Comparison of model predictions of typhoid conjugate vaccine public health impact and cost-effectiveness

•While model predictions varied, typhoid conjugate vaccines are likely cost-effective.•Differing structural assumptions can explain discrepancies in model predictions.•Static model estimates of vaccine impact are not necessarily conservative.•Increasing the contribution of chronic carriers decreased...

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Veröffentlicht in:	Vaccine 2023-01, Vol.41 (4), p.965-975
Hauptverfasser:	Burrows, Holly, Antillón, Marina, Gauld, Jillian S., Kim, Jong-Hoon, Mogasale, Vittal, Ryckman, Theresa, Andrews, Jason R., Lo, Nathan C., Pitzer, Virginia E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age groups Conjugates Cost analysis Cost-Benefit Analysis Economic analysis Economic evaluation Economic models Effectiveness Fever Humans Impact prediction Infections Mathematical modeling Mathematical models Model comparison Population Public Health Robustness (mathematics) Structural models Typhoid Typhoid conjugate vaccines Typhoid fever Typhoid Fever - epidemiology Typhoid Fever - prevention & control Typhoid-Paratyphoid Vaccines Vaccination Vaccine efficacy Vaccines Vaccines, Conjugate Waterborne diseases
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