Opioid Rotation and Conversion Ratios Used by Palliative Care Professionals: An International Survey

The opioid rotation ratios (ORRs) and conversion ratios (CRs) used worldwide among palliative care (PC) professionals to perform opioid rotations (ORs) and route conversions may have a wide variation. We surveyed PC professionals on opioid ratios used through email to the Multinational Association o...

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Veröffentlicht in:Journal of palliative medicine 2022-10, Vol.25 (10), p.1557-1562
Hauptverfasser: Reddy, Akhila, Sinclair, Christian, Crawford, Gregory B, McPherson, Mary Lynn, Mercadante, Sebastiano, Hui, David, Haider, Ali, Arthur, Joseph, Tanco, Kimberson, Dalal, Shalini, Dev, Rony, Amaram-Davila, Jaya, Adile, Claudio, Liu, Diane, Schuler, Ulrich, Jammi, Sheetal, Shelal, Zeena, Del Fabbro, Egidio, Davis, Mellar, Bruera, Eduardo
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container_end_page 1562
container_issue 10
container_start_page 1557
container_title Journal of palliative medicine
container_volume 25
creator Reddy, Akhila
Sinclair, Christian
Crawford, Gregory B
McPherson, Mary Lynn
Mercadante, Sebastiano
Hui, David
Haider, Ali
Arthur, Joseph
Tanco, Kimberson
Dalal, Shalini
Dev, Rony
Amaram-Davila, Jaya
Adile, Claudio
Liu, Diane
Schuler, Ulrich
Jammi, Sheetal
Shelal, Zeena
Del Fabbro, Egidio
Davis, Mellar
Bruera, Eduardo
description The opioid rotation ratios (ORRs) and conversion ratios (CRs) used worldwide among palliative care (PC) professionals to perform opioid rotations (ORs) and route conversions may have a wide variation. We surveyed PC professionals on opioid ratios used through email to the Multinational Association of Supportive Care in Cancer's PC study group and Twitter and Facebook posts between September and November 2020. We received 370 responses from respondents from 53 countries: 276 (76%) were physicians, 46 (13%) advanced practice providers, 39 (11%) pharmacists, and 9 respondents did not report their profession. There were statistically significant variations in median CR from intravenous (IV) to oral morphine (2-3), IV to oral hydromorphone (2-4.5), ORR from IV hydromorphone to oral morphine (10-20), and ORR from transdermal fentanyl mcg/hour to oral morphine (2-3.5) across various groups. This survey highlights the wide variation in ORRs and CRs among PC clinicians worldwide and the need for further research to standardize practice.
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subjects Analgesics, Opioid - therapeutic use
Brief Reports
Fentanyl
Humans
Hydromorphone
Morphine
Neoplasms
Palliative Care
Surveys and Questionnaires
title Opioid Rotation and Conversion Ratios Used by Palliative Care Professionals: An International Survey
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