7,8-Dihydroxyflavone and Neuropsychiatric Disorders: A Translational Perspective from the Mechanism to Drug Development

7,8-Dihydroxyflavone (7,8-DHF) is a kind of natural flavonoid with the potential to cross the blood-brain barrier. 7,8-DHF effectively mimics the effect of brain-derived neurotrophic factor (BDNF) in the brain to selectively activate tyrosine kinase receptor B (TrkB) and downstream signaling pathway...

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Veröffentlicht in:	Current neuropharmacology 2022-01, Vol.20 (8), p.1479-1497
Hauptverfasser:	Yang, Shaojie, Zhu, Guoqi
Format:	Artikel
Sprache:	eng
Schlagworte:	Drug Development Flavones - pharmacology Flavones - therapeutic use Humans Memory Disorders Neurology Receptor, trkB
Online-Zugang:	Volltext
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