Opioid Rotation and Conversion Ratios Used by Palliative Care Professionals: An International Survey
The opioid rotation ratios (ORRs) and conversion ratios (CRs) used worldwide among palliative care (PC) professionals to perform opioid rotations (ORs) and route conversions may have a wide variation. We surveyed PC professionals on opioid ratios used through email to the Multinational Association o...
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Veröffentlicht in: | Journal of palliative medicine 2022-10, Vol.25 (10), p.1557-1562 |
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creator | Reddy, Akhila Sinclair, Christian Crawford, Gregory B McPherson, Mary Lynn Mercadante, Sebastiano Hui, David Haider, Ali Arthur, Joseph Tanco, Kimberson Dalal, Shalini Dev, Rony Amaram-Davila, Jaya Adile, Claudio Liu, Diane Schuler, Ulrich Jammi, Sheetal Shelal, Zeena Del Fabbro, Egidio Davis, Mellar Bruera, Eduardo |
description | The opioid rotation ratios (ORRs) and conversion ratios (CRs) used worldwide among palliative care (PC) professionals to perform opioid rotations (ORs) and route conversions may have a wide variation.
We surveyed PC professionals on opioid ratios used through email to the Multinational Association of Supportive Care in Cancer's PC study group and Twitter and Facebook posts between September and November 2020.
We received 370 responses from respondents from 53 countries: 276 (76%) were physicians, 46 (13%) advanced practice providers, 39 (11%) pharmacists, and 9 respondents did not report their profession. There were statistically significant variations in median CR from intravenous (IV) to oral morphine (2-3), IV to oral hydromorphone (2-4.5), ORR from IV hydromorphone to oral morphine (10-20), and ORR from transdermal fentanyl mcg/hour to oral morphine (2-3.5) across various groups.
This survey highlights the wide variation in ORRs and CRs among PC clinicians worldwide and the need for further research to standardize practice. |
doi_str_mv | 10.1089/jpm.2022.0266 |
format | Article |
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We surveyed PC professionals on opioid ratios used through email to the Multinational Association of Supportive Care in Cancer's PC study group and Twitter and Facebook posts between September and November 2020.
We received 370 responses from respondents from 53 countries: 276 (76%) were physicians, 46 (13%) advanced practice providers, 39 (11%) pharmacists, and 9 respondents did not report their profession. There were statistically significant variations in median CR from intravenous (IV) to oral morphine (2-3), IV to oral hydromorphone (2-4.5), ORR from IV hydromorphone to oral morphine (10-20), and ORR from transdermal fentanyl mcg/hour to oral morphine (2-3.5) across various groups.
This survey highlights the wide variation in ORRs and CRs among PC clinicians worldwide and the need for further research to standardize practice.</description><identifier>ISSN: 1096-6218</identifier><identifier>EISSN: 1557-7740</identifier><identifier>DOI: 10.1089/jpm.2022.0266</identifier><identifier>PMID: 35930252</identifier><language>eng</language><publisher>United States: Mary Ann Liebert, Inc., publishers</publisher><subject>Analgesics, Opioid - therapeutic use ; Brief Reports ; Fentanyl ; Humans ; Hydromorphone ; Morphine ; Neoplasms ; Palliative Care ; Surveys and Questionnaires</subject><ispartof>Journal of palliative medicine, 2022-10, Vol.25 (10), p.1557-1562</ispartof><rights>Copyright 2022, Mary Ann Liebert, Inc., publishers 2022 Mary Ann Liebert, Inc., publishers</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c387t-6e854926596c11666b07ed806c24e7ea98978c30e881a1414b0f5c7b4dcda4983</citedby><cites>FETCH-LOGICAL-c387t-6e854926596c11666b07ed806c24e7ea98978c30e881a1414b0f5c7b4dcda4983</cites><orcidid>0000-0001-8768-7519 ; 0000-0001-9859-6487 ; 0000-0002-7283-0519</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35930252$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Reddy, Akhila</creatorcontrib><creatorcontrib>Sinclair, Christian</creatorcontrib><creatorcontrib>Crawford, Gregory B</creatorcontrib><creatorcontrib>McPherson, Mary Lynn</creatorcontrib><creatorcontrib>Mercadante, Sebastiano</creatorcontrib><creatorcontrib>Hui, David</creatorcontrib><creatorcontrib>Haider, Ali</creatorcontrib><creatorcontrib>Arthur, Joseph</creatorcontrib><creatorcontrib>Tanco, Kimberson</creatorcontrib><creatorcontrib>Dalal, Shalini</creatorcontrib><creatorcontrib>Dev, Rony</creatorcontrib><creatorcontrib>Amaram-Davila, Jaya</creatorcontrib><creatorcontrib>Adile, Claudio</creatorcontrib><creatorcontrib>Liu, Diane</creatorcontrib><creatorcontrib>Schuler, Ulrich</creatorcontrib><creatorcontrib>Jammi, Sheetal</creatorcontrib><creatorcontrib>Shelal, Zeena</creatorcontrib><creatorcontrib>Del Fabbro, Egidio</creatorcontrib><creatorcontrib>Davis, Mellar</creatorcontrib><creatorcontrib>Bruera, Eduardo</creatorcontrib><title>Opioid Rotation and Conversion Ratios Used by Palliative Care Professionals: An International Survey</title><title>Journal of palliative medicine</title><addtitle>J Palliat Med</addtitle><description>The opioid rotation ratios (ORRs) and conversion ratios (CRs) used worldwide among palliative care (PC) professionals to perform opioid rotations (ORs) and route conversions may have a wide variation.
