Development of an in-vitro high-throughput screening system to identify modulators of genitalia development

Sexually dimorphic outgrowth and differentiation of the embryonic genital tubercles (GTs) give rise to the penis in males and the clitoris in females. Defects in androgen production or in response to androgen signaling can lead to various congenital penile anomalies in both mice and humans. Due to l...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	PNAS nexus 2023-01, Vol.2 (1), p.pgac300-pgac300
Hauptverfasser:	Yin, Yan, Haller, Meade, Li, Tian, Ma, Liang
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgens Cell differentiation Genetic disorders Genetic engineering Genomics High-throughput screening (Biochemical assaying) Methods Penis Physiological aspects Physiological research Reproductive organs Research Report Stem cells Vascular endothelial growth factor
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!