Blood miR-144-3p: a novel diagnostic and therapeutic tool for depression

Major depressive disorder (MDD) is the leading cause of disability worldwide. There is an urgent need for objective biomarkers to diagnose this highly heterogeneous syndrome, assign treatment, and evaluate treatment response and prognosis. MicroRNAs (miRNAs) are short non-coding RNAs, which are dete...

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Veröffentlicht in:	Molecular psychiatry 2022-11, Vol.27 (11), p.4536-4549
Hauptverfasser:	van der Zee, Yentl Y., Eijssen, Lars M. T., Mews, Philipp, Ramakrishnan, Aarthi, Alvarez, Kelvin, Lardner, Casey K., Cates, Hannah M., Walker, Deena M., Torres-Berrío, Angélica, Browne, Caleb J., Cunningham, Ashley, Cathomas, Flurin, Kronman, Hope, Parise, Eric M., de Nijs, Laurence, Shen, Li, Murrough, James W., Rutten, Bart P. F., Nestler, Eric J., Issler, Orna
Format:	Artikel
Sprache:	eng
Schlagworte:	38/61 38/77 42/44 45/61 631/154/53/2421 631/1647 631/337 631/378 64 64/60 692/699/476/1414 Animals Antidepressive Agents - pharmacology Antidepressive Agents - therapeutic use Behavioral Sciences Biological Psychology Biomarkers Blood Body fluids Depressive Disorder, Major - diagnosis Depressive Disorder, Major - drug therapy Depressive Disorder, Major - genetics Diagnosis Epigenesis, Genetic Epigenetics Erythrocytes Imipramine Ketamine Ketamine - pharmacology Ketamine - therapeutic use Medicine Medicine & Public Health Mental depression Mice MicroRNAs MicroRNAs - metabolism miRNA Neurosciences Pharmacotherapy Phenotypes Psychiatry Sequence analysis Social interactions
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