuero, Óscar M, Luque-Ortega, Juan Román, Calugaru, Kimberly, Lue, Neal F, Moreno-Herrero, Fernando, Llorca, Oscar
Format:	Artikel
Sprache:	eng
Schlagworte:	Candida glabrata - genetics Candida glabrata - metabolism Genome Integrity, Repair and Humans Protein Binding Shelterin Complex Telomere - genetics Telomere - metabolism Telomere-Binding Proteins - metabolism
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