Potential Role of ROS in Butyrate- and Dietary Fiber-Mediated Growth Inhibition and Modulation of Cell Cycle-, Apoptosis- and Antioxidant-Relevant Proteins in LT97 Colon Adenoma and HT29 Colon Carcinoma Cells

The aim of the present study was to examine whether reactive oxygen species (ROS) contribute to chemopreventive effects of fermentation supernatants (FS) of different dietary fibers (Synergy1 , oat-, barley-, yeast β-glucan, Curdlan) and butyrate as a fermentation metabolite. LT97 and HT29 cells wer...

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Veröffentlicht in:	Cancers 2023-01, Vol.15 (2), p.440
Hauptverfasser:	Schlörmann, Wiebke, Horlebein, Christoph, Hübner, Sabine M, Wittwer, Elisa, Glei, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcysteine Adenoma Antioxidants Apoptosis Barley Cell culture Cell cycle Cell growth Colon cancer Colorectal cancer Cyclin D2 Cyclin-dependent kinase inhibitor p21 Cysteine Dietary fiber Experiments Fermentation GTP-binding protein Large intestine Mutation Oxidative stress Poly(ADP-ribose) polymerase Reactive oxygen species Tumors
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