Effect of ANKK1 Polymorphisms on Serum Valproic Acid Concentration in Chinese Han Adult Patients in the Early Postoperative Period

Introduction This study aimed to investigate the relationship between gene polymorphisms and clinical factors with the concentrations of valproic acid (VPA) in adult patients who underwent neurosurgery in China. Methods A total of 531 serum concentration samples at steady state were collected from 3...

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Veröffentlicht in:	Neurology and Therapy 2023-02, Vol.12 (1), p.197-209
Hauptverfasser:	Ma, Jiuhong, Fan, Xiuzhao, Cai, Xinfeng, Ji, Hongming, Li, Yuanping, Guo, Jinlin
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Divalproex Dosage and administration Internal Medicine Medicine Medicine & Public Health Nervous system Neurology Original Research Pharmacokinetics Single nucleotide polymorphisms Surgery Valproic acid
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