Detection of Immune Microenvironment Changes and Immune-Related Regulators in Langerhans Cell Histiocytosis Bone Metastasis

The inflammation/immune response pathway is considered a key contributor to the development of Langerhans cell histiocytosis (LCH) bone metastasis. However, the dynamic changes in the immune microenvironment of LCH bone metastasis and critical regulators are still unclear. Expression profiling by ar...

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Veröffentlicht in:	BioMed research international 2023, Vol.2023 (1), p.1447435-1447435
Hauptverfasser:	Lin, Jinding, Tang, Haifeng, Xu, Zhitong, Zeng, Rongdong
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Autoimmune diseases Biomarkers Biomarkers - metabolism Bone cancer Bone lesions Bone Neoplasms - genetics CD8 antigen CD8-Positive T-Lymphocytes - metabolism Complications and side effects Correlation analysis CXCL16 protein Cytotoxicity Dendritic cells Development and progression Encyclopedias Gene expression Genes Genomes Health aspects Helper cells Histiocytosis Histiocytosis, Langerhans-Cell - diagnosis Histiocytosis, Langerhans-Cell - genetics Humans Immune response Immune system Immunologic Factors Immunotherapy Kinases Langerhans cell histiocytosis Lymphocytes Lymphocytes B Lymphocytes T MARCKS protein Metastases Metastasis Microenvironments Mutation Next-generation sequencing Protein Interaction Maps - genetics Proteins Risk factors Senescence Tumor Microenvironment - genetics
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