We surveyed PC professionals on opioid ratios used through email to the Multinational Association of Supportive Care in Cancer's PC study group and Twitter and Facebook posts between September and November 2020.
We received 370 responses from respondents from 53 countries: 276 (76%) were physicians, 46 (13%) advanced practice providers, 39 (11%) pharmacists, and 9 respondents did not report their profession. There were statistically significant variations in median CR from intravenous (IV) to oral morphine (2-3), IV to oral hydromorphone (2-4.5), ORR from IV hydromorphone to oral morphine (10-20), and ORR from transdermal fentanyl mcg/hour to oral morphine (2-3.5) across various groups.
This survey highlights the wide variation in ORRs and CRs among PC clinicians worldwide and the need for further research to standardize practice.</description><subject>Analgesics, Opioid - therapeutic use</subject><subject>Brief Reports</subject><subject>Fentanyl</subject><subject>Humans</subject><subject>Hydromorphone</subject><subject>Morphine</subject><subject>Neoplasms</subject><subject>Palliative Care</subject><subject>Surveys and Questionnaires</subject><issn>1096-6218</issn><issn>1557-7740</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkU1LAzEQhoMoVqtHr5Kjl61JdjcfHgQpfoGgVHsO2exUt2yTmmwL_fdmbRU9JZl55p3Ag9AZJSNKpLqcLxcjRhgbEcb5HjqiZSkyIQqyn-5E8YwzKgfoOMY5IWmAlIdokJcqJ6xkR6h-Xja-qfHEd6ZrvMPG1Xjs3RpC7J-TvhrxNEKNqw1-MW3bpNIa8NgEwC_BzyD2pGnjFb5x-NF1ENx3lmnx6yqsYXOCDmapD6e7c4imd7dv44fs6fn-cXzzlNlcii7jIMtCMV4qbinlnFdEQC0Jt6wAAUZJJaTNCUhJDS1oUZFZaUVV1LY2hZL5EF1vc5eragG1BdcF0-plaBYmbLQ3jf7fcc2HfvdrnWbTOpECLnYBwX-uIHZ60UQLbWsc-FXUjCslSCFkj2Zb1AYfY4DZ7xpKdG9GJzO6N6N7M4k___u3X_pHRf4FwfSLXg</recordid><startdate>20221001</startdate><enddate>20221001</enddate><creator>Reddy, Akhila</creator><creator>Sinclair, Christian</creator><creator>Crawford, Gregory B</creator><creator>McPherson, Mary Lynn</creator><creator>Mercadante, Sebastiano</creator><creator>Hui, David</creator><creator>Haider, Ali</creator><creator>Arthur, Joseph</creator><creator>Tanco, Kimberson</creator><creator>Dalal, Shalini</creator><creator>Dev, Rony</creator><creator>Amaram-Davila, Jaya</creator><creator>Adile, Claudio</creator><creator>Liu, Diane</creator><creator>Schuler, Ulrich</creator><creator>Jammi, Sheetal</creator><creator>Shelal, Zeena</creator><creator>Del Fabbro, Egidio</creator><creator>Davis, Mellar</creator><creator>Bruera, Eduardo</creator><general>Mary Ann Liebert, Inc., publishers</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-8768-7519</orcidid><orcidid>https://orcid.org/0000-0001-9859-6487</orcidid><orcidid>https://orcid.org/0000-0002-7283-0519</orcidid></search><sort><creationdate>20221001</creationdate><title>Opioid Rotation and Conversion Ratios Used by Palliative Care Professionals: An International Survey</title><author>Reddy, Akhila ; 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We surveyed PC professionals on opioid ratios used through email to the Multinational Association of Supportive Care in Cancer's PC study group and Twitter and Facebook posts between September and November 2020.
We received 370 responses from respondents from 53 countries: 276 (76%) were physicians, 46 (13%) advanced practice providers, 39 (11%) pharmacists, and 9 respondents did not report their profession. There were statistically significant variations in median CR from intravenous (IV) to oral morphine (2-3), IV to oral hydromorphone (2-4.5), ORR from IV hydromorphone to oral morphine (10-20), and ORR from transdermal fentanyl mcg/hour to oral morphine (2-3.5) across various groups.
This survey highlights the wide variation in ORRs and CRs among PC clinicians worldwide and the need for further research to standardize practice.</abstract><cop>United States</cop><pub>Mary Ann Liebert, Inc., publishers</pub><pmid>35930252</pmid><doi>10.1089/jpm.2022.0266</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0001-8768-7519</orcidid><orcidid>https://orcid.org/0000-0001-9859-6487</orcidid><orcidid>https://orcid.org/0000-0002-7283-0519</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Analgesics, Opioid - therapeutic use Brief Reports Fentanyl Humans Hydromorphone Morphine Neoplasms Palliative Care Surveys and Questionnaires |
title | Opioid Rotation and Conversion Ratios Used by Palliative Care Professionals: An International Survey |
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