WT1 Pulsed Human CD141+ Dendritic Cell Vaccine Has High Potential in Solid Tumor-Targeted Immunotherapy

Dendritic cells (DC) are powerful cells that play critical roles in anti-tumor immunity, and their use in cancer immunotherapy unlocks hidden capabilities as an effective therapeutic. In order to maximize the full potential of DC, we developed a DC vaccine named CellgramDC-WT1 (CDW). CDW was pulsed...

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Veröffentlicht in:	International journal of molecular sciences 2023-01, Vol.24 (2), p.1501
Hauptverfasser:	Cho, Sung Yoon, Jeong, Seong Mun, Jeon, Young Joo, Yang, Sun Ja, Hwang, Ju Eun, Yoo, Byung Moo, Kim, Hyun Soo
Format:	Artikel
Sprache:	eng
Schlagworte:	Access control Antigen presentation Antigens Cancer Cancer immunotherapy Cancer therapies Cancer Vaccines CD8 antigen Cell differentiation Cells Cytokines Cytotoxicity Dendritic Cells Flow cytometry Humans Immune system Immunotherapy Interleukin 12 Kinases Lymphocytes Lymphocytes T Maturation Neoplasms - therapy Quality control Solid tumors T-Lymphocytes, Cytotoxic Vaccines WT1 Proteins Zoledronic acid Zoledronic Acid - pharmacology γ-Interferon
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